Pairwise Alignments

Query, 245 a.a., 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase from Vibrio cholerae E7946 ATCC 55056

Subject, 245 a.a., Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) from Sphingobium sp. HT1-2

 Score =  142 bits (358), Expect = 6e-39
 Identities = 87/246 (35%), Positives = 132/246 (53%), Gaps = 10/246 (4%)

Query: 1   MIIPALDLIEGQVVRLYQGDYGQVTEYKVDPAEQFNLYHQAGAGWLHLVDLTGAKNTAAR 60
           ++ PA+DL  GQVVRL +GD  + T Y  DPA Q  ++  AGA  +H+VDL G+    A 
Sbjct: 4   IVFPAIDLKGGQVVRLAEGDMDRATVYGDDPAAQALIFAAAGAQHIHVVDLDGSFAGHAV 63

Query: 61  QLNLIARLLASTPANIQIGGGVRSEQDVVDLLEAGAQRVVVGSTAVKQPQLVKSWIEKYG 120
               + R++ + P ++Q+GGG+R+ + V    + G  R+V+G+ A+K P  VK+    + 
Sbjct: 64  NAEAVERIVEAFPGHVQLGGGIRNRESVERWFDLGVSRIVIGTAALKDPAFVKAAARDFP 123

Query: 121 AEKIVLALDINIDEQGTRKVAISGWQEDSGVTIEALIDDYLTVGLQHVLCTDISRDGTLA 180
              IV+A+D          VA  GW E S + +  L   +   G+  +L TD+ RDG L 
Sbjct: 124 G-GIVVAVDAR-----DGFVATDGWAEKSDMPVIDLARRFEDAGVASLLFTDVGRDGLLK 177

Query: 181 GSNVELYRDLCRQYPQVQFQSSGGIGSLADIEALK---GTGVAGVIVGRALLDGKFTAQE 237
           G N++   DL R    +   +SGG+  +ADI  L      G+ GVI GRA+ DG+   + 
Sbjct: 178 GVNIDATVDLARA-TDMPVIASGGVAGIADIRVLSLHADDGIEGVITGRAIYDGRLDLKT 236

Query: 238 AFACWQ 243
           A A  Q
Sbjct: 237 ALAVAQ 242