Pairwise Alignments

Query, 431 a.a., histidinol dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 440 a.a., Histidinol dehydrogenase (EC 1.1.1.23) from Variovorax sp. SCN45

 Score =  297 bits (760), Expect = 5e-85
 Identities = 167/413 (40%), Positives = 242/413 (58%), Gaps = 13/413 (3%)

Query: 25  EGANITAAVAQVIAKVRSEGDAALFELTEKFDRVKPASL---RVSREEMDAAAARLSETM 81
           + A I   VA ++A VR  GD A+ E T +FD++   +L    +++ E+ AA   L    
Sbjct: 31  DDAAIEKVVADILADVRKRGDEAVLEYTNRFDKLDAKTLPELELTQAELKAAFESLPAAQ 90

Query: 82  KQALEQAYNNISKFHKAQK---AQPIKVETMPGVVCEQVTRPINKVGLYIPGGSAPLPST 138
           + ALE A   +  +H+AQK    +        G +  Q   P+++VG+Y+PGG A  PS+
Sbjct: 91  RDALEAAARRVRSYHEAQKKASGESWSYRDADGTLLGQKVTPLDRVGIYVPGGKAAYPSS 150

Query: 139 VLMLGVPAQIAGCRKVVLCSPPPIADE---ILYVAKLCNIDEVYNLGGGQAIAAMAYGTE 195
           VLM  +PA +AG  ++++  P P  ++   +L  A +  +   + +GG QA+AA+AYGT 
Sbjct: 151 VLMNAIPAHVAGVGEIIMVVPTPKGEKNQLVLAAAYVAGVTRGFTIGGAQAVAALAYGTA 210

Query: 196 TVTKVDKIFGPGNAYVTEAKRQVSNDFRGAAIDMPAGPSEVLVIADETADANFIAADLLS 255
           TV  VDKI GPGNAYV  AKR+V   F    IDM AGPSE+LV+AD +   +++A DL S
Sbjct: 211 TVPAVDKITGPGNAYVAAAKRRV---FGTVGIDMIAGPSEILVLADGSTPPDWVAMDLFS 267

Query: 256 QAEHGPDSQVVLVTPSPVLADQVTDAVQKQLKVLSRASIAEKAL-ASSLIIIAESLTQAV 314
           QAEH   +Q +L+ P     D+V   + + L  + RA I   +L     +I  +S+ +A 
Sbjct: 268 QAEHDELAQSILLCPDAAYIDRVQAEIDRLLPAMPRAEIIAASLNGRGALIHTKSMEEAC 327

Query: 315 SISNYYGPEHLIVQTRNPRELVPLLDNAGSIFLGDWSPESVGDYASGTNHVLPTYGYTRT 374
            ISN   PEHL V +  P    PLL +AG+IFLG ++ ES+GDY +G NHVLPT G  R 
Sbjct: 328 EISNRIAPEHLEVSSSQPDRWEPLLRHAGAIFLGAFTSESLGDYCAGPNHVLPTSGTARF 387

Query: 375 YSSLGLADFSKRMTVQELTADGLQLLAPTVVTMAEAEGLDAHKRAVTIRVEKL 427
            S LG+ DF KR ++ E++  G Q+L P  VT+AE EGL AH  A  +R+ K+
Sbjct: 388 SSPLGVYDFQKRSSLIEVSEAGAQVLGPIAVTLAEGEGLQAHAEAARMRLRKI 440