Pairwise Alignments

Query, 683 a.a., methionine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 677 a.a., methionine--tRNA ligase from Escherichia coli ECRC62

 Score = 1038 bits (2684), Expect = 0.0
 Identities = 500/684 (73%), Positives = 577/684 (84%), Gaps = 10/684 (1%)

Query: 1   MANDPRKLLVTCALPYANGSIHLGHMLEHIQADIWVRYQRLRGNTVNFICADDAHGTPIM 60
           M    +K+LVTCALPYANGSIHLGHMLEHIQAD+WVRYQR+RG+ VNFICADDAHGTPIM
Sbjct: 1   MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIM 60

Query: 61  LKAQQMGMTPEAMIEMVSEEHQRDFAGFDISFDNYHSTHSDENRELASHIYLQLKKNGFI 120
           LKAQQ+G+TPE MI  +S+EHQ DFAGF+IS+DNYHSTHS+ENR+L+  IY +LK+NGFI
Sbjct: 61  LKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFI 120

Query: 121 SSRTISQLFDPEKEMFLPDRFVKGTCPKCKSEDQYGDNCDACGETYSPTELINPKSAVSG 180
            +RTISQL+DPEK MFLPDRFVKGTCPKCKS DQYGDNC+ CG TYSPTELI PKS VSG
Sbjct: 121 KNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSG 180

Query: 181 ATPVMKDSEHFFFDLPQFESMLKEWTRSGSLQSETANKMQEWFEGGLQQWDISRDAPYFG 240
           ATPVM+DSEHFFFDLP F  ML+ WTRSG+LQ + ANKMQEWFE GLQQWDISRDAPYFG
Sbjct: 181 ATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFG 240

Query: 241 FEIPGEKDKFFYVWLDAPIGYMGSFKNLCDKRGD-LDFNEYWNKDSKTELYHFIGKDIVY 299
           FEIP    K+FYVWLDAPIGYMGSFKNLCDKRGD + F+EYW KDS  ELYHFIGKDIVY
Sbjct: 241 FEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVY 300

Query: 300 FHSLFWPAMLDGSGFRKPTNVFVHGYVTVNGAKMSKSKGTFVKASTYLNHLDPECLRYYY 359
           FHSLFWPAML+GS FRKPTN+FVHGYVTVNGAKMSKS+GTF+KAST+LNH D + LRYYY
Sbjct: 301 FHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYY 360

Query: 360 AAKLNNRIDDLDLNLEDFTQRVNADVVNKIVNLASRNAGFITKRFDGKLSAHFAEPELYA 419
            AKL++RIDD+DLNLEDF QRVNAD+VNK+VNLASRNAGFI KRFDG L++  A+P+LY 
Sbjct: 361 TAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYK 420

Query: 420 EFAGAADRIAELFEAREFGRAIREITALADKANQYVDEKAPWVVAKQEGQDQALQDICTV 479
            F  AA+ I E +E+REFG+A+REI ALAD AN+YVDE+APWVVAKQEG+D  LQ IC++
Sbjct: 421 TFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSM 480

Query: 480 GINLFRVLMTYLKPVMPALAERTEAFLNQELTWEGVATPLTDHAVTPFKALFNRIDPKQV 539
           GINLFRVLMTYLKPV+P L ER EAFLN ELTW+G+  PL  H V PFKAL+NRID KQV
Sbjct: 481 GINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQV 540

Query: 540 EAMIEASKAEAAAEKAAADAAKPKSAETELSKDPLAAEIEFDDFAKVDLRIAKILSCEAV 599
           EA++EASK E  A  AAA    P      L+ DP+   I FDDFAKVDLR+A I + E V
Sbjct: 541 EALVEASKEEVKA--AAAPVTGP------LADDPIQETITFDDFAKVDLRVALIENAEFV 592

Query: 600 EKSDKLLKFELDIGGETRQVFSGIKSAY-QPEDLIGKYTVVVANLKPRKMKFGMSEGMIL 658
           E SDKLL+  LD+GGE R VFSGI+SAY  P+ LIG++T++VANL PRKM+FG+SEGM++
Sbjct: 593 EGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVM 652

Query: 659 AAGPGGSDLWLLEPHQGAQAGMRV 682
           AAGPGG D++LL P  GA+ G +V
Sbjct: 653 AAGPGGKDIFLLSPDAGAKPGHQV 676