Pairwise Alignments

Query, 768 a.a., zinc/cadmium/mercury/lead-transporting ATPase from Vibrio cholerae E7946 ATCC 55056

Subject, 732 a.a., zinc, cobalt and lead efflux system from Escherichia coli BL21

 Score =  750 bits (1937), Expect = 0.0
 Identities = 415/722 (57%), Positives = 521/722 (72%), Gaps = 20/722 (2%)

Query: 45  DSCCTSDGGGGATLEEDPERRHEPRSSHYQQSWYIAGMDCPSCAQKIEKAVKQLGDVTQV 104
           D CC        TL E+         S Y  SW ++GMDC +CA+K+E AV+QL  V QV
Sbjct: 28  DCCCDGACSSSPTLSENVS------GSRY--SWKVSGMDCAACARKVENAVRQLAGVNQV 79

Query: 105 QVMFATQKLVVGFNQPSTAPLIEQAVRDSGFSLNPAASSAATPSQSKPPLWQSENARIIG 164
           QV+FAT+KLVV  +    A  +E  V+ +G+SL     +A  P  S+      EN  +I 
Sbjct: 80  QVLFATEKLVVDADNDIRAQ-VESTVQKAGYSLRDE-QAADEPQASR----LKENLPLIT 133

Query: 165 IAALMAI--GALVNSSEMSRWIYTLTCLLGLFPILQQAWRLAKSGSPFSIETLMSVAAIG 222
           +  +MAI  G    +    +  +  T L+GL+PI +QA RL KSGS F+IETLMSVAAIG
Sbjct: 134 LIVMMAISWGLEQFNHPFGQLAFIATTLVGLYPIARQALRLIKSGSYFAIETLMSVAAIG 193

Query: 223 ALYLGETLEAAMVLLLFLIGERLEAYAASRARTGVQALMALVPETAIRIEHGERVTVPAA 282
           AL++G T EAAMVLLLFLIGERLE +AASRAR GV ALMAL PETA R+ +GER  V   
Sbjct: 194 ALFIGATAEAAMVLLLFLIGERLEGWAASRARQGVSALMALKPETATRLRNGEREEVAIN 253

Query: 283 QLQPGDVIEVAPGGRLPADGRLLAA-ASLDNSALTGESLPVELTAGERVSAGCVIVDKVV 341
            L+PGDVIEVA GGRLPADG+LL+  AS D SALTGES+PVE   G++V AG   VD++V
Sbjct: 254 SLRPGDVIEVAAGGRLPADGKLLSPFASFDESALTGESIPVERATGDKVPAGATSVDRLV 313

Query: 342 QIEITSKQGENAIDRILHMIEEAESRKAPLERFLDKFSRWYTPLMMLVALAVIVVPPLAF 401
            +E+ S+ G +AIDRIL +IEEAE R+AP+ERF+D+FSR YTP +M VAL V +VPPL F
Sbjct: 314 TLEVLSEPGASAIDRILKLIEEAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLF 373

Query: 402 GADWQTWIYRGLALLLIACPCALVISTPAAITSGLAAAARRGALIKGGAALEQLGKIETI 461
            A WQ WIY+GL LLLI CPCALVISTPAAITSGLAAAARRGALIKGGAALEQLG++  +
Sbjct: 374 AASWQEWIYKGLTLLLIGCPCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQV 433

Query: 462 AFDKTGTLTEGKPQVTDLIPLQGWDSATLLARAAAIEMGSHHPLATSLVAKAQAEQLTIP 521
           AFDKTGTLT GKP+VT + P  G   + LL  AAA+E G+ HPLA ++V +AQ   L IP
Sbjct: 434 AFDKTGTLTVGKPRVTAIHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAALAIP 493

Query: 522 QAQERTALVGRGISGQIDGVQYRLLAPNRVETKLPDVVKQHVEMLEAESKTVVVMLASDA 581
            A+ + ALVG GI  Q++G +  + A  +      D     +  LE+  +TVV+++ +D 
Sbjct: 494 AAESQRALVGSGIEAQVNGERVLICAAGKHPA---DAFAGLINELESAGQTVVLVVRNDD 550

Query: 582 VVGVIAWQDTLRSDARQAVAALHQLGINALMLTGDNERSAAAMSQQLNMDFRAGLLPQDK 641
           V+G+IA QDTLR+DA  A++ L+ LG+  ++LTGDN R+AAA++ +L ++F+AGLLP+DK
Sbjct: 551 VLGIIALQDTLRADAATAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDK 610

Query: 642 VGYIQQLAQHQRVAMVGDGINDAPAMKEASIGIAMGGGTDVALETADAALTHNRLIELPG 701
           V  + +L QH  +AMVGDGINDAPAMK A+IGIAMG GTDVALETADAALTHN L  L  
Sbjct: 611 VKAVTELNQHAPLAMVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQ 670

Query: 702 MIELSRATLAIIRQNVVLALGLKAVFLVTSLLGITGLWMAVLADSGATALVTLNALRLLK 761
           MIEL+RAT A IRQN+ +ALGLK +FLVT+LLG+TGLW+AVLAD+GAT LVT NALRLL+
Sbjct: 671 MIELTRATHANIRQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLR 730

Query: 762 FR 763
            R
Sbjct: 731 RR 732