Pairwise Alignments

Query, 858 a.a., leucine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 876 a.a., Leucyl-tRNA synthetase (EC 6.1.1.4) from Variovorax sp. SCN45

 Score =  853 bits (2205), Expect = 0.0
 Identities = 427/877 (48%), Positives = 571/877 (65%), Gaps = 23/877 (2%)

Query: 1   MQEQYNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGRLHMGHVRNYTIGD 60
           M   Y P D+E   Q  W     + V+ED +++K+Y  SM PYPSG+LHMGHVRNYTI D
Sbjct: 1   MNPSYKPSDVESAAQAQWSAADAYRVTEDASRKKYYACSMLPYPSGKLHMGHVRNYTIND 60

Query: 61  VVSRFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYD 120
           +++R+ R+ G NVL P+GWDAFGLPAENAA+KN   PA WTYENI YMK QL+ +G   D
Sbjct: 61  MLTRYLRMSGYNVLMPMGWDAFGLPAENAALKNGVPPAKWTYENIAYMKGQLQAMGLAID 120

Query: 121 WNREFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQVEDGCCWRCD 180
           W+RE ATC P YY+W Q  F K+  KG+ Y+KT  VNW P DQTVLANEQV DG  WR  
Sbjct: 121 WSREIATCDPSYYKWNQWLFLKMLEKGIAYRKTQVVNWDPVDQTVLANEQVIDGKGWRTG 180

Query: 181 TPVEQKEIPQWFIKITAYAQELLDDLDN-LDGWPEMVKTMQRNWIGRSEGVELKFA--VK 237
             VE++EIP +++KI+ YA+ELL+   + L GWPE VK MQ NWIG+SEG+   F   +K
Sbjct: 181 ATVERREIPGYYLKISDYAEELLEHTQHKLPGWPERVKLMQENWIGKSEGLRFAFTHDIK 240

Query: 238 G------ENTDLEVYTTRPDTLMGVTYVGIAAGHPLATKAAANNPALAAFIDECKNTKVA 291
                  ++  + V+TTR DT+MGVT+  +A  HPLA  AA  +P +AAFI+ECKN    
Sbjct: 241 DASGKPIQDGRMYVFTTRADTIMGVTFCAVAPEHPLAAHAATLDPKVAAFIEECKNGGTT 300

Query: 292 EAEIATMEKKGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATK 351
           EAE+AT EKKG+ TGLT  HP+   +VP+++ N+VL+ YG GAVM VPAHD+RDF FA K
Sbjct: 301 EAELATQEKKGVPTGLTVTHPITDEQVPVWVGNYVLIGYGDGAVMGVPAHDERDFAFANK 360

Query: 352 YGLDIIPVIKPADGSELDVSE----AAYTEKGVLFASGEFDGLDFQAAFNAIAAKLEAEG 407
           YG++II V+   D    D  +        ++GV   S  F G+ ++ A  A+A  L  +G
Sbjct: 361 YGIEIIQVVLVDDEPHFDYHKWQDWYGDKQRGVTINSDNFSGMTYKEAVAAVAHALGQKG 420

Query: 408 KGKKTVNFRLRDWGVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILPEDVVMDGVTSPI 467
            G+    +RLRDWGVSRQRYWG PIP++  E+    PVP   LPV+LP D V DG  +P+
Sbjct: 421 LGELQTTWRLRDWGVSRQRYWGTPIPIIHCEEHGAVPVPEKDLPVVLPTDCVPDGSGNPL 480

Query: 468 KADKEW---AKTTFNGEPALRETDTFDTFMESSWYYARYCSPQADDILDPEKANYWLPVD 524
              + +         G+PA RETDT DTF++SSWY+ RYC P+ D+ +    A+YW+P+D
Sbjct: 481 HKHEGFHAGVVCPVCGKPARRETDTMDTFVDSSWYFMRYCDPKNDEAMVAGGADYWMPMD 540

Query: 525 QYIGGIEHACMHLLYSRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEW 584
           QYIGGIEHA +HLLY+RF+ K++RD G +K+DEPF KLL QGMVL   FY  N+KGGK++
Sbjct: 541 QYIGGIEHAILHLLYARFWTKVMRDLGLLKADEPFSKLLTQGMVLNHIFYKRNEKGGKDY 600

Query: 585 VSPTEVKVERDGKGRIVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLF 644
             PTEV    D +GRIV    A G +VE+ G+ KM KS+ NG+DPQ++++KYGADT RL+
Sbjct: 601 FPPTEVTTVLDAQGRIVGGTTADGTKVEYGGVGKMGKSERNGVDPQDLIEKYGADTARLY 660

Query: 645 MMFASPADMTLEWQESGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDV 704
            MF +P + TLEW ++ VEG+ RFLRRVW       ++    A    A     +ALRR+V
Sbjct: 661 TMFTAPPEATLEWNDAAVEGSYRFLRRVWNFGAAQADVAPVAAA-GQAFGKGAQALRREV 719

Query: 705 HKTIAKVTDDVARRQTFNTAIAAIMELMNKLTK-APMTEAQDRAILDEALKAITLMLYPI 763
           H  + +V  D  R Q +NT ++  M+L+N L    P   A D A + E    +   LYP 
Sbjct: 720 HTVLRQVDYDYQRMQ-YNTVVSGAMKLLNALEGFKPDGSAGDAAAVREGFGILLRCLYPA 778

Query: 764 TPHICFEMWVALGQ----SNIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADAT 819
           TPHI  ++W  LG       +  A WPT D  ALV+DE  ++LQVNGKLRGKL+V A A+
Sbjct: 779 TPHIAQQLWNELGYDKDLGGLLDAPWPTVDVGALVQDEIELMLQVNGKLRGKLSVPAGAS 838

Query: 820 QQQVEALGMQDENVQKFIDGLTVRKVIYVPGKLLNIV 856
           + ++E L +  ++   F +G   ++VI VPG+L+N+V
Sbjct: 839 KDEIEKLALACDDFVAFAEGAQPKRVIVVPGRLVNVV 875