Pairwise Alignments

Query, 858 a.a., leucine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 860 a.a., Leucyl-tRNA synthetase (EC 6.1.1.4) from Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

 Score = 1341 bits (3471), Expect = 0.0
 Identities = 648/858 (75%), Positives = 724/858 (84%), Gaps = 2/858 (0%)

Query: 1   MQEQYNPQDIEHKVQQHWDNNKTFVVSEDPNKEKFYCLSMFPYPSGRLHMGHVRNYTIGD 60
           MQEQY P++IE KVQ HWD  +TF V+ED +KEK+YCLSM PYPSGRLHMGHVRNYTIGD
Sbjct: 1   MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGD 60

Query: 61  VVSRFQRLQGKNVLQPIGWDAFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYD 120
           VV+R+QR+ GKNVLQPIGWDAFGLPAE AAVKNNTAPAPWTY+NI YMKNQLK LGFGYD
Sbjct: 61  VVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYD 120

Query: 121 WNREFATCRPEYYRWEQEFFTKLFAKGLVYKKTSSVNWCPNDQTVLANEQVEDGCCWRCD 180
           W+RE ATC PEYYRWEQ+FFT+L+ KGLVYKKTS+VNWCPNDQTVLANEQV DGCCWRCD
Sbjct: 121 WSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCD 180

Query: 181 TPVEQKEIPQWFIKITAYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELKFAVKGEN 240
           T VE+KEIPQWFIKITAYA ELL DLD LD WP+ VKTMQRNWIGRSEGVE+ F VKG +
Sbjct: 181 TKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYD 240

Query: 241 TDLEVYTTRPDTLMGVTYVGIAAGHPLATKAAANNPALAAFIDECKNTKVAEAEIATMEK 300
             L VYTTRPDT MG TY+ +AAGHPLA KAAANN  LAAFIDEC+NTKVAEAE+ATMEK
Sbjct: 241 NTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEK 300

Query: 301 KGMATGLTAIHPLNGREVPIYIANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPVI 360
           KG+ TG  AIHPL G E+P++ ANFVLM+YGTGAVMAVP HDQRD+EFA+KYGL I PVI
Sbjct: 301 KGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVI 360

Query: 361 KPADGSELDVSEAAYTEKGVLFASGEFDGLDFQAAFNAIAAKLEAEGKGKKTVNFRLRDW 420
             ADGSE D+SE A TEKGVLF SGEFDGL F+AAFNAIA KL  +G G++ VN+RLRDW
Sbjct: 361 LAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDW 420

Query: 421 GVSRQRYWGAPIPMVTTEDGQVHPVPADQLPVILPEDVVMDGVTSPIKADKEWAKTTFNG 480
           GVSRQRYWGAPIPMVT EDG V P P DQLPVILPEDVVMDG+TSPIKAD EWAKTT NG
Sbjct: 421 GVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG 480

Query: 481 EPALRETDTFDTFMESSWYYARYCSPQ-ADDILDPEKANYWLPVDQYIGGIEHACMHLLY 539
            PALRETDTFDTFMESSWYYARY  PQ  + +LD + ANYWLPVD YIGGIEHA MHLLY
Sbjct: 481 MPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLY 540

Query: 540 SRFFHKLLRDAGYVKSDEPFKKLLCQGMVLADAFYYTNDKGGKEWVSPTEVKVERDGKGR 599
            RFFHKL+RDAG V SDEP K+LLCQGMVLADAFYY  + G + WVSP +  VERD KGR
Sbjct: 541 FRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGR 600

Query: 600 IVSAVDATGRQVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMTLEWQE 659
           IV A DA G ++ ++GM KMSKSKNNGIDPQ MV++YGADTVRLFMMFASPADMTLEWQE
Sbjct: 601 IVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQE 660

Query: 660 SGVEGANRFLRRVWKLVREHTELGQAPALDASALNADQKALRRDVHKTIAKVTDDVARRQ 719
           SGVEGANRF++RVWKLV EHT  G   AL+  AL+ DQKALRRDVHKTIAKVTDD+ RRQ
Sbjct: 661 SGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQ 720

Query: 720 TFNTAIAAIMELMNKLTKAPMTEAQDRAILDEALKAITLMLYPITPHICFEMWVAL-GQS 778
           TFNTAIAAIMELMNKL KAP    QDRA+L EAL+A+  ML P TPH+CF +W  L G+ 
Sbjct: 721 TFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEG 780

Query: 779 NIDTASWPTYDEAALVEDEKLIVLQVNGKLRGKLTVAADATQQQVEALGMQDENVQKFID 838
           +ID A WP  DE A+VE+  L+V+QVNGK+RGK+TV  DAT++QV     Q+  V K++D
Sbjct: 781 DIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVPVDATEEQVRERAGQEHLVAKYLD 840

Query: 839 GLTVRKVIYVPGKLLNIV 856
           G+TVRKVIYVPGKLLN+V
Sbjct: 841 GVTVRKVIYVPGKLLNLV 858