Pairwise Alignments

Query, 638 a.a., penicillin-binding protein 2 from Vibrio cholerae E7946 ATCC 55056

Subject, 662 a.a., Peptidoglycan D,D-transpeptidase MrdA (EC 3.4.16.4) from Variovorax sp. SCN45

 Score =  463 bits (1191), Expect = e-134
 Identities = 246/626 (39%), Positives = 375/626 (59%), Gaps = 17/626 (2%)

Query: 8   IRDHQAETHLFRNRAIVSFVGILICMGLLVTNLYNIQINQYQDYKTRSNDNRIKVVPIAP 67
           IR+  AE   FR R +V    +L   GL+   L  +Q+ ++++   R+  NR  +VPI P
Sbjct: 4   IRNAAAELSRFRRRVVVVGCVVLFGFGLIGARLAFLQVVRHEELADRAESNRTAIVPIVP 63

Query: 68  NRGLIFDRNGVLLAENRPVFNLEVIPEKVPNMEETIARLQQLIEISPEKLAAFEKERKQT 127
           NRG I DRNGV+LA N   + LE+ P KV ++   +  L  ++EI+P     F++ R+ +
Sbjct: 64  NRGQILDRNGVVLASNYAAYTLEITPSKVGDLNAALDELDAIVEITPNDRRRFKRLREDS 123

Query: 128 RRFNSVPLLTQLTDDEVAKFSVNQHKFPGVSVTANLKRYYPYGEVLTHVIGYVSRINDKD 187
           R F+S+P+ T+L+D+EVA+F+  +++FPG+ + A L R YP+GEV +HVIGY+ RIN ++
Sbjct: 124 RSFDSIPIRTRLSDEEVARFAAQRYRFPGIEIKARLFRSYPHGEVASHVIGYIGRINQRE 183

Query: 188 LERLD--KEGKKANYQATRDIGKLGIERYYEDLLHGTAGYQEVEVNSRGRVIRTLKYVPP 245
              ++   E ++ANY+ T  IGKLGIE+ YE  LHG  G +++E ++ GR +R L   P 
Sbjct: 184 KTAMEDWDEEEQANYRGTDYIGKLGIEQSYEKTLHGQTGVEQMETSAGGRAVRRLARHPA 243

Query: 246 IPGKDIVLNLDIELQLYAYKLLEGRRGSIVALDPKDNGVLAMASSPSYDPNAFVHGISGK 305
            PG  ++L+LDI+LQ     +   RRG++VA+DPK   +LA  S P++DPN FV GI  +
Sbjct: 244 TPGNTVMLSLDIKLQKLVEDMFGERRGALVAIDPKTGEILAFVSKPTFDPNLFVEGIDHE 303

Query: 306 AYSDLLNDKRRPLVNRTTLGIYPPGSTVKPFIAVSALQDGIITPNTTRNDPGYWRIPNTD 365
           +++ L+    +PL+NR   G YPPGST KPF+A++AL+ G    +   NDPG +      
Sbjct: 304 SWAALIESIDKPLLNRALRGTYPPGSTYKPFMALAALETGARAADKIENDPGSYSFGG-- 361

Query: 366 TRPFRDWLRWGHGRVDIIKSLEESVDTFFYQIAYDMGIDKLSSWMMRFGFGDLTGIDIYE 425
            R F    R G G VD+ ++++ S +T+FY +A +MG+D +  +M   GFG  TGID+  
Sbjct: 362 -RTFLSH-RGGLGGVDMHRAIQFSSNTYFYSLANEMGVDLIHEFMAPLGFGQFTGIDLLG 419

Query: 426 ESKANMPTREWKMARHKVP----WYQGDTIPVGIGQGYWTATPMQIAKATSVLVNHGKVI 481
           ES+  +P++ WK A ++ P    W+ G+TI +GIGQGY + T +Q+A A + L N G   
Sbjct: 420 ESRGVLPSKAWKRAAYRRPDMKTWHAGETISLGIGQGYNSFTMLQLASANATLANGGMHY 479

Query: 482 APHLLRATIDN-GEQFSTQKETEYTTYPPIDGVPKKYWDMAIHGMYLVNHGAKGTARRAF 540
            PHL+RA  D   E+   Q + +        G  +K+ D+  + M  V  G  GT  R F
Sbjct: 480 RPHLVRAIKDTVTEEIVAQVQPQARDL----GYAQKHVDVVRNAMVAVTKG--GTGTRVF 533

Query: 541 QNMPYESAGKSGTAQVFGLAEGQKYNASELAEHLHDHALFTGFAPVKDPKVIVTFVLENG 600
               Y SAGK+GTAQ   L    + +   L E   DHAL+  FAP + P + V  ++EN 
Sbjct: 534 AGAAYTSAGKTGTAQAVSLGPKARASGKALEERQRDHALYMAFAPAEAPTIAVAAIVENA 593

Query: 601 GGGSSNGAPVVRQIFDHVILGKKEEE 626
           G G+++ AP+VR++FD+ I G+   E
Sbjct: 594 GFGAAHAAPIVRRVFDYWIAGQYPNE 619