Pairwise Alignments

Query, 957 a.a., hemolysin from Vibrio cholerae E7946 ATCC 55056

Subject, 691 a.a., hemolysin from Vibrio cholerae E7946 ATCC 55056

 Score =  704 bits (1818), Expect = 0.0
 Identities = 357/668 (53%), Positives = 465/668 (69%), Gaps = 73/668 (10%)

Query: 217 YDGDSSALNMKLKWSWQGSAFQPNSNQVMVTPIVAQLNDDNGDGKIDEKDVADLIVVTFE 276
           +   SS +  KLKWSW  S F P SNQVM  PIV QLNDDNGDGKIDEKDVAD+IVVTFE
Sbjct: 25  FASSSSDIQTKLKWSWSTSVFHPESNQVMAAPIVVQLNDDNGDGKIDEKDVADIIVVTFE 84

Query: 277 GNKYANGGLVRALSGVDGSELWSYANGGVIADARYSPAVGDLDGDGIVEIVTTNNRDQFI 336
           GNKYANGG +RALSGVDGSELWSY+NGGVIADARY+PA  DLDGDG++EIV+T+    +I
Sbjct: 85  GNKYANGGYIRALSGVDGSELWSYSNGGVIADARYAPAAADLDGDGLIEIVSTSALTPYI 144

Query: 337 TILDNQGNIKKQIPTTESGWRIVGDITLADLDHDGSVEILAADGVYNYHSGLVFNHPWAP 396
            ILD+QGNIKKQ+  + SGWR VGDI LAD++ DG++EILAADGVY+Y SGL+F+H WAP
Sbjct: 145 NILDHQGNIKKQLLKSASGWRSVGDIALADINGDGNIEILAADGVYSYESGLLFSHDWAP 204

Query: 397 SSINVDVDGDQQQEVFSGGTLFQNNGAINWQYQANDAVWFSSLVNLDNDAEPEIVASVPA 456
           SSI  D +GD Q+EVF+ GTL+QNNGA  WQYQAND VWFSS+ NLD D +PE+V SVPA
Sbjct: 205 SSIAFDSNGDGQREVFANGTLYQNNGAYLWQYQANDTVWFSSVANLDGDDKPELVVSVPA 264

Query: 457 TFATGDNARFAVLEHDGTIKWEINNTANPGGGVQAVSNFLGK--AQAVETSEFSKVYGYQ 514
           + +T +N+  AVLEHDG++KW +NN +NPGG VQAVS+FLGK  + A      S VYGY 
Sbjct: 265 SLSTPENSEIAVLEHDGSVKWRVNNLSNPGGSVQAVSSFLGKPSSSATTVDAQSAVYGYT 324

Query: 515 PNNNPASIALAVDGKISVRSGFAIDAIGASASTLVGGTGGNLNAAVNVKDIKAIDLTWGK 574
              +   + LA + ++++RSG  +DAIGA++  ++GG+GG+L+  ++   ++AID+T+GK
Sbjct: 325 DWAHQQRV-LAENHQLAIRSGAVVDAIGANSQNMIGGSGGSLST-IDTSKVRAIDVTYGK 382

Query: 575 --YYWGGYHLLALDFRMSNGSVISMG---------------------------------- 598
             Y W  Y +L + F + NG+ +++G                                  
Sbjct: 383 NKYTWK-YGVLEMSFTLDNGAKVTVGSKDSAFTYLGLEWKTKTVPYLGVEWRTKTVSYWF 441

Query: 599 ----SKNYAY-------------------SKQTERFTVPAGSRIKGIKAWTAGWLL---- 631
               +K  AY                      T R+ +P GS++ G+  W+    L    
Sbjct: 442 FGWHTKQVAYLAPVWKEKTIPYAVPVTLSKSTTVRYDIPQGSQLLGMNVWSKEKHLFKHK 501

Query: 632 ---DGVQFELATQNGTNDLDVKGIVYAGYAAVDMYNSKGERVWSVANDDTGSGKIGVSAY 688
              + VQF +     T D    GIVYAGY AVDMY+++G +VWSVANDD  SGKIGVSAY
Sbjct: 502 QQVNAVQFLVGKV--TADQSHMGIVYAGYYAVDMYDAQGNKVWSVANDDLNSGKIGVSAY 559

Query: 689 DFDNDGIDEVLVQDHARVRVLDGKTGKERASLAHSTATLWEYPIVVDLEGDNNAELIVAA 748
           DF  DGIDEVLVQD  R+R+LDG+TG+    +A+S+ TLWEYP+V DLEG+NNA LI+ A
Sbjct: 560 DFTGDGIDEVLVQDRLRMRILDGQTGRVMGIIANSSGTLWEYPVVADLEGNNNASLIMVA 619

Query: 749 NDFDRQYSINHGVYVYQSADSSKPWKNATRIWNQHAFHLTNINQDGTLPTFVEPSWLSHN 808
           ND+DR+  +NHGV+VY+SA+ SKPW+NATRIWNQ+AF+ ++IN +GT+PT  +PSWL+HN
Sbjct: 620 NDYDRESQVNHGVFVYESANPSKPWRNATRIWNQYAFNFSDINANGTIPTNAQPSWLTHN 679

Query: 809 TYRSSTLR 816
           ++RS+T+R
Sbjct: 680 SFRSATIR 687



 Score = 68.2 bits (165), Expect = 2e-15
 Identities = 63/231 (27%), Positives = 111/231 (48%), Gaps = 35/231 (15%)

Query: 726 TLWEYPIVVDLEGDNNAELIVAANDFDRQYSINHGVYVYQSADSSKPWKNATRIWNQHAF 785
           T+W +  V +L+GD+  EL+V+          N  + V +  D S  W+           
Sbjct: 241 TVW-FSSVANLDGDDKPELVVSV-PASLSTPENSEIAVLEH-DGSVKWR----------- 286

Query: 786 HLTNINQDGTLPTFVEPSWLSHNTYRSSTLRAAVGGESPIFGYSNTQQSQRVVTADNLMY 845
            + N++  G     V  S+L     + S+    V  +S ++GY++    QRV+  ++ + 
Sbjct: 287 -VNNLSNPGGSVQAVS-SFLG----KPSSSATTVDAQSAVYGYTDWAHQQRVLAENHQLA 340

Query: 846 LRSGFAIDAIGTTVNNLVGGPVQGTNGGVLRAPIALDQLQSVEVTSG--LYNWGGYHIVA 903
           +RSG  +DAIG    N++GG     +GG L + I   ++++++VT G   Y W  Y ++ 
Sbjct: 341 IRSGAVVDAIGANSQNMIGG-----SGGSL-STIDTSKVRAIDVTYGKNKYTW-KYGVLE 393

Query: 904 IKFTMKDGSSVLLGSTHYA---SNKKVETYTVPQ---GKRIKQINVWTGGW 948
           + FT+ +G+ V +GS   A      + +T TVP      R K ++ W  GW
Sbjct: 394 MSFTLDNGAKVTVGSKDSAFTYLGLEWKTKTVPYLGVEWRTKTVSYWFFGW 444