Pairwise Alignments

Query, 1036 a.a., AcrB/AcrD/AcrF family protein from Vibrio cholerae E7946 ATCC 55056

Subject, 1037 a.a., The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family from Enterobacter asburiae PDN3

 Score =  513 bits (1320), Expect = e-149
 Identities = 321/1033 (31%), Positives = 538/1033 (52%), Gaps = 34/1033 (3%)

Query: 3    LSDVSVKRPVAALVLSMLLCVFGVVSFTKLAVREMPDIESPVVSVSTRYQGASATIIESQ 62
            +++  + RP+ A VL++LLC+ GV++ T L V + PD+  P V V+  Y GASA  +E+ 
Sbjct: 1    MANFFIDRPIFAWVLAILLCLTGVLAITSLPVEQYPDLAPPNVRVTANYPGASAQTLENT 60

Query: 63   ITSVLEDQLAGISGIDEITSVSR-NGMSRITVTFELGYDLNTGVSDIRDAVARAQRSLPE 121
            +T V+E  + G+  +  ++S S   G + +T++F+ G D +  V  +++ +  A R LP+
Sbjct: 61   VTQVIEQNMTGLDNLMYMSSQSSATGQATVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQ 120

Query: 122  EADDPQVF--KNNGSGQASVYINLSSSEMDRTQLTDYIERVLLDRFSLISGVSSVDVSGG 179
               +  V   K   +   ++    +   MD+  + DY+   + D  S I+GV  +D  G 
Sbjct: 121  AVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQDPISRINGVGDIDAYGS 180

Query: 180  LYKVMYVRIKPELMAGRGVATSDISDALNKENLESPGGQVRNDSTV------MSVRTARG 233
             Y  M + + P  +    +  +D+++A+  +N +   GQ+    +V       ++ +   
Sbjct: 181  QYS-MRIWLDPNKLNSVQMTATDVTNAIKAQNAQIAVGQLGGTPSVDKQALNATINSQSL 239

Query: 234  YQSAEDFEYLVVKRASDGTPIYLKDVADVFIGAENENSTFKSDGIVNVSMGIVPQSDANP 293
             Q+ + F  + ++   DG+ + L DVA V +GAE  +   + +G     +GI   S AN 
Sbjct: 240  LQTPDQFRNITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGNQASGLGIKLASGANE 299

Query: 294  LEVAKRVHEEVDKVQQFLPKGTRLAIDYDSTVFIERSISEVYSTLFITGGLVILVLYIFI 353
            +  AK V + +D++ Q+ P G    + Y++T F++ SI +V  TL     LV LV+Y+F+
Sbjct: 300  MATAKLVLDRLDELSQYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFL 359

Query: 354  GQLRATLIPAVTVPVSLISAFMAAYYFGFSINLITLMALILSIGLVVDDAIVVVENIFHH 413
               RATLIP + VPV L+  F   Y FG+SIN +T+ A++L+IGL+VDDAIVVVEN+   
Sbjct: 360  QNFRATLIPTIAVPVVLLGTFAVLYAFGYSINTLTMFAMVLAIGLLVDDAIVVVENVERI 419

Query: 414  I-ERGEKPLLAAYKGTREVGFAVIATTLVLVMVFLPISFMDGMVGLLFTEFSVLLAMAVI 472
            + E G  P  A  K   ++  A++   +VL  VF+P++F  G  G ++ +FS+ +  A++
Sbjct: 420  MSEEGLSPRQATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGTTGAIYRQFSITIVSAMV 479

Query: 473  FSSLIALTLTPVLGSKLLKANVKP---------GRFNQLIDRLFARLESGYRQVVSRAIR 523
             S L+AL LTP L + +LK   K          G FN++ +R  AR ES    V+ R++R
Sbjct: 480  LSVLVALILTPALCATILKPLHKGEQHGQKGFFGWFNRMFNRNAARYESAVGGVLHRSLR 539

Query: 524  WRWAAPVVIAACIGGSYGLMQLVPAQLTPSEDRGVIFSFVRGADATSYNRMAANMDLVEQ 583
            W     ++    +GG   L   +P    P EDRG+  + V+     +  +    +  VEQ
Sbjct: 540  WM----MIYVVLLGGMVWLFMHLPTSFLPMEDRGMFTTSVQLPSGATQQQTLKVVQKVEQ 595

Query: 584  RLMPLLGQGFLKSFSIQSPAFGGNAGDQTGFVIMILEDWNDR---TVTAQEALSQVRKAL 640
                      +  FS      GGN G     + + L+DW++R   T T+   + +  KA 
Sbjct: 596  YFFTKEKDNVVSVFSTVGSGPGGN-GQNVARMFVRLKDWDERDTKTGTSFAIIERATKAF 654

Query: 641  AGIPDVRVFPFMPGFRGGSNEPVQFVL-----GGSDYSELKTWAEKLEEEAEKSPFMTGA 695
            A I + RVF   P    G      F +      G+ ++ L    +KL   A   P +T  
Sbjct: 655  AHIKEARVFASSPPAISGLGSSAGFDMELQDHAGAGHTALMAARDKLLALAGNDPGLTRV 714

Query: 696  DIDYSEKTPELVVTIDKQRAAELGISVKSISDTLEVMLGGKKVTTFVERGEEYDVYLRGD 755
              +  + +P+L V ID+++A  LG+S+  I+DTL+   G   V  F++RG    VY++  
Sbjct: 715  RHNGLDDSPQLQVDIDQRKAQALGVSINDINDTLQTAWGSSYVNDFMDRGRVKKVYVQSA 774

Query: 756  ENSFNNAADLSQIYMRTATGELVTLDTVTRIDEVASAIRLAHYNKQKSVTITANLEAGYT 815
                    D+++ ++R   G +V           + + RL  YN   +V I      G +
Sbjct: 775  APFRMLPDDINRWFVRNNAGGMVPFSAFATSHWESGSPRLERYNGYSAVEIVGEAAPGVS 834

Query: 816  LGQALDFLDQKAQEILPNDISVSYSGESKDFKENQSSVAIVFALALLVAYLVLAAQFESF 875
             G A+D +++  Q+ LP    + ++  S   + + +    ++AL+LLV +L LAA +ES+
Sbjct: 835  TGTAMDTMEKLVQQ-LPAGFGLEWTAMSYQERLSGAQAPALYALSLLVVFLCLAALYESW 893

Query: 876  INPLVVMLTVPMGVFGGFLGLFVMGQGMNIYSQIGMIMLIGMVTKNGILIVEFANQLRDR 935
              P  VML VP+GV G  L  ++ G   ++Y Q+G++ +IG+  KN ILIVEFAN++  +
Sbjct: 894  SVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNAK 953

Query: 936  GVEFEKAIIDASARRLRPILMTAFTTLAGSIPLIVSTGAGYESRIAVGTVIFFGMGFATL 995
            G E   A + A  +RLRPILMT+   + G +P+  STGAG  S+ AVGT +  GM  AT+
Sbjct: 954  GHELMAATLHACRQRLRPILMTSLAFVFGVLPMATSTGAGSSSQHAVGTGVMGGMISATV 1013

Query: 996  VTLLVIPAMYRLI 1008
            + +  +P  + L+
Sbjct: 1014 LAIYFVPLFFVLV 1026