Pairwise Alignments

Query, 571 a.a., proline--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 581 a.a., Prolyl-tRNA synthetase (EC 6.1.1.15), bacterial type from Hydrogenophaga sp. GW460-11-11-14-LB1

 Score =  625 bits (1612), Expect = 0.0
 Identities = 319/580 (55%), Positives = 410/580 (70%), Gaps = 11/580 (1%)

Query: 1   MRTSNYLLSTLKETPNDAEVVSHKLMLRAGMIRKLASGLYTWLPTGLRVLRKVENIVRQE 60
           M+ S +L+STLKE P DAEVVSH+LM RAGMI+KL +G+Y+++P GLRV+ KVE IVR+E
Sbjct: 1   MKASQFLISTLKEAPADAEVVSHQLMTRAGMIKKLGAGIYSYMPMGLRVIHKVEAIVREE 60

Query: 61  IDNAGAIETLMPVVQPFELWEETGRSEKMGPELLRFTDRHERPFVLSPTAEEVITALVRN 120
           ++ AG++E  MPV+QP E W+ETGR +KMG ELLR  DRH+R FV+ PT+EEV+T + R 
Sbjct: 61  MNRAGSVELTMPVIQPAEYWQETGRFDKMGAELLRIKDRHDRDFVVQPTSEEVVTDIARQ 120

Query: 121 EVSSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFCMMDAYSFDIDKAGLEKSYEAMHVA 180
           +  SYKQLP NLYQIQTKFRDERRPRFG+MR REF M DAYSFD D++  + SY+ M  A
Sbjct: 121 DFRSYKQLPKNLYQIQTKFRDERRPRFGLMRGREFIMKDAYSFDRDESTAKLSYQVMAGA 180

Query: 181 YCKAFDRMGLDYRPVLADTGAIGGNGSHEFHVLAESGEDLIAFSTESDYAANIEKAEAVA 240
           Y + FDR GL YR V AD+GAIGG+ S EF V+A +GED I +   SDYAAN+EKAEA+A
Sbjct: 181 YRRIFDRFGLRYRAVAADSGAIGGDLSEEFQVIAATGEDAIVYCPASDYAANMEKAEALA 240

Query: 241 PAIERPAPTQAMTLVDTPNAKTIAELVEQHGLPIEKTVKTLFVKASDEID-------API 293
           PA  RPA    M    TP   T A++    G+P+  TVK+L V A+DE++       + +
Sbjct: 241 PAGPRPAAANPMAKTPTPGKATCADVATLLGVPLATTVKSL-VLATDELNEAGEIVKSQV 299

Query: 294 VALIIRGDHELNEIKAEKLAEVASPLEMASEEEIRALIGAGPGSLGPVGLKLP--FIVDR 351
             L++RGDH++NE+K  K+  + +    A+  EI    G  PG LGP+GLK P   +VDR
Sbjct: 300 WLLLLRGDHDMNEVKVAKVPGLNAGFRFATGAEIDTHFGCKPGYLGPIGLKKPVNLVVDR 359

Query: 352 TVAVMNDFGAGANIDGKHYFGINWGRDV-ELGKVEDLRNVVEGDPSPCGKGTLMLKRGIE 410
            VAV+ D+  GAN    H  G+NWGRD+ E   V DLRNVVEGD SP GKG L ++RGIE
Sbjct: 360 EVAVLADWICGANEPDFHMTGVNWGRDLPEPTLVADLRNVVEGDASPDGKGVLAIERGIE 419

Query: 411 VGHIFQLGTNYSEKMNCGVLDSNGKNVILEMGCYGIGVSRVVAAAIEQNHDDYGIIWPDA 470
           VGH+F LGT YS+ MN   L  +GK    EMGCYGIG++R+ AAAIEQNHD+ GIIWPDA
Sbjct: 420 VGHVFYLGTKYSKAMNATFLGEDGKPAHFEMGCYGIGITRLPAAAIEQNHDERGIIWPDA 479

Query: 471 IAPFQVAIVPMNMHKSERVQQAAEKLYAELTAAGIEVLFDDRKERPGVMFSDMELIGVPH 530
           +APF V + P+ M +S  V+ AAE+LY EL AAG++V+ DDR ERPG MF+D ELIGVPH
Sbjct: 480 LAPFTVVVCPIGMDRSPEVKAAAEQLYGELLAAGVDVILDDRGERPGAMFADWELIGVPH 539

Query: 531 TIIIGDRSMDEGHFEYKNRRQGEKEAVAMESIIDFIQAKL 570
            + IGDR +  G  EY++RR      VA+  ++  ++ KL
Sbjct: 540 RVTIGDRGLKAGQVEYQHRRDAAATQVAVGDVVSLLKGKL 579