Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 1298 a.a., phosphoribosylformylglycinamidine synthase from Pseudomonas simiae WCS417

 Score = 1735 bits (4493), Expect = 0.0
 Identities = 855/1296 (65%), Positives = 1027/1296 (79%), Gaps = 5/1296 (0%)

Query: 1    MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTY 60
            M ILRG+PALS FR +KLL    ++   VTG+YAEF HFAD+   L   E + L +LL Y
Sbjct: 1    MLILRGAPALSAFRHSKLLEQLSQKVPAVTGLYAEFAHFADVTGVLTADEQQVLARLLKY 60

Query: 61   GPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLHGIKRLERGTAYYVEAETALT 120
            GP++   EP G L LV PR GTISPWSSKA+DIA NCGL  I+RLERG A+YV  + +  
Sbjct: 61   GPSVPVQEPNGRLFLVLPRFGTISPWSSKASDIARNCGLEKIQRLERGIAFYVAGQFSDA 120

Query: 121  AAQIATLEALLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGRRALEEANVSLGL 180
             A++  + + LHDRM +++ ++L  A  LFS AEP P++ +DVL GGR ALE+AN  LGL
Sbjct: 121  EAEL--IASSLHDRMTQIIVSQLEQAGGLFSHAEPKPLTAIDVLGGGRAALEKANTELGL 178

Query: 181  ALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKM 240
            ALAEDEIDYLV +F  L RNP+DIELMMFAQANSEHCRHKIFNA W IDG  Q+KSLF M
Sbjct: 179  ALAEDEIDYLVNAFNGLKRNPHDIELMMFAQANSEHCRHKIFNASWDIDGESQEKSLFGM 238

Query: 241  IKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYHHEDAHILMKVETHNHPT 300
            IKNT+    + VLSAYKDNA+V+ GS  GRFFPDPE+RQY    E  HILMKVETHNHPT
Sbjct: 239  IKNTYVMHSEGVLSAYKDNASVIVGSVAGRFFPDPETRQYGAVQEPVHILMKVETHNHPT 298

Query: 301  AISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPSRIV 360
            AI+P+PGA+TGSGGEIRDEGATG G KPKAGL GFT SNL+IPGFEQPWE  +GKP RIV
Sbjct: 299  AIAPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFEQPWEVPYGKPDRIV 358

Query: 361  NALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNI 420
             ALDIM+EGPLGGAAFNNEFGRP L GYFRT+E+ +T+  G+EVRGYHKPIM+AGGMGNI
Sbjct: 359  TALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPRGDEVRGYHKPIMLAGGMGNI 418

Query: 421  RAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERR 480
            R EH++K EI VG+KLIVLGGPAM IGLGGGAASSMA+G S+ DLDFASVQRENPEMERR
Sbjct: 419  REEHVKKGEILVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPEMERR 478

Query: 481  CQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPL 540
            CQEVIDRCWQLGDKNPI+FIHDVGAGG+SNA PELVNDGDRGG+F+LRN+PNDEPGM+P 
Sbjct: 479  CQEVIDRCWQLGDKNPISFIHDVGAGGLSNAFPELVNDGDRGGRFELRNIPNDEPGMAPH 538

Query: 541  EIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDM 600
            EIW NESQERYVLAV AED   F AIC+RER P+AVVGEAT E  LT+ DSHF N+P+DM
Sbjct: 539  EIWSNESQERYVLAVGAEDFARFQAICERERCPFAVVGEATAEPQLTVTDSHFGNSPVDM 598

Query: 601  PMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRVLRLPAVAEKTFLITIGDRSV 660
            P+++LLGK P+MHR A          + S +EL ++++RVL  PAVA K+FLITIGDR++
Sbjct: 599  PLEVLLGKAPRMHRSAVREAELGDDFDPSQLELADSIERVLHHPAVASKSFLITIGDRTI 658

Query: 661  TGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAI 720
            TGLVARDQMVGPWQVPVA+ AVTA SFD Y GEAM+MGERTP+ALLD  AS R+A+GE +
Sbjct: 659  TGLVARDQMVGPWQVPVADVAVTATSFDVYTGEAMAMGERTPLALLDAPASGRMAIGETL 718

Query: 721  TNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKDSMS 780
            TNIAA+ IG+L  IKLSANWMS AGHPGEDA LY+ VKAVG ELCP LGITIPVGKDSMS
Sbjct: 719  TNIAASRIGKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKDSMS 778

Query: 781  MKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRL 840
            M T+W E+G  K VTSPLSLI+T FA V DIR+T+TPQLR D G T LILIDLG GQNR+
Sbjct: 779  MATRWNEDGVDKTVTSPLSLIVTGFAPVTDIRQTLTPQLRMDKGTTDLILIDLGRGQNRM 838

Query: 841  GATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMA 900
            GA+ LAQ + +LG +  DVD+A  LK FF  +Q L  +  L+AYHD+ DGGLL ++ EMA
Sbjct: 839  GASILAQTHGKLGKQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLLTSVVEMA 898

Query: 901  FAGHCGIKANIETLGDDAL---AALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHVI 957
            FAGHCG+   ++++ +DA      LFNEELGAV+QV+ D    VLA  +A GL+ C  VI
Sbjct: 899  FAGHCGLNIVLDSVAEDASEINGILFNEELGAVIQVRQDATPDVLAQFSAAGLDDCVAVI 958

Query: 958  GEVEASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDP 1017
            G+   +  + I+   + +    R  L+  WAE ++++Q LRDN+ CA+QEF    +  +P
Sbjct: 959  GQPINNGEINISFNGDTVFAGQRRLLQRQWAETSYQIQRLRDNADCAEQEFDVILEEDNP 1018

Query: 1018 GLNAKLTYDVQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDI 1077
            GL+ KL++DV  D+AAPYI KG+RP++A+LREQGVN  VEMAAAFDRAGF+A+DVHMSDI
Sbjct: 1019 GLSTKLSFDVNQDIAAPYIKKGIRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDVHMSDI 1078

Query: 1078 LTGQTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVC 1137
            L G+  L+A++GLVACGGFSYGDVLGAGEGWAKS LFN++AR+ F+ FF+R D+F+LGVC
Sbjct: 1079 LAGRVDLNAFKGLVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERNDSFTLGVC 1138

Query: 1138 NGCQMLSNLRDLIPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVS 1197
            NGCQM+SNL +LIPG+E WP FVRN S++FEAR ++V+VQ+S S+F   MAGSRMPIA++
Sbjct: 1139 NGCQMMSNLSELIPGSEFWPHFVRNRSEQFEARVAMVQVQESNSIFLQGMAGSRMPIAIA 1198

Query: 1198 HGEGRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVT 1257
            HGEG  E    + L   + SGTVA+RFVDN G+ T+ YP+NPNGSP  ITGLT++DGRVT
Sbjct: 1199 HGEGHAEFASEEALLEADLSGTVALRFVDNHGKVTETYPANPNGSPRGITGLTSRDGRVT 1258

Query: 1258 IMMPHPERVFRTVANSWHPDNWGENGAWMRMFQNAR 1293
            IMMPHPERVFR V NSW P+ W E+GAWMRMF+NAR
Sbjct: 1259 IMMPHPERVFRAVQNSWRPEEWNEDGAWMRMFRNAR 1294