Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 1336 a.a., Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) from Hydrogenophaga sp. GW460-11-11-14-LB1

 Score = 1393 bits (3605), Expect = 0.0
 Identities = 742/1348 (55%), Positives = 911/1348 (67%), Gaps = 67/1348 (4%)

Query: 1    MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTY 60
            +R   G  A+S+F+V ++L         +TG+ A F+H A    E +   L+++ +LLTY
Sbjct: 5    LRFFEGGNAVSDFKVQQILPRLAGISDKITGLSARFVHLASFDGEPDAATLQRVGELLTY 64

Query: 61   G----PTIQEHEPQGL-LLLVTPRPGTISPWSSKATDIAHNCGLHGIKRLERGTAYYVEA 115
            G    P   + E  G   LLV PR GT+SPW+SKATDIAHNCGL  + R+ER   Y V  
Sbjct: 65   GEPGTPAHAQLEAAGAPALLVMPRLGTVSPWASKATDIAHNCGL-ALHRVERLVEYRVGL 123

Query: 116  ET-------ALTAAQIATLEALLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGR 168
            ++       +L+  Q+  +  LLHDRM E V  + + AQ LF+   PAPM QVDVL GGR
Sbjct: 124  KSGLLGKKASLSEEQLRAVADLLHDRMTENVSLDRSQAQALFTELHPAPMEQVDVLGGGR 183

Query: 169  RALEEANVSLGLALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTI 228
             ALE AN   GLALA+DEIDYLV +F  L RNP D+ELMMFAQANSEHCRHKIFNA +TI
Sbjct: 184  AALERANADWGLALADDEIDYLVNAFNGLKRNPTDVELMMFAQANSEHCRHKIFNAQFTI 243

Query: 229  DGVKQDKSLFKMIKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFP---DPESRQYTYHHE 285
            DG  QDKSLF MI++T +Q P + + AY DNA++M GS V RF        S  Y     
Sbjct: 244  DGAAQDKSLFGMIRHTHQQAPQHTVVAYSDNASIMEGSVVERFVARAGGDTSPAYAAETA 303

Query: 286  DAHILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGF 345
              H+LMKVETHNHPTAISP+PGASTG+GGEIRDEGATG G KPKAGL GFT   L     
Sbjct: 304  THHVLMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGSKPKAGLTGFTVGKLWGGLS 363

Query: 346  EQPWESDFGKPSRIVNALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVR 405
            +QP     GKP  I + L IM EGPLGGAAFNNEFGRPNLLGYFR YE  V        R
Sbjct: 364  DQPG----GKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLLGYFREYELAVYGVQ----R 415

Query: 406  GYHKPIMIAGGMGNIRAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDL 465
            GYHKPIMIAGG+G I A   +K E P G+ LI LGGP M IG+GG AASSMA+G +A  L
Sbjct: 416  GYHKPIMIAGGVGVIDAIQTKKIEFPAGSLLIQLGGPGMKIGMGGSAASSMATGTNAASL 475

Query: 466  DFASVQRENPEMERRCQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKF 525
            DF SVQR NPE+ERR QEVI+ CWQ G+ NPI  IHDVGAGG+SNA PEL ND  RG +F
Sbjct: 476  DFDSVQRGNPEIERRAQEVINHCWQQGENNPILAIHDVGAGGLSNAFPELTNDAGRGARF 535

Query: 526  QLRNVPNDEPGMSPLEIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERH 585
             LR VP +E G++P EIWCNESQERYVLA+A E +PLF A C+RER P+AV+G ATEER 
Sbjct: 536  DLRAVPLEESGLAPKEIWCNESQERYVLAIAPESLPLFQAFCERERCPFAVIGVATEERQ 595

Query: 586  LTLEDSHFANTPIDMPMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRVLRLPA 645
            L L D     +P+DMPM++LLGKPPKMHR+  ++   +  LE +G+ L +AV  VL  P 
Sbjct: 596  LVLADEG-QQSPVDMPMNVLLGKPPKMHRDVKSVARQATPLELTGVNLQQAVIDVLSHPT 654

Query: 646  VAEKTFLITIGDRSVTGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVAL 705
            VA K FLITIGDR+V GL  RDQMVGPWQVPVA+CAVT A +  + GEAMSMGERTP+A 
Sbjct: 655  VASKRFLITIGDRTVGGLSHRDQMVGPWQVPVADCAVTLADYKGFAGEAMSMGERTPLAA 714

Query: 706  LDFGASARLAVGEAITNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELC 765
            LD  AS R+AV EAITN+ A  I EL R+KLSANWM+  G PGEDA LY+ VKAVG ELC
Sbjct: 715  LDAAASGRMAVAEAITNLLAAPI-ELPRVKLSANWMAACGEPGEDAALYDTVKAVGLELC 773

Query: 766  PALGITIPVGKDSMSMKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGE 825
            PALGI+IPVGKDS+SM+T+W+E GE K+VTSP+SLI++AFA + D+R T+TPQL   L +
Sbjct: 774  PALGISIPVGKDSLSMRTQWREGGETKKVTSPVSLIVSAFATLADVRGTLTPQLNNALED 833

Query: 826  TSLILIDLGNGQNRLGATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYH 885
            T+L+LIDLG G++R+G + LAQV  Q G +  D+D+A  L    +AV  L    +++AYH
Sbjct: 834  TTLVLIDLGKGRHRMGGSVLAQVLGQGGGEVPDLDDAKDLVSLVNAVNALRAQGQILAYH 893

Query: 886  DKGDGGLLVTLAEMAFAGHCGIKANIETL---GDD------------------------- 917
            D+ DGGLL   AEMAFAGH G+  N++ L   GD                          
Sbjct: 894  DRSDGGLLAAAAEMAFAGHVGVALNVDLLVTEGDGISDSRAEMGDAKNWAGQVSARREEL 953

Query: 918  ALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHVIGEVEASD--------RLLIT 969
             L ALF+EELG ++QV+ ++ NAV+ TL  HGL   +H +G+   +         +L + 
Sbjct: 954  TLKALFSEELGVLLQVRTEDRNAVMQTLREHGLSKHSHFVGKTRPASSAMDAGKGQLQVW 1013

Query: 970  CGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDPGLNAKLTYDVQA 1029
               + +   S  +L+ +W  ++ K+   RDN A AD E AA     DPGL+ KLT+D   
Sbjct: 1014 RDTKAVFSASLFDLQQVWDSVSWKINQQRDNPAGADAEHAAAGQPDDPGLHTKLTFDAAD 1073

Query: 1030 DVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTGQTVLDAYQG 1089
            +VA P++    RPK+AILREQGVNSHVEMA AF +AGF+A DVHM+D+ TG+  L  ++G
Sbjct: 1074 NVATPFL-NLARPKVAILREQGVNSHVEMAYAFTQAGFEAFDVHMTDLQTGRAKLADFKG 1132

Query: 1090 LVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGCQMLSNLRDL 1149
            +VACGGFSYGD LGAG GWA+SI FN    EQF+ FF R DTF LGVCNGCQM + L D+
Sbjct: 1133 VVACGGFSYGDTLGAGIGWARSITFNPGLSEQFQAFFGRSDTFGLGVCNGCQMFAELADI 1192

Query: 1150 IPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVSHGEGRVEVRDAQ 1209
            IPGAE WPRF  N+S+RFEAR SLVEV  SPSLF   MAGSR+PIAV+HGEG    R   
Sbjct: 1193 IPGAEAWPRFTTNQSERFEARLSLVEVLDSPSLFLQGMAGSRLPIAVAHGEGYANFRHRG 1252

Query: 1210 HLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMMPHPERVFRT 1269
                       A+RF D+ G  T+AYP NPNGSP  +T +TT DGR T MMPHPERVFR 
Sbjct: 1253 DAG----KAIAAMRFTDHSGAATEAYPFNPNGSPGGLTAVTTADGRFTAMMPHPERVFRN 1308

Query: 1270 VANSWHPDNWGENGAWMRMFQNARKYFG 1297
            +  SW   +     AWMR+++NAR++ G
Sbjct: 1309 IQMSWTDQDPAAFSAWMRLWRNARRWVG 1336