Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 1295 a.a., Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) from Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

 Score = 1966 bits (5093), Expect = 0.0
 Identities = 960/1297 (74%), Positives = 1095/1297 (84%), Gaps = 3/1297 (0%)

Query: 1    MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTY 60
            M ILRGSPALS FR+NKLL   +   L V  IYAE++HFADL A LN  E  +L +LL Y
Sbjct: 2    MEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQY 61

Query: 61   GPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLHGIKRLERGTAYYVEAETALT 120
            GP +  H P G LLLVTPRPGTISPWSSKATDIAHNCGL  + RLERG AYY+EA T LT
Sbjct: 62   GPALSSHTPAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEAST-LT 120

Query: 121  AAQIATLEALLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGRRALEEANVSLGL 180
            A Q   + A LHDRMME VF+ LTDA++LF   +PAP+S VD+L  GR+AL +AN+ LGL
Sbjct: 121  AEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGL 180

Query: 181  ALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKM 240
            ALAEDEIDYL E+FTKLGRNPNDIEL MFAQANSEHCRHKIFNADW IDG  Q KSLFKM
Sbjct: 181  ALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKM 240

Query: 241  IKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYHHEDAHILMKVETHNHPT 300
            IKNTFE TPDYVLSAYKDNAAVM GS VGR+F D  + +Y +H E AHILMKVETHNHPT
Sbjct: 241  IKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPT 300

Query: 301  AISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPSRIV 360
            AISPWPGA+TGSGGEIRDEGATG G KPKAGLVGF+ SNLRIPGFEQPWE DFGKP RIV
Sbjct: 301  AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV 360

Query: 361  NALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNI 420
             ALDIM EGPLGGAAFNNEFGRP L GYFRTYEEKV SH GEE+RGYHKPIM+AGG+GNI
Sbjct: 361  TALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI 420

Query: 421  RAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERR 480
            RA+H+QK EI VGAKLIVLGGPAMNIGLGGGAASSMASGQS  DLDFASVQR+NPEMERR
Sbjct: 421  RADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR 480

Query: 481  CQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPL 540
            CQEVIDRCWQLGD NPI FIHDVGAGG+SNA+PELV+DG RGGKF+LR++ +DEPGMSPL
Sbjct: 481  CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL 540

Query: 541  EIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDM 600
            EIWCNESQERYVLAVAA+ +PLFD +C+RERAPYAV+G+ATEE+HL+L D+HF N PID+
Sbjct: 541  EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDL 600

Query: 601  PMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRVLRLPAVAEKTFLITIGDRSV 660
            P+D+LLGK PKM R+  TLK    AL R+ I + +AV RVL LP VAEKTFL+TIGDR+V
Sbjct: 601  PLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTIGDRTV 660

Query: 661  TGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAI 720
            TG+VARDQMVGPWQVPVA+CAVT AS DSY+GEAMS+GER PVALLDF ASARLAVGEA+
Sbjct: 661  TGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEAL 720

Query: 721  TNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKDSMS 780
            TNIAAT IG++KRIKLSANWM+ AGHPGEDAGLY+AVKAVGEELCP LG+TIPVGKDSMS
Sbjct: 721  TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMS 780

Query: 781  MKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRL 840
            MKT+WQE  EQ+E+TSPLSL+I+AFARVED+R T+TPQL T+  + +L+LIDLG G N L
Sbjct: 781  MKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTE--DNALLLIDLGKGHNAL 838

Query: 841  GATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMA 900
            GATALAQVY+QLGDKPADV + AQLKGF+DA+Q LV   KL+A+HD+ DGGLLVTLAEMA
Sbjct: 839  GATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTLAEMA 898

Query: 901  FAGHCGIKANIETLGDDALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHVIGEV 960
            FAGHCG++ +I  LGDD LAALFNEELG V+QV+ ++ +AV A LA +GL  C H +G+ 
Sbjct: 899  FAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHYLGQA 958

Query: 961  EASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDPGLN 1020
             A DR +IT  ++ +   SRT LR  WAE T +MQ LRDN  CADQE  AK ++ DPGLN
Sbjct: 959  LAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTDPGLN 1018

Query: 1021 AKLTYDVQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTG 1080
             KL++D+  D+AAPYIA G RPK+A+LREQGVNSHVEMAAAF RAGFDA+DVHMSD+L G
Sbjct: 1019 VKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGG 1078

Query: 1081 QTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGC 1140
            +  L  +  LVACGGFSYGDVLGAGEGWAKSILFN + R++FE FF R  T +LGVCNGC
Sbjct: 1079 RIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGC 1138

Query: 1141 QMLSNLRDLIPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVSHGE 1200
            QM+SNLR+LIPG+ELWPRFVRN SDRFEARFSLVEV +SPSL    M GS+MPIAVSHGE
Sbjct: 1139 QMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGE 1198

Query: 1201 GRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMM 1260
            GRVEVRD  HLAA+E  G VA+R+VDNFG+ T+ YP+NPNGSPN IT +TT++GRVTIMM
Sbjct: 1199 GRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMM 1258

Query: 1261 PHPERVFRTVANSWHPDNWGENGAWMRMFQNARKYFG 1297
            PHPERVFRTVANSWHP+NWGE+  WMR+F+NARK  G
Sbjct: 1259 PHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG 1295