Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 1295 a.a., phosphoribosylformylglycinamidine synthase, single chain form from Enterobacter asburiae PDN3

 Score = 1974 bits (5114), Expect = 0.0
 Identities = 963/1297 (74%), Positives = 1101/1297 (84%), Gaps = 3/1297 (0%)

Query: 1    MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTY 60
            M ILRGSPALS FR+ KLL   +   LPV+ IYAE++HFADL A LN +E  +LE+LL Y
Sbjct: 2    MEILRGSPALSAFRITKLLARFQAADLPVSNIYAEYVHFADLNAPLNAEERVQLERLLKY 61

Query: 61   GPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLHGIKRLERGTAYYVEAETALT 120
            GP++  H P G L+L TPRPGTISPWSSKATDIAHNCGL+ I RLERG AYYVEA T L+
Sbjct: 62   GPSLSSHTPTGKLILATPRPGTISPWSSKATDIAHNCGLNQINRLERGVAYYVEAST-LS 120

Query: 121  AAQIATLEALLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGRRALEEANVSLGL 180
             AQ   + A LHDRMME VFA L DAQ+LFS  +PAP+  VD+L  GR+AL +AN+ LGL
Sbjct: 121  EAQWQAVAAELHDRMMESVFASLDDAQKLFSHHQPAPVQSVDLLGQGRQALIDANLRLGL 180

Query: 181  ALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKM 240
            ALAEDEIDYL ++F KL RNPNDIEL MFAQANSEHCRHKIFNADW IDG +Q KSLFKM
Sbjct: 181  ALAEDEIDYLQDAFVKLNRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM 240

Query: 241  IKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYHHEDAHILMKVETHNHPT 300
            IKNT EQTPD+VLSAYKDNAAVM GS VGRFF D E+ +Y +H E AHILMKVETHNHPT
Sbjct: 241  IKNTMEQTPDHVLSAYKDNAAVMEGSEVGRFFADREAGRYDFHQEPAHILMKVETHNHPT 300

Query: 301  AISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPSRIV 360
            AISPWPGA+TGSGGEIRDEGATG G KPKAGLVGF+ SNLRIPGFEQPWE DFGKP RIV
Sbjct: 301  AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV 360

Query: 361  NALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNI 420
             ALDIM EGPLGGAAFNNEFGRP L GYFRTYEEKV SH GEE+RGYHKPIM+AGG+GNI
Sbjct: 361  TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVDSHNGEELRGYHKPIMLAGGIGNI 420

Query: 421  RAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERR 480
            RA+H+QK EI VGAKLIVLGGPAMNIGLGGGAASSMASGQS  DLDFASVQR+NPEMERR
Sbjct: 421  RADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR 480

Query: 481  CQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPL 540
            CQEVIDRCWQLGD NPI FIHDVGAGG+SNA+PELV+DG RGG+F LR++ +DEPGMSPL
Sbjct: 481  CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGRFNLRDILSDEPGMSPL 540

Query: 541  EIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDM 600
            EIWCNESQERYVLAVAA+ +PLFD +C+RERAPYAV+GEATEE HL+L D+HF N PID+
Sbjct: 541  EIWCNESQERYVLAVAADQLPLFDELCRRERAPYAVIGEATEELHLSLSDTHFDNQPIDL 600

Query: 601  PMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRVLRLPAVAEKTFLITIGDRSV 660
            P+D+LLGK PKM R+ +T K +  AL+R GI + EAV+RVL LPAVAEKTFL+TIGDR+V
Sbjct: 601  PLDVLLGKTPKMTRDVTTRKAAGKALDRQGITVAEAVNRVLHLPAVAEKTFLVTIGDRTV 660

Query: 661  TGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAI 720
            TG+V+RDQMVGPWQ+PVANCAVT AS DSY+GEAM++GERTPVALLDF ASARLAVGEA+
Sbjct: 661  TGMVSRDQMVGPWQIPVANCAVTTASLDSYYGEAMALGERTPVALLDFAASARLAVGEAL 720

Query: 721  TNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKDSMS 780
            TNIAAT IG++KRIKLSANWM+ AGHPGEDAGLYEAVKAVGEELCPALG+TIPVGKDSMS
Sbjct: 721  TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS 780

Query: 781  MKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRL 840
            MKT+WQE  EQ+E+TSPLSL+ITAFARVED+R TVTPQL T+  + +L+LIDLG G N L
Sbjct: 781  MKTRWQEGSEQREMTSPLSLVITAFARVEDVRHTVTPQLATE--DNALLLIDLGKGHNAL 838

Query: 841  GATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMA 900
            GATALAQVY+QLGDKPADV + AQLKGF+DA+Q LV   KL+AYHD+ DGGLLVTLAEMA
Sbjct: 839  GATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMA 898

Query: 901  FAGHCGIKANIETLGDDALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHVIGEV 960
            F GHCG++ANI TLG+D LAALFNEELGAV+QV+  + +AV A LA HGL  C H +G+ 
Sbjct: 899  FTGHCGVEANIATLGEDRLAALFNEELGAVIQVRAADRDAVEAILAKHGLADCVHYLGKA 958

Query: 961  EASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDPGLN 1020
               DR +I      +   SRT LR  WAE T +MQ LRDN  CADQE  AK +++DPGLN
Sbjct: 959  VQGDRFVIEADGHAVFSESRTTLRMWWAETTWQMQRLRDNPECADQEHNAKANDQDPGLN 1018

Query: 1021 AKLTYDVQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTG 1080
             KL++D+  D+AAPYIA G RPK+A+LREQGVNSHVEMAAAF RAGFDA+DVHMSD+L G
Sbjct: 1019 VKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAG 1078

Query: 1081 QTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGC 1140
            +T L+ +Q LVACGGFSYGDVLGAGEGWAKSILFN++ R++FE FF R  T +LGVCNGC
Sbjct: 1079 RTGLEDFQALVACGGFSYGDVLGAGEGWAKSILFNSRVRDEFETFFHRPQTLALGVCNGC 1138

Query: 1141 QMLSNLRDLIPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVSHGE 1200
            QM+SNLR+LIPG+E WPRFVRN+SDRFEARFSLVEV +SPSL    M GS+MPIAVSHGE
Sbjct: 1139 QMMSNLRELIPGSEAWPRFVRNQSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGE 1198

Query: 1201 GRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMM 1260
            G+VEVRDA HLA +E  G VA+RFVDNFG+ T+ YP+NPNGS N IT +T++ GR TIMM
Sbjct: 1199 GQVEVRDAAHLAQLESKGLVALRFVDNFGKVTETYPANPNGSANGITAVTSESGRATIMM 1258

Query: 1261 PHPERVFRTVANSWHPDNWGENGAWMRMFQNARKYFG 1297
            PHPERVFRTV+NSWHP+NWGE+  WMR+F+NARK  G
Sbjct: 1259 PHPERVFRTVSNSWHPENWGEDSPWMRIFRNARKQLG 1295