Pairwise Alignments

Query, 1297 a.a., phosphoribosylformylglycinamidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 1295 a.a., phosphoribosylformylglycinamidine synthase from Escherichia coli ECRC62

 Score = 1980 bits (5129), Expect = 0.0
 Identities = 967/1297 (74%), Positives = 1097/1297 (84%), Gaps = 3/1297 (0%)

Query: 1    MRILRGSPALSEFRVNKLLTACREQQLPVTGIYAEFMHFADLKAELNPQELEKLEKLLTY 60
            M ILRGSPALS FR+NKLL   +  +LPV  IYAE++HFADL A LN  E  +LE+LL Y
Sbjct: 2    MEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKY 61

Query: 61   GPTIQEHEPQGLLLLVTPRPGTISPWSSKATDIAHNCGLHGIKRLERGTAYYVEAETALT 120
            GP +  H PQG LLLVTPRPGTISPWSSKATDIAHNCGL  + RLERG AYY+EA T LT
Sbjct: 62   GPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGT-LT 120

Query: 121  AAQIATLEALLHDRMMEVVFAELTDAQQLFSVAEPAPMSQVDVLAGGRRALEEANVSLGL 180
              Q   + A LHDRMME VF  L DA+QLF+  +P P++ VD+L  GR+AL +AN+ LGL
Sbjct: 121  NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL 180

Query: 181  ALAEDEIDYLVESFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVKQDKSLFKM 240
            ALAEDEIDYL ++FTKLGRNPNDIEL MFAQANSEHCRHKIFNADW IDG +Q KSLFKM
Sbjct: 181  ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKM 240

Query: 241  IKNTFEQTPDYVLSAYKDNAAVMTGSTVGRFFPDPESRQYTYHHEDAHILMKVETHNHPT 300
            IKNTFE TPDYVLSAYKDNAAVM GS VGR+F D E+ +Y +H E AHILMKVETHNHPT
Sbjct: 241  IKNTFETTPDYVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT 300

Query: 301  AISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWESDFGKPSRIV 360
            AISPWPGA+TGSGGEIRDEGATG G KPKAGLVGF+ SNLRIPGFEQPWE DFGKP RIV
Sbjct: 301  AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV 360

Query: 361  NALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIAGGMGNI 420
             ALDIM EGPLGGAAFNNEFGRP L GYFRTYEEKV SH GEE+RGYHKPIM+AGG+GNI
Sbjct: 361  TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI 420

Query: 421  RAEHIQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERR 480
            RA+H+QK EI VGAKL+VLGGPAMNIGLGGGAASSMASGQS  DLDFASVQR+NPEMERR
Sbjct: 421  RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR 480

Query: 481  CQEVIDRCWQLGDKNPIAFIHDVGAGGISNALPELVNDGDRGGKFQLRNVPNDEPGMSPL 540
            CQEVIDRCWQLGD NPI FIHDVGAGG+SNA+PELV+DG RGGKF+LR++ +DEPGMSPL
Sbjct: 481  CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL 540

Query: 541  EIWCNESQERYVLAVAAEDMPLFDAICQRERAPYAVVGEATEERHLTLEDSHFANTPIDM 600
            EIWCNESQERYVLAVAA+ +PLFD +C+RERAPYAV+GEATEE HL+L D HF N PID+
Sbjct: 541  EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL 600

Query: 601  PMDILLGKPPKMHREASTLKVSSPALERSGIELNEAVDRVLRLPAVAEKTFLITIGDRSV 660
            P+D+LLGK PKM R+  TLK    AL R GI + +AV RVL LP VAEKTFL+TIGDRSV
Sbjct: 601  PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV 660

Query: 661  TGLVARDQMVGPWQVPVANCAVTAASFDSYHGEAMSMGERTPVALLDFGASARLAVGEAI 720
            TG+VARDQMVGPWQVPVANCAVT AS DSY+GEAM++GER PVALLDF ASARLAVGEA+
Sbjct: 661  TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL 720

Query: 721  TNIAATDIGELKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGITIPVGKDSMS 780
            TNIAAT IG++KRIKLSANWM+ AGHPGEDAGLYEAVKAVGEELCPALG+TIPVGKDSMS
Sbjct: 721  TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS 780

Query: 781  MKTKWQENGEQKEVTSPLSLIITAFARVEDIRKTVTPQLRTDLGETSLILIDLGNGQNRL 840
            MKT+WQE  E++E+TSPLSL+I+AFARVED+R T+TPQL T+  + +L+LIDLG G N L
Sbjct: 781  MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTE--DNALLLIDLGKGNNAL 838

Query: 841  GATALAQVYKQLGDKPADVDNAAQLKGFFDAVQTLVRNDKLVAYHDKGDGGLLVTLAEMA 900
            GATALAQVY+QLGDKPADV + AQLKGF+DA+Q LV   KL+AYHD+ DGGLLVTLAEMA
Sbjct: 839  GATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMA 898

Query: 901  FAGHCGIKANIETLGDDALAALFNEELGAVVQVKNDELNAVLATLAAHGLEACAHVIGEV 960
            FAGHCGI A+I +LGDD LAALFNEELGAV+QV+  +  AV + LA HGL  C H +G+ 
Sbjct: 899  FAGHCGINADIASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQA 958

Query: 961  EASDRLLITCGEEVLIERSRTELRTIWAEMTHKMQALRDNSACADQEFAAKQDNRDPGLN 1020
             + DR +IT   + +   SRT LR  WAE T +MQ LRDN  CADQE  AK ++ DPGLN
Sbjct: 959  VSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLN 1018

Query: 1021 AKLTYDVQADVAAPYIAKGVRPKMAILREQGVNSHVEMAAAFDRAGFDAVDVHMSDILTG 1080
             KL++D+  DVAAPYIA G RPK+A+LREQGVNSHVEMAAAF RAGFDA+DVHMSD+L G
Sbjct: 1019 VKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAG 1078

Query: 1081 QTVLDAYQGLVACGGFSYGDVLGAGEGWAKSILFNAQAREQFEQFFQRKDTFSLGVCNGC 1140
            +T L+ +  LVACGGFSYGDVLGAGEGWAKSILFN + R++F  FF R  T +LGVCNGC
Sbjct: 1079 RTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGC 1138

Query: 1141 QMLSNLRDLIPGAELWPRFVRNESDRFEARFSLVEVQKSPSLFFSEMAGSRMPIAVSHGE 1200
            QM+SNLR+LIPG+ELWPRFVRN SDRFEARFSLVEV +SPSL    M GS+MPIAVSHGE
Sbjct: 1139 QMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGE 1198

Query: 1201 GRVEVRDAQHLAAIEQSGTVAIRFVDNFGQPTQAYPSNPNGSPNAITGLTTQDGRVTIMM 1260
            GRVEVRDA HLAA+E    VA+R+VDNFG+ T+ YP+NPNGSPN IT +TT+ GRVTIMM
Sbjct: 1199 GRVEVRDAAHLAALESKVLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMM 1258

Query: 1261 PHPERVFRTVANSWHPDNWGENGAWMRMFQNARKYFG 1297
            PHPERVFRTV+NSWHP+NWGE+G WMR+F+NARK  G
Sbjct: 1259 PHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG 1295