Pairwise Alignments

Query, 543 a.a., 2,3-dihydroxybenzoate-AMP ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 536 a.a., (2,3-dihydroxybenzoyl)adenylate synthase EntE from Escherichia coli ECRC100

 Score =  504 bits (1298), Expect = e-147
 Identities = 258/535 (48%), Positives = 355/535 (66%), Gaps = 10/535 (1%)

Query: 1   MTTDFTPWPEALAAQYRQLGYWQDKTLLDYLQQSAERTPNALALVGDNQQWRYQAMLERI 60
           M+  FT WPE  A +YR+ GYWQD  L D L + A    +++A++   +Q  Y+ + +  
Sbjct: 1   MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHA--ASDSIAVIDGERQLSYRELNQAA 58

Query: 61  EQLAAGFTELGLGCGDNVVLQLGNVAEFYLCFFALLRQGIRPILALPAHRLAEIRYFCQH 120
           + LA      G+  G+  ++QLGNVAE Y+ FFALL+ G+ P+LAL +H+ +E+  +   
Sbjct: 59  DNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQ 118

Query: 121 SQAKAYLIDGAQRPFDYQALAQELLACCPTLQTVIVRGQTRVTDPKFIELASCYSASSCQ 180
            +    + D     F         +A   +++ V +   +   +   ++ A  + A    
Sbjct: 119 IEPALLIADRQHALFSGDDFLNTFVAEHSSIRVVQLLNDSGEHN---LQDAINHPADGFT 175

Query: 181 ANADP-NQIAFFQLSGGTTGTPKLIPRTHNDYAYSVTASVEICRFDQHTRYLCVLPAAHN 239
           A   P +++ +FQLSGGTTGTPKLIPRTHNDY YSV  SVEIC+F Q TRYLC +PAAHN
Sbjct: 176 ATPSPADEVVYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHN 235

Query: 240 FPLSSPGALGVFWAGGCVVLSQDASPQHAFKLIEQHKITVTALVPPLALLWMDHAEK--S 297
           + +SSPG+LGVF AGG VVL+ D S    F LIE+H+I VTALVPP   LW+    +  S
Sbjct: 236 YAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQINVTALVPPAVSLWLQALTEGES 295

Query: 298 TYDLSSLHFVQVGGAKFSEAAARRLPKALGCQLQQVFGMAEGLVNYTRLDDSAELIATTQ 357
              L+SL  +QVGGA+ S   A R+P  +GCQLQQVFGMAEGLVNYTRLDDSAE I  TQ
Sbjct: 296 RAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQ 355

Query: 358 GRPISAHDQLLVVDEQGQPVASGEEGYLLTQGPYTIRGYYRADQHNQRAFNAQGFYITGD 417
           G P+   D++ V D +G P+  GE G L+T+GPYT RGYY++ QHN  AF+A GFY +GD
Sbjct: 356 GYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSGD 415

Query: 418 KVKLSSEGYVIVTGRAKDQINRGGEKIAAEEVENQLLHHPAVHDAALIAISDEYLGERSC 477
            + +  EGY+ V GR KDQINRGGEKIAAEE+EN LL HPAV  AAL+++ DE +GE+SC
Sbjct: 416 LISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSC 475

Query: 478 AVIVLKPEQSVNTIQLKRFLHQAGLADYKIPDQIQFIDQLPKTSVGKIDKNALRR 532
           A +V+K  + +  +Q++RFL + G+A++K+PD+++ +D LP T+VGK+DK  LR+
Sbjct: 476 AYLVVK--EPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQ 528