Pairwise Alignments

Query, 487 a.a., IMP dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 489 a.a., Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain from Variovorax sp. SCN45

 Score =  583 bits (1504), Expect = e-171
 Identities = 286/488 (58%), Positives = 378/488 (77%), Gaps = 5/488 (1%)

Query: 2   LRIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIAL 61
           +R+  +ALTFDDVLLVPA S VLP    L T+L++NI LN+P++SA+MDTVTEARLAIA+
Sbjct: 1   MRLLGKALTFDDVLLVPAFSQVLPKDTSLATKLSRNITLNLPLISAAMDTVTEARLAIAI 60

Query: 62  AQEGGIGFIHKNMSIEQQAAQVHQVKIFEAGVVTHPVTVRPEQTIADVMELTHYHGFAGF 121
           AQEGG+G +HKN++ +QQAA+V +VK +E+GV+  PV + P  ++  VM L+   G +GF
Sbjct: 61  AQEGGMGIVHKNLTAQQQAAEVARVKRYESGVLRDPVVITPTHSVRQVMALSDQLGISGF 120

Query: 122 PVVTENNELVGIITGRDVRFVTDLTKSVAAVMTPKERLATVKEGATGAEVQEKMHKARVE 181
           PVV +  ++VGI+TGRD+RF       V+ +MT +E+L TV +G T AE +  ++K ++E
Sbjct: 121 PVV-DAGKVVGIVTGRDLRFENRYDVPVSEIMTRREKLITVPDGTTLAEAKALLNKYKLE 179

Query: 182 KILVVNDEFQLKGMITAKDFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEAG 241
           ++LV+N +++LKG+IT KD  K  S PNA +D  GRLRVGAAVG   G EERV+ALV+AG
Sbjct: 180 RLLVINGDWELKGLITVKDITKQTSFPNAARDANGRLRVGAAVGVGDGTEERVEALVKAG 239

Query: 242 VDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGP 301
           VD +++D++HGHS GV++R+R  +  YP +++IGGN+AT + ARAL + G  AVKVGIGP
Sbjct: 240 VDAIVVDTAHGHSAGVIERVRWVKKNYPQVDVIGGNIATGDAARALADVGADAVKVGIGP 299

Query: 302 GSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVG 361
           GSICTTRIV GVGVPQI A+   A      GIP+I+DGG+R+SGDI+KAIAAGAS VM+G
Sbjct: 300 GSICTTRIVAGVGVPQIMAVDSVATALQGTGIPLISDGGVRYSGDIAKAIAAGASTVMMG 359

Query: 362 SMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSKGSSDRYFQTDNA----ADKLVPEGI 417
           SMFAGTEEAPGE++LYQGRSYK+YRGMGS+GAM +GS+DRYFQ         DKLVPEGI
Sbjct: 360 SMFAGTEEAPGEIVLYQGRSYKSYRGMGSIGAMQQGSADRYFQESTTGNPNTDKLVPEGI 419

Query: 418 EGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTKAQFVRISGAGMKESHVHDVQI 477
           EGR+ YKG +  I++Q  GG+R+ MG  G AT+ D++ KA+FV I+ AG++ESHVHDVQI
Sbjct: 420 EGRVPYKGSIVSIVYQMAGGVRASMGYCGCATIADMQNKAEFVEITTAGIRESHVHDVQI 479

Query: 478 TKEAPNYR 485
           TKEAPNYR
Sbjct: 480 TKEAPNYR 487