Pairwise Alignments

Query, 1039 a.a., AcrB/AcrD/AcrF family protein from Vibrio cholerae E7946 ATCC 55056

Subject, 1051 a.a., The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family from Enterobacter asburiae PDN3

 Score =  271 bits (693), Expect = 2e-76
 Identities = 249/1055 (23%), Positives = 468/1055 (44%), Gaps = 78/1055 (7%)

Query: 9    LSRTRTMLTLLVFILVAGVATYLTIPKESSPDVTIPIIYVSVSHQGISPSDAERLIVRPL 68
            + R R  + + + I + G      IP E  P +  P++ VS S  G S +D    I  PL
Sbjct: 6    IKRPRFAMVIALVITLVGAIALRIIPVEQYPQIAPPVVNVSASWPGASSTDVAEAIATPL 65

Query: 69   EQEMRSIEGVKEMTATAS-EGHASVVLEFNVGVDLAKAMADVRDAVDLAKPKLPADSDEP 127
            E ++  ++ +  M +T+S EG  S+ + F  G D   A  DV++ V  A  +LP ++ + 
Sbjct: 66   ETQLNGVDHMLYMESTSSDEGTYSLNITFAAGTDPDLAAIDVQNRVAQAVAQLPTEAQQN 125

Query: 128  TVNEVTLAAEQPVLSVVLYGTVPERTTVLIAR----QLRDKLESFRQILSVDIAGDREEI 183
             V +V   A   ++ V LY      T + ++     Q+R+ L     +  V + G R+  
Sbjct: 126  GV-QVRKRATNLMMGVSLYSPNNTHTPLFVSNYASTQVREALSRLPGVGQVQMFGARDYS 184

Query: 184  VEIIVDPLLMESYGLDQSDIYNLIALNNRVVAAGFVDT--------------GYGRFSVK 229
            + I + P  M +  +   D+   +   N   AAG V T              G GR S  
Sbjct: 185  MRIWLRPDRMNALNVTTDDVAQALREQNVQGAAGQVGTPPVFNGQQQTLTINGLGRLS-- 242

Query: 230  VPSVFESLKDVLELPIKV-EGKQVITFGDVATVRKSFRDPESFARLDGKPAIVLDIKKRS 288
                    +D  ++ I+  E  Q++   DVAT+    R   S ARL+G  +  L I    
Sbjct: 243  ------QAEDFADIIIRAGEMGQLVRLKDVATIELGSRSYSSGARLNGHDSAYLGIYPTP 296

Query: 289  GENIIETVELVKAVLGEAQARDDWPNNLLVKTIWDESEDVKLMLNDLQNNILSAIILVVV 348
              N +   + V+A L     R  +P++L+ +  +D +  V   + ++  ++   ++ VVV
Sbjct: 297  SANALRVADAVRAELERLSTR--FPDDLVYEVKFDTTSFVAATIKEIGVSLALTLLAVVV 354

Query: 349  VIIAIL-GVRTSLLVGVSIPGSFLTGLLVLAVFGLTVNIVVLFALIMAVGMLVDGAIVVT 407
            V+   L   R +L+V ++IP S +    VL   G + N + LFA+I+A+ M+VD AIVV 
Sbjct: 355  VVSLFLQSWRATLIVALAIPVSLVGTFAVLYTLGYSANTLSLFAIILALTMVVDDAIVVV 414

Query: 408  EFADRRMQEGMHRSEAYRDAAKRMAWPITASTATTLAAFAPLLFWPDVTGEFMKYLPLTL 467
            E  +  M EG  R+ A   A +++A P+ A+T   LA F P+   P + GE  +   +TL
Sbjct: 415  ESVETLMAEGQSRTAATALALRQIAGPVIATTLVLLAVFVPVALLPGIVGELYRQFAVTL 474

Query: 468  MATLTASLVMALLFVPVLGSLFGRPQKVTQANQARMVALHNGDFSQATGITKAYYSTLAI 527
               +T S ++AL   P L ++  RP+    A   R        F++    T+ +Y+ +  
Sbjct: 475  STAVTLSSLVALTLTPALCAMLLRPRPEKPAAVYRA-------FNRGMDATRGFYTRIVH 527

Query: 528  AIR-HPIKILCGALLMSAAIAFAYGKAGLGAEFFPEVDPPFFSVKVRSYGDLSLNEKDRI 586
             +   P   L      +A +AF++    +   F P+ D  +F   V+     SL   + +
Sbjct: 528  VLNLRPWLALLATAGAAAVVAFSF--TSMPKSFLPQEDQGYFFASVQLPEAASLERTEAV 585

Query: 587  MSDIEQVMLGHDEFESVYTRTG-------GDDEIGVVQITPVDWQYRRSVKAIIEELEQV 639
            M+   +++  +   E V   +G            G + I   DW  R  +  ++  L++ 
Sbjct: 586  MNTARELIAKNPAVEDVIQVSGFNILNGTSASNGGFISIMLKDWSERPPLDEVMGTLQRQ 645

Query: 640  TDTFPGVEI----EYKFPDAGPPVEHDLEIEISA-RVADDLDKAAQQVRLWAEANPALTN 694
                P   I        P  G     DL I+  A +   +L++  ++V   A  +P L+ 
Sbjct: 646  LLALPEATIMTFAPPTLPGLGNASGFDLRIQAQAGQSPAELERVTREVLAKANQHPQLSR 705

Query: 695  LSDNGSKPGIDWKIDIRRDDASRFAADATLVGNTVQFVTNGLKIGDYLPDDSDEEVDILV 754
            +    S       + + R+ A+R     + + +++Q    G + GD+    ++    +++
Sbjct: 706  VFTTWSSNVPQLTLTVDRERAARLDVPVSRIFSSLQTAFGGTRAGDF--SVNNRVYHVVM 763

Query: 755  RYPSEYRD-IGRFDQLRVKTAQG-LVPLTNFAQIIPEQKQDTIHRVDGRRVISVMADLKE 812
            +   ++R+   +  +L V++  G  V L+N   I P      + + +    +SV      
Sbjct: 764  QNEMQWRERAEQISELFVRSNSGERVRLSNLVTITPSVGAPFLQQYNQFPSVSVSGSAAA 823

Query: 813  GYNLALELPAIEQALRELNLPSSVEFRIRGQNEEQEHSAVFLEKAFMVALAAMA---IIL 869
            G + +  + A+ + L E NLP+  ++   G + +++ +     +A  + LAA+    + L
Sbjct: 824  GVSSSTAMAAMGEILAE-NLPAGYDYAWSGMSYQEQQTG---NQAIWIVLAAVVMAWLFL 879

Query: 870  ITQFNSFYQAFLILTAVIFSTVGVFAGLLIFQKPFGIIMSGIGVIALAGIVVNNNIVLID 929
            + Q+ S+     ++ +V+F+  G    L +      + +  IG++ L  +   N I++++
Sbjct: 880  VAQYESWTLPASVMLSVLFAIGGALVWLWMAGYANDVYVQ-IGLVLLIALAAKNAILIVE 938

Query: 930  TYNQLLKRGLSREEAILRTGVQRLRPVLLTTVTTILGLLPMVLEMNIDIINQKIEFGAPS 989
                    G++  +A      +R R V++T V+ I+G+LPM+L       +++I      
Sbjct: 939  FARARRMDGMAIVDAAREGASRRFRAVMMTAVSFIIGVLPMMLATGAGAQSRRI------ 992

Query: 990  TQWWSQLATAVAGGLAFATVLTLVLTPCLLMLGRR 1024
                  + T V  G+  ATV+ ++  P L +L +R
Sbjct: 993  ------IGTTVFSGMLVATVVGILFIPALFVLFQR 1021