Pairwise Alignments

Query, 860 a.a., alanine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 875 a.a., alanyl-tRNA synthetase (EC 6.1.1.7) from Enterobacter asburiae PDN3

 Score = 1191 bits (3081), Expect = 0.0
 Identities = 602/876 (68%), Positives = 696/876 (79%), Gaps = 17/876 (1%)

Query: 1   MFMSTDEVRRAFLSFFESKGHQIVESSSLVPANDPTLLFTNAGMNQFKDCFLGLEKRAYT 60
           M  ST E+R+AFL FF SKGHQ+V SSSLVP NDPTLLFTNAGMNQFKD FLGL+KR Y+
Sbjct: 1   MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRNYS 60

Query: 61  RATTAQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKEDAIQYAWEFLT--DV 118
           RATT+QRCVRAGGKHNDLENVG+TARHHTFFEMLGNFSFGDYFK DAIQ AWE LT  + 
Sbjct: 61  RATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQNAWELLTGENW 120

Query: 119 LQLPKERLLVTVYETDDEAFDIWNKKVGIPADRIIRIGDKKGGKKFDSDNFWQMGDTGPC 178
             LPKERL VTVYETDDEA++IW K+VGIP +RIIRIGD KG   + SDNFWQMGDTGPC
Sbjct: 121 FNLPKERLWVTVYETDDEAYEIWEKEVGIPRERIIRIGDNKGAP-YASDNFWQMGDTGPC 179

Query: 179 GPCTEIFYDHGDHIWGGPPGSPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGM 238
           GPCTEIFYDHGDHIWGGPPGSPEEDGDR+IEIWN VFMQFNR ADGTMEPLPKPSVDTGM
Sbjct: 180 GPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGM 239

Query: 239 GIERISAIMQGVHSNYEIDVFQTLIKAAADAIGYQDLTNQSLRVVADHIRSCAFLIVDGV 298
           G+ERI+A++Q V+SNYEID+F TLIKA A+  G  DL N+SLRV+ADHIRSCAFLI DGV
Sbjct: 240 GLERIAAVLQHVNSNYEIDLFSTLIKAVANVTGATDLNNKSLRVIADHIRSCAFLIADGV 299

Query: 299 MPSNEGRGYVLRRIIRRAVRHGNKLGAQGAFFHKLVGPLAEVMGTAGVELKKQQALVEKV 358
           +PSNE RGYVLRRIIRRA+RHGN LGA+  FF+KLVGPL  VMG AG ELK+QQA VE+V
Sbjct: 300 IPSNENRGYVLRRIIRRAIRHGNMLGAKDTFFYKLVGPLIGVMGAAGDELKRQQAQVEQV 359

Query: 359 LRIEEENFGRTLDRGMSILNDALDQLSGQVLDGETVFKLYDTYGFPADLTNDVARERGFS 418
           L+ EEE F RTL+RG+++L++ L +L G  LDGET F+LYDTYGFP DLT DV RER   
Sbjct: 360 LKTEEEQFARTLERGLALLDEELAKLKGDTLDGETAFRLYDTYGFPVDLTADVCRERNIK 419

Query: 419 IDEAGFEQAMEEQRQRAREAGQFGTDYNSLIKSATNTEFCGYTASRGQSVVREMFVEGAE 478
           +DEAGFE AMEEQR+RARE+  FG DYN++I+  + +EF GY A      V  +FV+G  
Sbjct: 420 VDEAGFEAAMEEQRRRARESSGFGADYNAMIRVDSASEFKGYDALELTGKVTALFVDGKA 479

Query: 479 VSTLSAGDKAIIVLDNTPFYAESGGQCGDTGVLKTDAGIFHVEDTQKLGNAIAHHGVIAQ 538
           V ++SAG  A+++LD TPFYAESGGQ GD G LK +   F V DTQK G AI H G +  
Sbjct: 480 VDSISAGQDAVVILDKTPFYAESGGQVGDKGELKGNGFSFSVSDTQKYGQAIGHQGKLVS 539

Query: 539 GVLATGDQVDAIVDEKRRAAISLNHSATHLLHAALRKVLGEHVAQKGSLVRAETLRFDFS 598
           G L  G+ V A VDE RRA I LNHSATHL+HAALR VLG HVAQKGSLV  + LRFDFS
Sbjct: 540 GSLKVGEGVQANVDEARRARIRLNHSATHLMHAALRDVLGTHVAQKGSLVNDKVLRFDFS 599

Query: 599 HLEAMTAAEIKEVERLVNQEVRRNHSIETNIMNIDEAKAKGAMALFGEKYDDQVRVLSMG 658
           H EAM  +EI+ VE LVN ++RRN  IET+IM +++AK KGAMALFGEKYDD+VRVLSMG
Sbjct: 600 HFEAMKPSEIRAVEDLVNAQIRRNLPIETHIMELEDAKKKGAMALFGEKYDDRVRVLSMG 659

Query: 659 DFSTELCGGIHASNTGDIGLFKIISEGGIAAGIRRIEAVTGEGALDYLDAQQAQ-HD--- 714
           DFSTELCGG HAS TGDIGLF+I+SE G AAG+RRIEAVTGEGA+  L AQ  Q HD   
Sbjct: 660 DFSTELCGGTHASRTGDIGLFRIVSESGTAAGVRRIEAVTGEGAIASLHAQSDQLHDIAQ 719

Query: 715 ----------AKVSEMAAKAKLLEKEIQQLKDKLAAKESAGLINQVKQIAGVNVLVAQLN 764
                      KV     + + LEKE+QQLK++ AA+ESA L ++   I GV +LV+ L 
Sbjct: 720 LLKGDSQNLGEKVRVALDRTRQLEKELQQLKEQAAAQESANLSSKAVDIKGVKLLVSDLA 779

Query: 765 GADNKALRGMVDDLKNQLSSGIIMLGNVAEGKVGLIAGVTNDLTNKVKAGELVNMVALQV 824
           G + K LR MVDDLKNQL S +I+L  VAEGKV LIAGV+ D+T++VKAGEL+ MVA QV
Sbjct: 780 GVEPKMLRTMVDDLKNQLGSTVIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQV 839

Query: 825 GGKGGGRPDMAQAGGTDAHALPSALESVDAWIAERL 860
           GGKGGGRPDMAQAGGTDA ALP AL SV++W++ +L
Sbjct: 840 GGKGGGRPDMAQAGGTDAAALPQALASVESWVSAKL 875