Pairwise Alignments

Query, 470 a.a., pyruvate kinase PykF from Vibrio cholerae E7946 ATCC 55056

Subject, 480 a.a., pyruvate kinase (NCBI) from Escherichia coli BW25113

 Score =  295 bits (754), Expect = 3e-84
 Identities = 180/474 (37%), Positives = 272/474 (57%), Gaps = 9/474 (1%)

Query: 1   MKKTKIVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQ 60
           +++TKIV T+GP T+    L +++ AG NV+R+NFSHG   +H  R    R++    G+ 
Sbjct: 5   LRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRH 64

Query: 61  LAILLDTKGPEIRTIKLENGDDVDLVAGQEFTFTTDT-KVVGNKERVAVTYSGFAKDLNV 119
           +AIL D +GP+IR    + G  V L  G +F    +  K  G+KE+V + Y G   D+  
Sbjct: 65  VAILGDLQGPKIRVSTFKEGK-VFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVP 123

Query: 120 GNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSEKDKNDLK 179
           G+ +L+DDG ++++VL     +V  +V   G L  NKG+N  G  ++  AL+EKDK D+K
Sbjct: 124 GDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIK 183

Query: 180 FGCEQGVDFVAASFIRKGSDVKEIREVLASHGGQNIQIISKIENQEGL---DNFDEILEL 236
                GVD++A SF R G D+   R  LA   G + +I++K+E  E +   D  D+I+  
Sbjct: 184 TAALIGVDYLAVSFPRCGEDLNYARR-LARDAGCDAKIVAKVERAEAVCSQDAMDDIILA 242

Query: 237 SDGIMVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAG 296
           SD +MVARGDLGVEI   E++  QK +I +  +  + VITATQM++SMI NP PTRAE  
Sbjct: 243 SDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVM 302

Query: 297 DVANAIMDGTDAVMLSGETAKGKYPVEAVKIMAQIAERTDPVLKAELGS-RLDSPRLRIT 355
           DVANA++DGTDAVMLS ETA G+YP E V  MA++    + +    +   RLD     + 
Sbjct: 303 DVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKIPSINVSKHRLDVQFDNVE 362

Query: 356 EAVCKGAVDTAEKL-AAPLIIVATEAGKSARSVRKYFPTANIIAVTTNKKTAAQLVLSKG 414
           EA+   A+  A  L     II  TE+G++A    +      I A++ +++T     L +G
Sbjct: 363 EAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAMSRHERTLNLTALYRG 422

Query: 415 VTPVVVDAIDNTDAFYHLGKEIALQSGLGKKGDIVVMVSGALVAS-GTTNTASV 467
           VTPV  D+ ++  A       +    G    GD+V++  G ++++ G+TNT  +
Sbjct: 423 VTPVHFDSANDGVAAASEAVNLLRDKGYLMSGDLVIVTQGDVMSTVGSTNTTRI 476