Pairwise Alignments

Query, 451 a.a., lysine-sensitive aspartokinase 3 from Vibrio cholerae E7946 ATCC 55056

Subject, 810 a.a., bifunctional aspartate kinase/homoserine dehydrogenase II from Escherichia coli ECRC62

 Score =  120 bits (302), Expect = 1e-31
 Identities = 120/462 (25%), Positives = 208/462 (45%), Gaps = 39/462 (8%)

Query: 8   KFGGTSVANFEAMSRCSAIIE--NNPQTRLVVSSACSGVTNLLVELANGVASTERRQA-- 63
           KFGG+S+A+ +   R + I+   + P   +VVS+A S  TN L+     ++ T+R  A  
Sbjct: 16  KFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGS-TTNQLINWLK-LSQTDRLSAHQ 73

Query: 64  ILQQLADIHYVIIDQLADPTRVEKEVKAVLDSVASAAEAASFQSSKKLTDHLVACGELIS 123
           + Q L      +I  L      +  + A +  +   A       +  +   +V  GE+ S
Sbjct: 74  VQQTLRRYQCDLISGLLPAEEADSLISAFVSDLERLAALLDSGINDAVYAEVVGHGEVWS 133

Query: 124 TYILTQLMRERGVDAVRFDIREVLRTDDHYGRAEPQLKEIAQ--LAKEKLVPLCEQYVVV 181
             +++ ++ ++G+ A   D RE LR +     A+PQ+ E     L ++ LV    + +VV
Sbjct: 134 ARLMSAVLNQQGLPAAWLDAREFLRAER---AAQPQVDEGLSYPLLQQLLVQHPGKRLVV 190

Query: 182 TQGFIGSDAQGNTTTLGRGGSDYSAALIAEAVQASGLEIWTDVPGIYSTDPRIAPKAAPI 241
           T GFI  +  G T  LGR GSDYSA  I      S + IW+DV G+YS DPR    A  +
Sbjct: 191 T-GFISRNNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADPRKVKDACLL 249

Query: 242 PEISFSEASEMANFGAKILHPSTLLPAVRHGIPVFVGSSKEPEKGGTWIRKQVESAPLYR 301
           P +   EASE+A   A +LH  TL P     I + +  S  P++G T I + + S    R
Sbjct: 250 PLLRLDEASELARLAAPVLHARTLQPVSGSEIDLQLRCSYTPDQGSTRIERVLASGTGAR 309

Query: 302 ALALRCNQTMVTLR--SAQMFH-AYGFLAKVFEILAKHKISV---------DLITTSEIS 349
            +    +  ++  +  ++Q F  A+  + ++ +      ++V             TSE++
Sbjct: 310 IVTSHDDVCLIEFQVPASQDFKLAHKEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVA 369

Query: 350 VSLTLDKTDTSGGAPELPEAVRAELEELCTVEVEYNLCLIALIGNKMKESRGYAKQVFSV 409
            S  L   D +G    LP  +R          +   L L+A++G  +  +  +  + +  
Sbjct: 370 DS-ALKILDEAG----LPGELR----------LRQGLALVAMVGAGVTRNPLHCHRFWQQ 414

Query: 410 LEDYNLRMICYGASAHNLCFLLHESVSKQAVQKLHKELFEQE 451
           L+   +          +L  +L    ++  +Q LH+ +F  E
Sbjct: 415 LKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQSVFRAE 456