Pairwise Alignments

Query, 653 a.a., DNA mismatch repair protein MutL from Vibrio cholerae E7946 ATCC 55056

Subject, 638 a.a., DNA mismatch repair protein from Pseudomonas simiae WCS417

 Score =  453 bits (1166), Expect = e-132
 Identities = 270/632 (42%), Positives = 364/632 (57%), Gaps = 46/632 (7%)

Query: 3   IRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNGSG 62
           I +L  RLANQIAAGEVVERPASV+KEL+ENS+D+GA RID+D+E+GG KL+R+RD+GSG
Sbjct: 12  IELLSPRLANQIAAGEVVERPASVIKELLENSIDSGAKRIDVDVEQGGVKLLRVRDDGSG 71

Query: 63  IDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEAWS 122
           I  D+L LAL+RHATSKI  L+DLE +MSLGFRGEALASISSV+RLTLTSRT + E+AW 
Sbjct: 72  ISSDDLPLALARHATSKIRDLEDLERVMSLGFRGEALASISSVARLTLTSRTRSAEQAWQ 131

Query: 123 AYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIALSR 182
             +EGRDMA ++QPAAHPVGT+VEV DLFFNTPARRKFL+ EKTEF H+ E++KR+AL+R
Sbjct: 132 VETEGRDMAPRVQPAAHPVGTSVEVRDLFFNTPARRKFLKAEKTEFDHLQEVIKRLALAR 191

Query: 183 FDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWITT 242
           FDV+F LRHNGK +     A     + +R++A+CG  F++  L IE+E  GL+L GW+  
Sbjct: 192 FDVAFHLRHNGKTILSLHEAHDDAARARRVSAICGPGFLEQALPIEIERNGLRLWGWVGL 251

Query: 243 PEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVDVNV 302
           P  +R Q+DLQY +VNGR +RDKL+ HA+RQ+Y   L   +  T+VLF E+DP  VDVNV
Sbjct: 252 PTFSRSQADLQYFFVNGRAVRDKLVAHAVRQAYRDVLFNGRHPTFVLFFEVDPSVVDVNV 311

Query: 303 HPAKHEVRFHQARLVHDFIYQALSSALVQ---GAQVMAPTINEGAFHLPHCAEEVNPPVV 359
           HP KHEVRF   R+VHDF+Y  L   L       Q+ AP +             V  P  
Sbjct: 312 HPTKHEVRFRDGRMVHDFLYGTLHRTLGDVRPDDQLAAPIVT-----------AVVRPSG 360

Query: 360 PMIDTTQQERVWQAVQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPWVASPKTASTGKE 419
           P       +       N    P+  P     +       + +    P  A P        
Sbjct: 361 PQAGEFGPQGEMSLAANLLQSPQSQPSYTAPNAGAGSGYQYQYTPRPQSAVP-------- 412

Query: 420 RYGSASVSKKEAAVYQTLMQTPDLSDEEPSTASTIVSSIEAVKANIAIEKLGKAIQVVAG 479
                 V++ +AA  +     P      P         +   +    I  LG A+  + G
Sbjct: 413 ------VAEAQAAYREFFAPLPGAEPGAP---------VALPEGGGDIPPLGYALAQLKG 457

Query: 480 QYLLMSSPQGCVLISLYQAQQLKLRGLLN---AQHGALKAQPLLVPLALKLNESEWQVAQ 536
            Y+L  +  G VL+ ++ A +  +   L    A  G L  QPLLVP +L +++ E   A+
Sbjct: 458 IYILAENAHGLVLVDMHAAHERIMYERLKIAMASEG-LSGQPLLVPESLAVSQREADCAE 516

Query: 537 RHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQL----LPDLLSYAASCSESQALS 592
            H S   +LG EL+     ++ +  +P  L+Q    +L    L DL+ Y  S    QA  
Sbjct: 517 EHHSVFQKLGFELQRLGPETLAIRQIPALLKQAEANRLVADVLADLMEYGTS-DRIQAHI 575

Query: 593 HQALADWLTQRIVVEKRDYTLAEAIGLIAELE 624
           ++ L        +   R   L E  GL+ ++E
Sbjct: 576 NELLGTMACHGAIRANRRLALPEMNGLLRDME 607