Pairwise Alignments

Query, 653 a.a., DNA mismatch repair protein MutL from Vibrio cholerae E7946 ATCC 55056

Subject, 615 a.a., DNA mismatch repair protein MutL from Escherichia coli HS(pFamp)R (ATCC 700891)

 Score =  567 bits (1460), Expect = e-166
 Identities = 326/661 (49%), Positives = 421/661 (63%), Gaps = 59/661 (8%)

Query: 1   MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNG 60
           M I++LP +LANQIAAGEVVERPASVVKELVENSLDAGATRIDID+E+GGAKLIRIRDNG
Sbjct: 1   MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNG 60

Query: 61  SGIDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEA 120
            GI KDEL LAL+RHATSKI +LDDLEAI+SLGFRGEALASISSVSRLTLTSRT  Q+EA
Sbjct: 61  CGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQQEA 120

Query: 121 WSAYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIAL 180
           W AY+EGRDM V ++PAAHPVGTT+EVLDLF+NTPARRKFLRTEKTEF HIDE+++RIAL
Sbjct: 121 WQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFNHIDEIIRRIAL 180

Query: 181 SRFDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWI 240
           +RFDV+  L HNGKIVRQYRA     Q+E+RL A+CG  F++  L IE +H  L L GW+
Sbjct: 181 ARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGTAFLEQALAIEWQHGDLTLRGWV 240

Query: 241 TTPEGARQQ-SDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVD 299
             P       +++QYCYVNGRMMRD+LINHAIRQ+ E  L  DQ   +VL++E+DPHQVD
Sbjct: 241 ADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVD 300

Query: 300 VNVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEEVNPPVV 359
           VNVHPAKHEVRFHQ+RLVHDFIYQ + S L Q  Q+  P                    +
Sbjct: 301 VNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQ--QLETP--------------------L 338

Query: 360 PMIDTTQQERVWQAVQNTPDYPRKAPRDN---DRDESDNPQVRERAVSNPWVASPKTAST 416
           P+ D  Q              PR  P +     R+    P  RE  V+  +  +P + S 
Sbjct: 339 PLDDEPQPA------------PRSIPENRVAAGRNHFAEPAARE-PVAPRYTPAPASGSR 385

Query: 417 GKERYGSA--SVSKKEAAVYQTLMQTPDLSDE----EPSTASTIVSSIEAVKANIAIEKL 470
               + +A     K++  VY+ L+QTP    +    EP   +   +S          +  
Sbjct: 386 PAAPWPNAQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANS----------QSF 435

Query: 471 GKAIQVVAGQYLLMSSPQGCVLISLYQAQQLKLRGLLNAQHGALKAQPLLVPLALKLNES 530
           G+ + +V     L+       L+SL  A++   +  L      + AQPLL+PL LK++  
Sbjct: 436 GRVLTIVHSDCALLERDGNISLLSLPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSAE 495

Query: 531 EWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAASCSESQA 590
           E    ++  SAL +LGI+ +S   H + + AVP PLRQQNLQ L+P+L+ Y A   +   
Sbjct: 496 EKSALEKAQSALAELGIDFQSDAQH-VTIRAVPLPLRQQNLQILIPELIGYLA---KQSV 551

Query: 591 LSHQALADWLTQRIVVEKRDYTLAEAIGLIAELEQLWQGNLPLQDPHFITLVDFSASITA 650
                +A W+ + ++ E   +++A+AI L+A++E+L    +       +  VD   +I A
Sbjct: 552 FEPGNIAQWIARNLMSEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKA 611

Query: 651 L 651
           L
Sbjct: 612 L 612