Pairwise Alignments

Query, 653 a.a., DNA mismatch repair protein MutL from Vibrio cholerae E7946 ATCC 55056

Subject, 642 a.a., DNA mismatch repair endonuclease MutL from Dickeya dianthicola ME23

 Score =  588 bits (1515), Expect = e-172
 Identities = 336/671 (50%), Positives = 437/671 (65%), Gaps = 52/671 (7%)

Query: 1   MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNG 60
           M I++LP +LANQIAAGEVVERPASVVKELVENSLDAGATRIDI++E+GGAKLIRIRDNG
Sbjct: 1   MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIEIERGGAKLIRIRDNG 60

Query: 61  SGIDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEA 120
            GI K EL LAL+RHATSKI TLDDLEAI+SLGFRGEALASISSVSRL LTSRT AQ EA
Sbjct: 61  CGIGKAELALALARHATSKIATLDDLEAIVSLGFRGEALASISSVSRLILTSRTDAQVEA 120

Query: 121 WSAYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIAL 180
           W AY+EGR+MAV ++PAAHPVGTT+EVLDLF+NTPARRKFLRTEKTEF HIDE+++RIAL
Sbjct: 121 WQAYAEGREMAVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFMHIDEVVRRIAL 180

Query: 181 SRFDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWI 240
           +RFDV+ TL HNGK+ RQYRA +   Q+E+RL ++CG  F+QH L +  +H  LK+HGW+
Sbjct: 181 ARFDVAITLHHNGKLTRQYRAVSEPAQRERRLGSICGAAFLQHALAVSWQHGDLKIHGWV 240

Query: 241 TTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVDV 300
             P G+RQ  ++QYCYVN RMMRD+LINHAIRQ+Y+  LR +Q   YVL++E+DPHQVDV
Sbjct: 241 ADPTGSRQLPEMQYCYVNQRMMRDRLINHAIRQAYQDQLRDEQQPAYVLYLEVDPHQVDV 300

Query: 301 NVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEEVNPPVVP 360
           NVHPAKHEVRFHQARLVHDFIYQA+ + L Q A                       P + 
Sbjct: 301 NVHPAKHEVRFHQARLVHDFIYQAVMTVLQQAAS----------------------PGLT 338

Query: 361 MIDTTQQERVWQAVQNTPDYPRKAPRDND--RDESDNPQVRERAVSNPWVASP-KTASTG 417
            +  T+    WQ         R A  +N   R     P+    A S    + P + A   
Sbjct: 339 GVGDTETAATWQPEN------RAAAGENQFARPAEPAPETASAASSGSTASHPGRHARER 392

Query: 418 KERY-GSASVSKKEAAVYQTLMQTPD-----LSDEEPSTASTIVSSIEAVKANIAIEK-- 469
           +  Y  +A   KK+  +YQ L+ T       ++ E P   +T  +  +  +  +A+    
Sbjct: 393 QPAYTEAAGYQKKQGELYQQLLHTESSRQQTVAREAPPVKNTPAARHDVTEKAVAVGDAP 452

Query: 470 -------LGKAIQVVAGQYLLMSSPQGCVLISLYQAQQ-LKLRGLLNAQHG-ALKAQPLL 520
                  LG+ + V    Y L+   QG  ++SL  A++ L+   L   + G  L+ QPLL
Sbjct: 453 LESHALGLGRVLTVYPPSYALVEYQQGLAVLSLTVAERYLRQAQLTPLEAGEGLRPQPLL 512

Query: 521 VPLALKLNESEWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLS 580
           +P  L LN SE  V Q+    L +LGIE++     + +  AVP PLRQQNLQ L+ DLL 
Sbjct: 513 IPQRLTLNPSELAVMQQQQPLLTRLGIEVELAPPRATL-RAVPLPLRQQNLQNLISDLLG 571

Query: 581 YAASCSESQALSHQALADWLTQRIVVEKRDYTLAEAIGLIAELEQLWQGNLPLQDPHFIT 640
           Y A   +S  +   A+A W+  R+  E+ ++TLA+A+ L++++E+L    +       + 
Sbjct: 572 YLA---DSHDVKPDAVAAWIAGRLGSERENWTLAQAVQLLSDVERLCPLQVKAPPSELLY 628

Query: 641 LVDFSASITAL 651
           ++D  ++I AL
Sbjct: 629 VMDIESAIRAL 639