Pairwise Alignments

Query, 649 a.a., acetyl-coenzyme A synthetase from Vibrio cholerae E7946 ATCC 55056

Subject, 658 a.a., Acetyl-CoA synthetase (EC 6.2.1.1) from Variovorax sp. SCN45

 Score =  627 bits (1617), Expect = 0.0
 Identities = 328/635 (51%), Positives = 426/635 (67%), Gaps = 18/635 (2%)

Query: 19  ADNDTYLAMYQQSIKDPEGFWSEHGK-IVDWIKPFTKVKHTSFDPGHIDIRWFEDGTLNV 77
           A    Y A+  ++  D EG+W+   +  V W  PF +   +S  P +   RWFEDGTLNV
Sbjct: 26  AGRAAYDALVAEAEADHEGYWARLAREFVGWKTPFIRTLDSSDAPHY---RWFEDGTLNV 82

Query: 78  SANCIDRHLAT-RGDQVAIIWEGDDPTQDKTLTYKQLHQEVCRFANALKEQGVRKGDVVC 136
           S NC+DR +A  RGD+VAI++E DD    +T TY QL  + CR ANALK  GVRKGD V 
Sbjct: 83  SWNCLDRQVAAGRGDKVAIVFESDDGQVTRT-TYAQLLAQTCRMANALKSLGVRKGDRVV 141

Query: 137 IYMPMVPEAAVAMLACTRIGAVHTIVFGGFSPEALAGRIIDSNAKLVITADEGVRGGRAV 196
           IYMPM  E  VAM AC R+GAVH++VFGGFS  AL  R+ D+ A +++TA + VRGG+ +
Sbjct: 142 IYMPMSVEGVVAMQACARLGAVHSVVFGGFSAHALRDRVADTGATVIVTAAQQVRGGKRL 201

Query: 197 PLKKNVDEALCNPEVKNISKVMVLKRTGGNVAWHEHRDIWWHEATAKASDNCPPEEMKAE 256
           PLK  VDEAL     + +  V+V +RTG  + W   RD+W HE T    D+C PE + AE
Sbjct: 202 PLKALVDEALALGGCEAVRSVVVHRRTGEPIEWTA-RDVWMHEITQAQGDSCEPEWVGAE 260

Query: 257 DPLFILYTSGSTGKPKGVLHTTGGYLVYATMTFKYVFDYQPNEVFWCTADVGWITGHSYL 316
            PLF+LYTSGSTGKPKGV H +GGYL++A +T K+ FD   ++VFWCTAD+GW+TGH+Y+
Sbjct: 261 HPLFLLYTSGSTGKPKGVQHCSGGYLLHAALTTKWTFDMHDDDVFWCTADIGWVTGHTYI 320

Query: 317 VYGPLANGAKTILFEGVPNYPTTARMSEVVDKHKVNILYTAPTAIRALM--AKGDEAIKG 374
            YGPLA GA  ++FEGVP YP   R  +++++H+V + YTAPTAIR+L+  A+G+ A+  
Sbjct: 321 AYGPLAIGATQVVFEGVPTYPDAGRFWQMIERHRVTVFYTAPTAIRSLIKAAEGNPAVHP 380

Query: 375 TSRD--SLRIMGSVGEPINPEAWEWYYRTIGNEKSPIVDTWWQTETGGILITPLPGATAL 432
              D  SLR++GSVGEPINP AWEWY + +G  + P++DTWWQTETGG +ITPLPGAT L
Sbjct: 381 DRHDLGSLRVLGSVGEPINPAAWEWYRQHVGGGRCPVLDTWWQTETGGHMITPLPGATDL 440

Query: 433 KPGSATRPFFGVQPALVDNMGEIVEGATEGNLVLLDSWPGQMRTVYGDHDRFEQTYF-ST 491
            PGS T PF G+  A+VD  G  V     G LV+   WP  +R V+GD  R+  +YF   
Sbjct: 441 VPGSCTLPFPGIAAAIVDETGNDVPDGESGLLVIKKPWPSMIRAVWGDDARYRSSYFPPE 500

Query: 492 FKGMYFTGDGARRDE-DGYYWITGRVDDVLNVSGHRMGTAEIESALVAFNK-IAEAAVVG 549
            +G Y  GDGA RD    Y+ I GR+DDVLNVSGHRMGT EIESALVA    +AEAAVVG
Sbjct: 501 LRGCYLAGDGAARDRLTRYFTIGGRIDDVLNVSGHRMGTMEIESALVACAALVAEAAVVG 560

Query: 550 VPHDIKGQAIYAYITLNDGVYPSAE---LHKEVKDWVRKEIGAIATPDVLHWTDALPKTR 606
            P +  G+AI A++ L        E   L  E++ W+ KEIG IA P  + + D LPKTR
Sbjct: 561 RPDETTGEAISAFVVLKQPRPTGKEGDRLAAELRAWIGKEIGPIAKPREIRFADNLPKTR 620

Query: 607 SGKIMRRILRKIATGDTSNLGDTSTLADPSVVDRL 641
           SGKIMRR+LR +A G+  +  D STL +P+++D+L
Sbjct: 621 SGKIMRRLLRSVARGEAIS-QDVSTLENPAILDQL 654