Pairwise Alignments

Query, 649 a.a., acetyl-coenzyme A synthetase from Vibrio cholerae E7946 ATCC 55056

Subject, 1285 a.a., acetate--CoA ligase from Pontibacter actiniarum KMM 6156, DSM 19842

 Score =  708 bits (1828), Expect = 0.0
 Identities = 344/622 (55%), Positives = 443/622 (71%), Gaps = 6/622 (0%)

Query: 22   DTYLAMYQQSIKDPEGFWSEHGKIVDWIKPFTKVKHTSFDPGHIDIRWFEDGTLNVSANC 81
            D Y   Y++S +DPEGFW++      W K + KV   +F+     ++WF+ G +N++ NC
Sbjct: 663  DEYQDAYKRSTEDPEGFWADVADTFTWRKKWDKVLEWNFEEP--SVKWFQGGKMNITENC 720

Query: 82   IDRHLATRGDQVAIIWEGDDPTQDKT-LTYKQLHQEVCRFANALKEQGVRKGDVVCIYMP 140
            +DRHL TRG+++A+IWE +DP +    LTY++LH++VC+FAN LK+ G +KGD +CIYMP
Sbjct: 721  LDRHLKTRGNKLALIWEPNDPKERFVRLTYRELHEKVCQFANVLKKNGAKKGDRICIYMP 780

Query: 141  MVPEAAVAMLACTRIGAVHTIVFGGFSPEALAGRIIDSNAKLVITADEGVRGGRAVPLKK 200
            MVPE A+A+LAC RIGA+H++VF GFS  A+A RI D+   +V+T+D   RG + +P+K+
Sbjct: 781  MVPELAIAVLACARIGAIHSVVFAGFSASAMADRINDAQCSMVLTSDGLNRGAKQIPVKR 840

Query: 201  NVDEALCNPEVKNISKVMVLKRTGGNVAWHEHRDIWWHEATAKASDNCPPEEMKAEDPLF 260
             VDEAL   +  ++ KV+V++R G  V   E RD+W+H+       +CP EEM AED LF
Sbjct: 841  VVDEAL--EDCTSVKKVIVVERLGWAVNMVEGRDVWYHDEVQTVGKDCPAEEMDAEDMLF 898

Query: 261  ILYTSGSTGKPKGVLHTTGGYLVYATMTFKYVFDYQPNEVFWCTADVGWITGHSYLVYGP 320
            ILYTSGSTGKPKGV+HT GGY+VYA  +F  VF YQ ++V+WCTAD+GWITGH+YLVYGP
Sbjct: 899  ILYTSGSTGKPKGVVHTCGGYMVYAQYSFCNVFQYQESDVYWCTADIGWITGHTYLVYGP 958

Query: 321  LANGAKTILFEGVPNYPTTARMSEVVDKHKVNILYTAPTAIRALMAKGDEAIKGTSRDSL 380
            L  GA T++FEGVP YP   R  +VVDK  V I YTAPTAIRALM    + +   S DSL
Sbjct: 959  LLAGATTLMFEGVPTYPDMGRFWQVVDKFGVTIFYTAPTAIRALMGGDLDNVLSYSLDSL 1018

Query: 381  RIMGSVGEPINPEAWEWYYRTIGNEKSPIVDTWWQTETGGILITPLPGATALKPGSATRP 440
            R++GSVGEPIN EAW WY+  +G E  P+VDTWWQTETGGI+I+ L   T +KP  A  P
Sbjct: 1019 RVLGSVGEPINEEAWHWYHIHVGKEDCPVVDTWWQTETGGIMISTLADVTPMKPSHAGLP 1078

Query: 441  FFGVQPALVDNMG-EIVEGATEGNLVLLDSWPGQMRTVYGDHDRFEQTYFSTFKGMYFTG 499
              G+QP LVD+ G EI E   EG L +   WP  +RT YGDH+R   +YFST+KG+YFTG
Sbjct: 1079 LPGIQPILVDSDGNEITENGVEGYLCVKFPWPSMIRTTYGDHERARLSYFSTYKGLYFTG 1138

Query: 500  DGARRDEDGYYWITGRVDDVLNVSGHRMGTAEIESALVAFNKIAEAAVVGVPHDIKGQAI 559
            DGA+RDE+G Y I GRVDDV+NVSGHR GTAEIE A+     + E+AVVG PHD+KGQ I
Sbjct: 1139 DGAKRDENGLYRIIGRVDDVINVSGHRFGTAEIEEAINHNEHVIESAVVGYPHDVKGQGI 1198

Query: 560  YAYITLNDGVYPSAELHKEVKDWVRKEIGAIATPDVLHWTDALPKTRSGKIMRRILRKIA 619
            YA++ L D       L  E+ + V ++IG IA PD +     LPKTRSGKIMRRILRK+A
Sbjct: 1199 YAFVILKDKPERDDWLRAEIIETVVEKIGKIAKPDKIQIVSGLPKTRSGKIMRRILRKVA 1258

Query: 620  TGDTSNLGDTSTLADPSVVDRL 641
             GDTSNLGDTSTL DP VV+ +
Sbjct: 1259 EGDTSNLGDTSTLLDPEVVEEI 1280



 Score =  438 bits (1127), Expect = e-127
 Identities = 248/629 (39%), Positives = 364/629 (57%), Gaps = 20/629 (3%)

Query: 22  DTYLAMYQQSIKDPEGFWSEHGKIVDWIKPFTKVKHTSFDPGHIDIRWFEDGTLNVSANC 81
           + Y   Y QSI DPE FW E  + + W +   +V  T  +  +   RW++ G LN +   
Sbjct: 9   NNYAEAYAQSIADPEAFWGEQAEQLAWYEKPQQVLTTDENGFY---RWYKGGKLNTAYLA 65

Query: 82  IDRHLAT-RGDQVAIIWEGDDPTQDKTLTYKQLHQEVCRFANALKEQGVRKGDVVCIYMP 140
           +D H+   RGDQ A+I++       K  TY +L   V RFA AL++ GV KGD V IYMP
Sbjct: 66  LDYHVENGRGDQTALIYDSPVTGTIKKYTYAELRDFVARFAGALQQLGVGKGDTVVIYMP 125

Query: 141 MVPEAAVAMLACTRIGAVHTIVFGGFSPEALAGRIIDSNAKLVITADEGVRGGRAVPLKK 200
           ++PEA VAMLAC R+GAVH++VFGGF+P  L  RI D+  K+VI+A  G+   + +P K 
Sbjct: 126 VIPEAMVAMLACARLGAVHSVVFGGFAPHELCVRIDDAKPKVVISASCGIEFDKVIPYKP 185

Query: 201 NVDEALCNPEVKNISKVMVLKRTGGNVAWHEHRDIWWHEATAKASD-NCPPEEMKAEDPL 259
            +D+AL N         ++ +R     A  + RD+ + E   +A+  +C P  + A DPL
Sbjct: 186 LLDKAL-NDSTHKPEHTIIFQRPQVQAAMQQGRDLDYVEVLEQAAPADCVP--VDATDPL 242

Query: 260 FILYTSGSTGKPKGVLHTTGGYLVYATMTFKYVFDYQPNEVFWCTADVGWITGHSYLVYG 319
           +ILYTSG+TGKPKG++   GG+ V    + K V+D  P +VFW  +DVGW  GHSYLVYG
Sbjct: 243 YILYTSGTTGKPKGIVRDNGGHAVALKYSMKAVYDVDPGDVFWAASDVGWAVGHSYLVYG 302

Query: 320 PLANGAKTILFEGVP-NYPTTARMSEVVDKHKVNILYTAPTAIRALMAKGDEAI--KGTS 376
           PL +G  +ILFEG P   P       ++ +H+V +L+TAPTA RA+  +  + +  K   
Sbjct: 303 PLIHGCTSILFEGKPVRTPDAGTFWRIIQQHEVKVLFTAPTAFRAIKKEDPDGLLKKKYD 362

Query: 377 RDSLRIMGSVGEPINPEAWEWYYRTIGNEKSPIVDTWWQTETGGILITPLPG--ATALKP 434
             SL+ +   GE  +   + W    +   + P++D WWQTE+G  ++  + G      KP
Sbjct: 363 TPSLKYLFLAGERCDVSTYYWAKNLL---QVPVIDHWWQTESGWPMVANMAGLELQPAKP 419

Query: 435 GSATRPFFGVQPALVDNMGEIVEGATEGNL-VLLDSWPGQMRTVYGDHDRFEQTYFSTFK 493
           GSA +P  G +  +++  G+ +    EG + V L   PG + T++ D +RF ++Y   F 
Sbjct: 420 GSAGKPVCGYEVHILNEEGQQLIPNQEGVVAVKLPLPPGCLPTLWEDDERFRKSYLERFP 479

Query: 494 GMYFTGDGARRDEDGYYWITGRVDDVLNVSGHRMGTAEIESALVAFNKIAEAAVVGVPHD 553
           G Y TGDG   DE+GY +I GR+DDV+NVSGHR+ T E+E  + +   +AE AV+G+  D
Sbjct: 480 GYYMTGDGGYIDEEGYVYIMGRIDDVINVSGHRLSTGEMEEMVSSHPAVAECAVIGIADD 539

Query: 554 IKGQAIYAYITLNDG-VYPSAELHKEVKDWVRKEIGAIATPDVLHWTDALPKTRSGKIMR 612
           ++GQ     + L DG      EL +E+   +R +IGA+A    +     LPKTRSGKI+R
Sbjct: 540 LRGQRPVGLVVLKDGQTIGEQELEQELVALLRDKIGAVAYFKTVVLVQRLPKTRSGKILR 599

Query: 613 RILRKIATGDTSNLGDTSTLADPSVVDRL 641
           RILR IA G  +     ST+ DP+++  +
Sbjct: 600 RILRHIADG--TPYAVPSTIDDPAILTEI 626