Pairwise Alignments

Query, 598 a.a., phosphogluconate dehydratase from Vibrio cholerae E7946 ATCC 55056

Subject, 616 a.a., dihydroxy-acid dehydratase from Enterobacter asburiae PDN3

 Score =  175 bits (444), Expect = 4e-48
 Identities = 171/593 (28%), Positives = 258/593 (43%), Gaps = 77/593 (12%)

Query: 63  DFTRSNVAIVTSYNDMLSAHQPYQHYPDRIKMVLAEYGHTAQVAGGVP------AMCDGV 116
           DF +  +A+V S+   +  H    H  D  K+V  +     + +GGV       A+ DG+
Sbjct: 31  DFGKPIIAVVNSFTQFVPGHV---HLRDLGKLVAEQI----EASGGVAKEFNTIAVDDGI 83

Query: 117 TQGQPGMDMSLFSRDLIAQATALSLSHNVFDATLLLGICDKIAPGQLMGALSYAHLPTAF 176
             G  GM  SL SR+LIA +    ++ +  DA + +  CDKI PG LM +L   ++P  F
Sbjct: 84  AMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLR-LNIPVIF 142

Query: 177 MPAGLMATG-------ISNEEKVDIRQKYAAGEVGKDALLNMECQAYHAPGTCTFYGTAN 229
           +  G M  G       I   + VD   + A  +V  +    +E  A    G+C+   TAN
Sbjct: 143 VSGGPMEAGKTKLSDKIIKLDLVDAMIQGADPKVSDEQSDQVERSACPTCGSCSGMFTAN 202

Query: 230 TNQLVFEAMGLMLPGSAFVHPHSALRQALNDDATVKIASMT-----QGSAQYRPLYQVVT 284
           +   + EA+GL  PG+  +    A R+ L  +A  +I  +T     Q  A   P   + +
Sbjct: 203 SMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQDDASALP-RNIAS 261

Query: 285 EKSLLNGIVALLASGGSTNHTIHMLAVARAAGILLTWQDISDLSDVVPLLAKVYPNGPA- 343
           + +  N +   +A GGSTN  +H+LA A+ A I  T  DI  LS  VP L KV P+    
Sbjct: 262 KAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKY 321

Query: 344 DMNAFQQAGGVPALMKRLHESKLLHSDVTPVFGEFRDQLTLPELVD-------------- 389
            M    +AGGV  ++  L  + LL+ +V  V G     LTLPE +D              
Sbjct: 322 HMEDVHRAGGVLGILGELDRAGLLNREVKNVLG-----LTLPESLDQYDVMLTKDDAVKK 376

Query: 390 ----------------GELCWKACEGTRDAQVIAASGECFQTTGGTKMLNGNLGR--AVI 431
                            +  W   +  R    I +    +   GG  +L GN      ++
Sbjct: 377 MFRAGPAGIRTTQAFSQDCRWDTLDDDRAEGCIRSLEYAYSKDGGLAVLYGNFAENGCIV 436

Query: 432 KVSAVKEEQRIIEAPAVVFQCQHQVEAAYQRGELNKDCIVVVTHNGPAAN-GMPELHKLM 490
           K + V +       PA V++ Q     A   G++    +VV+ + GP    GM E+    
Sbjct: 437 KTAGVDDSILKFTGPAKVYESQDDAVDAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPT 496

Query: 491 PILGNVQKAGFKVALVTDGRLSGASGKIPSAIHVSPEAVRGGAIGLVRDGDLLRLDC-TT 549
             L ++   G   AL+TDGR SG +  + S  HVSPEA  GG I ++ DGDL+ +D    
Sbjct: 497 TFLKSM-GLGKACALITDGRFSGGTSGL-SIGHVSPEAASGGNIAIIEDGDLIEIDIPNR 554

Query: 550 GTLENLTDMSHRQALALDTERDQQMW-----GRELFKVMRQAVS---SAEQGA 594
           G    L+D            R  + W      RE+   +R   S   SA++GA
Sbjct: 555 GIQLKLSDQEIAARREAQEARGDKAWTPKDRQREVSFALRAYASLATSADKGA 607