Pairwise Alignments

Query, 598 a.a., phosphogluconate dehydratase from Vibrio cholerae E7946 ATCC 55056

Subject, 616 a.a., dihydroxy-acid dehydratase from Escherichia coli ECRC62

 Score =  177 bits (449), Expect = 1e-48
 Identities = 159/536 (29%), Positives = 240/536 (44%), Gaps = 68/536 (12%)

Query: 63  DFTRSNVAIVTSYNDMLSAHQPYQHYPDRIKMVLAEYGHTAQVAGGVP------AMCDGV 116
           DF +  +A+V S+   +  H    H  D  K+V  +     + AGGV       A+ DG+
Sbjct: 31  DFGKPIIAVVNSFTQFVPGHV---HLRDLGKLVAEQI----EAAGGVAKEFNTIAVDDGI 83

Query: 117 TQGQPGMDMSLFSRDLIAQATALSLSHNVFDATLLLGICDKIAPGQLMGALSYAHLPTAF 176
             G  GM  SL SR+LIA +    ++ +  DA + +  CDKI PG LM +L   ++P  F
Sbjct: 84  AMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLR-LNIPVIF 142

Query: 177 MPAGLMATG-------ISNEEKVDIRQKYAAGEVGKDALLNMECQAYHAPGTCTFYGTAN 229
           +  G M  G       I   + VD   + A  +V       +E  A    G+C+   TAN
Sbjct: 143 VSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTAN 202

Query: 230 TNQLVFEAMGLMLPGSAFVHPHSALRQALNDDATVKIASMT-----QGSAQYRPLYQVVT 284
           +   + EA+GL  PG+  +    A R+ L  +A  +I  +T     Q      P   + +
Sbjct: 203 SMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALP-RNIAS 261

Query: 285 EKSLLNGIVALLASGGSTNHTIHMLAVARAAGILLTWQDISDLSDVVPLLAKVYPNGPA- 343
           + +  N +   +A GGSTN  +H+LA A+ A I  T  DI  LS  VP L KV P+    
Sbjct: 262 KAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKY 321

Query: 344 DMNAFQQAGGVPALMKRLHESKLLHSDVTPVFGEFRDQLTLPELVD-------------- 389
            M    +AGGV  ++  L  + LL+ DV  V G     LTLP+ ++              
Sbjct: 322 HMEDVHRAGGVIGILGELDRAGLLNRDVKNVLG-----LTLPQTLEQYDVMLTQDDAVKN 376

Query: 390 ----------------GELCWKACEGTRDAQVIAASGECFQTTGGTKMLNGNLGR--AVI 431
                            +  W + +  R    I +    +   GG  +L GN      ++
Sbjct: 377 MFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIV 436

Query: 432 KVSAVKEEQRIIEAPAVVFQCQHQVEAAYQRGELNKDCIVVVTHNGPAAN-GMPELHKLM 490
           K + V +       PA V++ Q     A   G++    +VV+ + GP    GM E+    
Sbjct: 437 KTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPT 496

Query: 491 PILGNVQKAGFKVALVTDGRLSGASGKIPSAIHVSPEAVRGGAIGLVRDGDLLRLD 546
             L ++   G   AL+TDGR SG +  + S  HVSPEA  GG+IGL+ DGDL+ +D
Sbjct: 497 SFLKSM-GLGKACALITDGRFSGGTSGL-SIGHVSPEAASGGSIGLIEDGDLIAID 550