Pairwise Alignments

Query, 530 a.a., bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase from Vibrio cholerae E7946 ATCC 55056

Subject, 530 a.a., IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) from Sphingobium sp. HT1-2

 Score =  526 bits (1355), Expect = e-154
 Identities = 297/536 (55%), Positives = 356/536 (66%), Gaps = 24/536 (4%)

Query: 7   IHRALLSVSDKTGIVEFAKALAERGVELLSTGGTARLLAEQGLTVTEVSDYTGFPEMMDG 66
           I RALLSVSDKTG++E  +AL + GVEL+STGGTA+ L E GL V ++S+ TGFPEMMDG
Sbjct: 7   IKRALLSVSDKTGLIELGQALGQHGVELVSTGGTAKALREAGLAVKDISELTGFPEMMDG 66

Query: 67  RVKTLHPKVHGGILGRRGQDD--AVMNTHGIQPIDMVVVNLYPFAQTVANPNCTLADAVE 124
           RVKTLHPKVHGG+L  RG  +  A M+ H I  ID+V+VNLYPFA TVA       + +E
Sbjct: 67  RVKTLHPKVHGGLLAVRGNPEHVASMDEHAIGAIDLVIVNLYPFAATVAK-GADRDEIIE 125

Query: 125 NIDIGGPTMVRSAAKNHKDVAIVVNAHDYDRVIREMDANHNSLTLATRFDLAIAAFEHTA 184
           NIDIGGP+MVRSAAKNH+ VAIV +  DY R+I EM     + +   R  LA  A+  TA
Sbjct: 126 NIDIGGPSMVRSAAKNHESVAIVTDPADYARLIAEMAEKGGATSYDFRRMLAAKAYAATA 185

Query: 185 AYDGMIANYFGTLVPSYGDNKEGDEESKFPRTFNAQFIKKQDMRYGENSHQAAAFYVEAN 244
           AYD MIA++F             D+   FP + +        +RYGEN HQ+AA Y+   
Sbjct: 186 AYDSMIASWFAF----------ADQGVAFPESLSLSSKLSTTLRYGENPHQSAALYLPNG 235

Query: 245 PQEASVATARQIQGKALSYNNIADTDAALECVKEFSE--PACVIVKHANPCGVALGDDLL 302
           P    +A A+QIQGK LSYNN  D DAALE V EF +  P  VIVKHANPCGVA G+ L+
Sbjct: 236 PTANGIAQAKQIQGKELSYNNYNDADAALELVSEFRDGPPTVVIVKHANPCGVATGETLI 295

Query: 303 QAYNRAYQTDPTSAFGGIIAFNRELDGETARAIIERQFVEVIIAPKVSQAAIDIVAAKQN 362
           +AY  A   D  SAFGGIIA NR LDG TA A I   F EV+ AP     A  I A K+N
Sbjct: 296 EAYEAALACDSVSAFGGIIAVNRPLDGPTAEA-ISGIFTEVVAAPDADDEAKAIFAKKKN 354

Query: 363 VRLLECGEWQGQT-TGFDLKRVNGGLLVQDRDQGMVAQDDLQVVSTRQPSDAELKDALFC 421
           +RLL  GE       G  +K + GGLLVQ RD G V  D L+VV+ R P++ ELKD LF 
Sbjct: 355 LRLLLTGELPDPARPGLMVKSIAGGLLVQSRDNGKVDLDALKVVTKRAPTEQELKDCLFA 414

Query: 422 WKVAKYVKSNAIVYAKGDMTIGIGAGQMSRVYSAKIAGIKAADEGLEVA-------GSVM 474
           W VAK+VKSNAIVYAKG  T G+GAGQM+R+ SA+IA  KA D   +         GS +
Sbjct: 415 WTVAKHVKSNAIVYAKGGSTAGVGAGQMNRLESARIAAWKAKDAAEKAGWSEPRTIGSAV 474

Query: 475 ASDAFFPFRDGIDAAAEAGITCVIQPGGSMRDQEVIDAANEHGMAMIFTGMRHFRH 530
           ASDAFFPF DG+ AA EAG T VIQPGGS+RD+EVI AA+E G+AM+FTGMRHFRH
Sbjct: 475 ASDAFFPFADGLLAAVEAGATAVIQPGGSIRDEEVIAAADEAGLAMVFTGMRHFRH 530