Pairwise Alignments

Query, 611 a.a., vitamin B12 transporter BtuB from Vibrio cholerae E7946 ATCC 55056

Subject, 614 a.a., vitamin B12/cobalamin outer membrane transporter (NCBI) from Escherichia coli BW25113

 Score =  395 bits (1014), Expect = e-114
 Identities = 242/621 (38%), Positives = 346/621 (55%), Gaps = 25/621 (4%)

Query: 8   IALASLLTPISYLH----ANEAQPQETVVVTANRFEQKASSTLADVEIITRQDIEQTQAK 63
           I  ASLLT  S       A +  P +T+VVTANRFEQ  S+ LA   ++TRQDI++ Q+ 
Sbjct: 2   IKKASLLTACSVTAFSAWAQDTSP-DTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQST 60

Query: 64  TLPELLRRLTGVQITQNGGRGQLASLFVRGTSSDQVLVLVDGIRFARA-AKGAVDFNQIP 122
           ++ ++LRRL GV ITQNGG GQL+S+F+RGT++  VLVL+DG+R   A   G+ D +Q P
Sbjct: 61  SVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFP 120

Query: 123 LTYVDRIEYVRGARASLYGSEAIGGVINIITKARSQQQGTTVSAGLGSLDYQELSIASGV 182
           +  V R+EY+RG R+++YGS+AIGGV+NIIT     + GT +SAG GS  YQ   +++  
Sbjct: 121 IALVQRVEYIRGPRSAVYGSDAIGGVVNIIT--TRDEPGTEISAGWGSNSYQNYDVSTQQ 178

Query: 183 AIGEKGQMNVALGTESDKGYNVRPVPGVNDG-----DRHGFRSDNALLGYVHQFDESWSL 237
            +G+K ++ +        GY+V  V   N G     D  GF S        H F ++WS 
Sbjct: 179 QLGDKTRVTLLGDYAHTHGYDV--VAYGNTGTQAQTDNDGFLSKTLYGALEHNFTDAWSG 236

Query: 238 FANARAYENIYQYDNSY--GTRDYKEAEKDDLSFTIGTQYQSERWVSELQLTTQKQKSWD 295
           F     Y+N   YD  Y  G+      +    S+  G +Y  E   S+L  +    K ++
Sbjct: 237 FVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYN 296

Query: 296 YTQSKGKY--SDTSDNLEQRNIQWINRYLVNDVWTFAGGVDWRDESYIDKTADKE--FDR 351
           Y    G+Y  S T D ++Q  +QW N  +V    +   GVDW+ ++    T   E  +D+
Sbjct: 297 YDPHYGRYDSSATLDEMKQYTVQWANNVIVGH-GSIGAGVDWQKQTTTPGTGYVEDGYDQ 355

Query: 352 SNTAAFAVVAAEWQQWLLEASLRFDDNQEYGSQTTHNIALGYQFIPEFGVKASYGSAFKA 411
            NT  +     +   +  E + R DDN ++G   T   + G++FI  +   ASYG+++KA
Sbjct: 356 RNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKA 415

Query: 412 PNLYQQYDPSYGNVNLQPEDADSAELSFYGLFSGIKWSITGYDYKINNLIDYNSTTKNYQ 471
           PNL Q Y   YGN NL PE +   E +F GL +G+ W I+GY   +++LIDY+  T  Y 
Sbjct: 416 PNLGQLYG-FYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHTLKYY 474

Query: 472 NVIGESNIKGVEFTAEFATGIVQHQLSVDLKDADDSKGKT-LQRRAEHMYKWNALVAFEQ 530
           N  G++ IKGVE TA F TG + H +S D  DA ++   T L RRA+   K+        
Sbjct: 475 NE-GKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYD 533

Query: 531 VDWSIGYQYVGKRPDLDYNTYPTQNITLDAYSLVDTSVSYYVTDSTTISARIDNLLDKEY 590
            DW I YQY+G R D DY++YP Q + +   SL D +V+Y VT   T+  +I NL DK+Y
Sbjct: 534 FDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDY 593

Query: 591 ETANGYPAAERAYYLNIGYQF 611
           ET  GY  A R Y L+  Y F
Sbjct: 594 ETVYGYQTAGREYTLSGSYTF 614