Pairwise Alignments

Query, 934 a.a., DNA polymerase I from Vibrio cholerae E7946 ATCC 55056

Subject, 925 a.a., DNA polymerase I from Pseudomonas simiae WCS417

 Score = 1045 bits (2702), Expect = 0.0
 Identities = 538/937 (57%), Positives = 686/937 (73%), Gaps = 26/937 (2%)

Query: 8   PLILIDGSSYLYRAFHAYPGTMSNGEIPTNAIYGVVNMIRSMMRQFASDRMAVIFDAKGK 67
           PL+L+DGSSYLYRAFHA P   ++  +PT A+ GV+NM++S+ +Q+ +   AV+FDAKG 
Sbjct: 5   PLVLVDGSSYLYRAFHALPPLTTSKGLPTGAVKGVLNMLKSLRKQYPNSPFAVVFDAKGG 64

Query: 68  TFRDEMYDQYKAHRPPMPDELRCQVEPLHQVIRAMGLPLLAIEGVEADDVIGTLARQASQ 127
           TFRDEMY +YKA+RP MPD++R Q+EPLHQ + A+G PLL +EGVEADDVIGTLAR ++ 
Sbjct: 65  TFRDEMYAEYKANRPSMPDDMRLQIEPLHQSVIALGFPLLCVEGVEADDVIGTLARSSAA 124

Query: 128 AGMPVLISTGDKDMAQLVDDNITLINTMTNVVLDREGVIEKFGIPPELIIDYLALMGDKV 187
           A  PV+ISTGDKDMAQLVD +ITL+NTMT   +D EGV EKFG+ PE IIDYLALMGD  
Sbjct: 125 ADRPVVISTGDKDMAQLVDGHITLVNTMTGSAMDIEGVKEKFGVAPEQIIDYLALMGDSS 184

Query: 188 DNIPGVPGVGEKTATALLQGI-GGLEALYANLDKIAALGFRGSKTMAQKLEENRGNAKLS 246
           DNIPGVPG+G KTA+ LL G+ GG++ LY  LD + +L  RG+KT+  KLEE+R  A LS
Sbjct: 185 DNIPGVPGIGPKTASGLLVGVNGGIKELYEQLDIVPSLPIRGAKTLPAKLEEHREMAFLS 244

Query: 247 YQLATIKCDVELEESPQTLLKQTPDRDALMSLYGKLAFKSWLTELLDGGTGIVTADEQTK 306
           YQLATIKCDV L+     L    PDR+ L+ LY  L FKSW  E+            Q  
Sbjct: 245 YQLATIKCDVPLDVGLDDLHLIEPDREKLLELYTLLEFKSWFDEI------------QRD 292

Query: 307 TSSVTVSTAATHAAAIPESPAAHIDRSQYQTILNEQDFQLWLEKLKQAELFAFDTETDNL 366
              V +  AA    A+ E+ A     + Y TIL++  F +WL+KL +A LFAFDTET  +
Sbjct: 293 AKRVELK-AAPAVEAVVETVAP--TEASYTTILDQATFDIWLKKLNEATLFAFDTETTGI 349

Query: 367 DYMVANLVGMSFAVAEGEAAYLPVAHDYLDAPQQLERDWVIAQLKPLLEDESKAKVGQNL 426
           D   A LVG+SFAV   EAAY+P+ H Y+ APQQL+RD V+  LKPLLED +K KVGQ+ 
Sbjct: 350 DAQQAQLVGVSFAVQPHEAAYIPLTHSYIGAPQQLDRDTVLLALKPLLEDPTKLKVGQHA 409

Query: 427 KYDASVMAR--------YGVELRGIRHDTMLQSYVYNSVGGKHDMDSLALRFLQHSCISF 478
           K+D +++A         +G+ +RGI  DTML+SYV NS   +HDMDSLA ++L +  ++F
Sbjct: 410 KFDMNILANCAIGGDPAHGITVRGIAFDTMLESYVLNSTATRHDMDSLAKKYLDYDTVAF 469

Query: 479 EQVAGKGKNQLTFNQIALEEAAQYAAEDADVTLRLHQRIHPLIEQDAKLEQVYREIEMPL 538
           + +AGKG  QLTF+QIALE+A  YAAEDAD+TLRLHQ +   +     L  V  +IE+PL
Sbjct: 470 QDIAGKGAKQLTFDQIALEQAGPYAAEDADITLRLHQELFAQLSAIPSLASVLTDIEIPL 529

Query: 539 VPVLSRIERTGVMIDDMLLSAQSQEIALRLDQLEQNAYELAGQPFNLSSPKQLQTILFEQ 598
           VPVL+RIER G ++D  LL  QS E+  ++ +LE+ A+E+AG+ FNL SPKQL  IL+E+
Sbjct: 530 VPVLARIERQGALVDKDLLGIQSIELGNKMVELERQAFEIAGEEFNLGSPKQLGAILYEK 589

Query: 599 MKLPVLQKTPSGTPSTNEEVLQELALD-YPLPKVLIEYRGLAKLKSTYTDKLPKMINPST 657
           + LPVL+KT  G  ST EEVL +LA D YPLPKVL++YR ++KLKSTYTD+LP+ INP T
Sbjct: 590 LGLPVLKKTGKGQASTAEEVLAKLAEDDYPLPKVLMQYRSMSKLKSTYTDRLPEQINPRT 649

Query: 658 GRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFVAPHGWKIMAVDYSQIELR 717
           GR+HTSYHQAV ATGRLSS+DPNLQNIPVR  EGRRIRQAFVAP G+K++A DYSQIELR
Sbjct: 650 GRIHTSYHQAVAATGRLSSSDPNLQNIPVRTAEGRRIRQAFVAPKGYKLLAADYSQIELR 709

Query: 718 IMAHLSGDQALLDAFRDGKDIHAATAAEIIGVPIDQVSSEQRRRAKAVNFGLIYGMSAFG 777
           IMAHLS D+ L++AFRD  D+H ATAAE+  V +  V+S+QRR AKA+NFGLIYGM A  
Sbjct: 710 IMAHLSKDEGLMNAFRDNLDVHTATAAEVFKVELGDVTSDQRRSAKAINFGLIYGMGAQK 769

Query: 778 LAKQLGIPRGEAQEYMDKYFERYPGVMQYMEDTRSRAAQLGYVETIFGRRLHLPEITSRN 837
           L K +G+    A+ Y+D YF RYPGV +YME TR++AA  GYVET FGRRL+LP+I S  
Sbjct: 770 LGKDIGVDTKTAKAYIDVYFARYPGVREYMERTRAQAADQGYVETFFGRRLYLPDINSNK 829

Query: 838 AMRRKAAERAAINAPMQGTAADIIKKAMLLVDEWIEREGDGRVKLLMQVHDELVFEVKES 897
              R AAER AINAPMQGTAADIIKKAM+ VD W+   G    K+++QVHDELV EV+E 
Sbjct: 830 PQERAAAERTAINAPMQGTAADIIKKAMVRVDNWLTESGLD-AKVILQVHDELVVEVRED 888

Query: 898 SLSEIESKVQQLMESAAELAVPLVAEAGHGDNWEQAH 934
            ++++  K+++ M +AA+L VPL+ E G G+NW++AH
Sbjct: 889 LVAQVSEKIREHMSAAAQLDVPLLVEVGVGNNWDEAH 925