Pairwise Alignments

Query, 934 a.a., DNA polymerase I from Vibrio cholerae E7946 ATCC 55056

Subject, 928 a.a., DNA polymerase I (NCBI) from Escherichia coli BW25113

 Score = 1202 bits (3110), Expect = 0.0
 Identities = 606/935 (64%), Positives = 738/935 (78%), Gaps = 8/935 (0%)

Query: 1   MAHIPDNPLILIDGSSYLYRAFHAYPGTMSNGEIPTNAIYGVVNMIRSMMRQFASDRMAV 60
           M  IP NPLIL+DGSSYLYRA+HA+P   ++   PT A+YGV+NM+RS++ Q+     AV
Sbjct: 1   MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAV 60

Query: 61  IFDAKGKTFRDEMYDQYKAHRPPMPDELRCQVEPLHQVIRAMGLPLLAIEGVEADDVIGT 120
           +FDAKGKTFRDE+++ YK+HRPPMPD+LR Q+EPLH +++AMGLPLLA+ GVEADDVIGT
Sbjct: 61  VFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGT 120

Query: 121 LARQASQAGMPVLISTGDKDMAQLVDDNITLINTMTNVVLDREGVIEKFGIPPELIIDYL 180
           LAR+A +AG PVLISTGDKDMAQLV  NITLINTMTN +L  E V+ K+G+PPELIID+L
Sbjct: 121 LAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTILGPEEVVNKYGVPPELIIDFL 180

Query: 181 ALMGDKVDNIPGVPGVGEKTATALLQGIGGLEALYANLDKIAALGFRGSKTMAQKLEENR 240
           ALMGD  DNIPGVPGVGEKTA ALLQG+GGL+ LYA  +KIA L FRG+KTMA KLE+N+
Sbjct: 181 ALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNK 240

Query: 241 GNAKLSYQLATIKCDVELEESPQTLLKQTPDRDALMSLYGKLAFKSWLTELLDGGTGIVT 300
             A LSYQLATIK DVELE + + L  Q P  + L+ L+ K  FK W  ++ + G  +  
Sbjct: 241 EVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADV-EAGKWL-- 297

Query: 301 ADEQTKTSSVTVSTAATHAA-AIPESPAAHIDRSQYQTILNEQDFQLWLEKLKQAELFAF 359
              Q K +        T  A   PE  A  I    Y TIL+E+  + W+ KL++A +FAF
Sbjct: 298 ---QAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAF 354

Query: 360 DTETDNLDYMVANLVGMSFAVAEGEAAYLPVAHDYLDAPQQLERDWVIAQLKPLLEDESK 419
           DTETD+LD + ANLVG+SFA+  G AAY+PVAHDYLDAP Q+ R+  +  LKPLLEDE  
Sbjct: 355 DTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKA 414

Query: 420 AKVGQNLKYDASVMARYGVELRGIRHDTMLQSYVYNSVGGKHDMDSLALRFLQHSCISFE 479
            KVGQNLKYD  ++A YG+ELRGI  DTML+SY+ NSV G+HDMDSLA R+L+H  I+FE
Sbjct: 415 LKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFE 474

Query: 480 QVAGKGKNQLTFNQIALEEAAQYAAEDADVTLRLHQRIHPLIEQDAKLEQVYREIEMPLV 539
           ++AGKGKNQLTFNQIALEEA +YAAEDADVTL+LH ++ P +++      V+  IEMPLV
Sbjct: 475 EIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLV 534

Query: 540 PVLSRIERTGVMIDDMLLSAQSQEIALRLDQLEQNAYELAGQPFNLSSPKQLQTILFEQM 599
           PVLSRIER GV ID  +L   S+E+ LRL +LE+ A+E+AG+ FNLSS KQLQTILFE+ 
Sbjct: 535 PVLSRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQ 594

Query: 600 KLPVLQKTPSGTPSTNEEVLQELALDYPLPKVLIEYRGLAKLKSTYTDKLPKMINPSTGR 659
            +  L+KTP G PST+EEVL+ELALDYPLPKV++EYRGLAKLKSTYTDKLP MINP TGR
Sbjct: 595 GIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGR 654

Query: 660 VHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFVAPHGWKIMAVDYSQIELRIM 719
           VHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAF+AP  + I++ DYSQIELRIM
Sbjct: 655 VHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIM 714

Query: 720 AHLSGDQALLDAFRDGKDIHAATAAEIIGVPIDQVSSEQRRRAKAVNFGLIYGMSAFGLA 779
           AHLS D+ LL AF +GKDIH ATAAE+ G+P++ V+SEQRR AKA+NFGLIYGMSAFGLA
Sbjct: 715 AHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLA 774

Query: 780 KQLGIPRGEAQEYMDKYFERYPGVMQYMEDTRSRAAQLGYVETIFGRRLHLPEITSRNAM 839
           +QL IPR EAQ+YMD YFERYPGV++YME TR++A + GYVET+ GRRL+LP+I S N  
Sbjct: 775 RQLNIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGA 834

Query: 840 RRKAAERAAINAPMQGTAADIIKKAMLLVDEWIEREGDGRVKLLMQVHDELVFEVKESSL 899
           RR AAERAAINAPMQGTAADIIK+AM+ VD W++ E   RV+++MQVHDELVFEV +  +
Sbjct: 835 RRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAE-QPRVRMIMQVHDELVFEVHKDDV 893

Query: 900 SEIESKVQQLMESAAELAVPLVAEAGHGDNWEQAH 934
             +  ++ QLME+   L VPL+ E G G+NW+QAH
Sbjct: 894 DAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH 928