Pairwise Alignments

Query, 347 a.a., porphobilinogen synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 324 a.a., 5-aminolevulinate dehydratase = porphobilinogen synthase (VIMSS) from Escherichia coli BW25113

 Score =  253 bits (647), Expect = 4e-72
 Identities = 142/320 (44%), Positives = 205/320 (64%), Gaps = 6/320 (1%)

Query: 12  RRLRRLRKHDFSRRLVAENQLSVNDLIYPMFILMGKDRREKVDSMPGVERLSIDLMLEEA 71
           +R RRLRK    R +  E  LS+NDL+ P+F+    D  + V++MPGV R+    +  E 
Sbjct: 6   QRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREI 65

Query: 72  QYLANLGVPAIALFPVVNQDAKSLCAAEAYNPEGLVQRAVRALKEHVPQMGVITDVALDP 131
           + +AN G+ ++  F + +   ++   ++A+  +GLV R  R  K+ VP+M V++D     
Sbjct: 66  ERIANAGIRSVMTFGISHHTDET--GSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCE 123

Query: 132 FTTHGQDGIIDEQGYVLNDETTEVLVKQALSHAQAGADVVAPSDMMDGRIGRIRQALEEA 191
           +T+HG  G++ E G V ND T E L KQA+  A AGAD +APS  MDG++  IRQAL+ A
Sbjct: 124 YTSHGHCGVLCEHG-VDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAA 182

Query: 192 GYIHTQIMAYSAKYASNYYGPFRDAVGSSANLKGGNKKNYQMDPANSDEALHEVAMDINE 251
           G+  T IM+YS K+AS++YGPFR+A GS+     G++K+YQM+P N  EA+ E  +D  +
Sbjct: 183 GFKDTAIMSYSTKFASSFYGPFREAAGSALK---GDRKSYQMNPMNRREAIRESLLDEAQ 239

Query: 252 GADMVMVKPGMPYLDVVRRVKTELQVPTFAYQVSGEYAMHKAAIMNGWLKERETVFESLL 311
           GAD +MVKP   YLD+VR ++   ++P  AYQVSGEYAM K A + G + E + V ESL 
Sbjct: 240 GADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLG 299

Query: 312 CFKRAGADGILTYFAKEVAE 331
             KRAGAD I +YFA ++AE
Sbjct: 300 SIKRAGADLIFSYFALDLAE 319