Pairwise Alignments

Query, 454 a.a., MATE family efflux transporter from Vibrio cholerae E7946 ATCC 55056

Subject, 547 a.a., putative multdrug exporter, MATE family from Escherichia coli BL21

 Score = 89.0 bits (219), Expect = 4e-22
 Identities = 107/453 (23%), Positives = 196/453 (43%), Gaps = 38/453 (8%)

Query: 18  RQVLAIALPMVLSNITVPLLGLVDAAVIGHLEHAWYLGGVALGSTMISVTFWLLGFLRMS 77
           R++  +A+P+ + N  V L+G++   ++  L     + GV L  +   V       + + 
Sbjct: 92  REITPLAVPIFMENACVLLMGVLSTFLVSWLGKD-AMAGVGLADSFNMVIMAFFAAIDLG 150

Query: 78  TTGLTAQAHGAQNSQQLARVLLQGSVIALGLAALFL--LFHRPVAELI-FHFSDASSEVK 134
           TT + A + G ++ ++ ARV  + S++ + L A+ L  L H    ++I F   DA++EVK
Sbjct: 151 TTVVVAFSLGKRDRRR-ARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVK 209

Query: 135 TYAEAYFYIRAWSAPAALLNFVLLGWLLGTQNARAPMWMVIITNLTNIVLDLLLVLGL-- 192
             A  Y  +   S PAA +  +  G L G  N + P+ +    N+ NI++  +L+ GL  
Sbjct: 210 ALALTYLELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFS 269

Query: 193 --GLKVEGAAIASVIADYAG--LLFGLLCVGRYWRQHQLPAPFSFIPSLTKELSRLVALN 248
             GL   GA +   I+ Y G   +  +L +G +    ++     F P     +  ++ + 
Sbjct: 270 WPGLGFVGAGLGLTISRYIGAVAILWVLAIG-FNPALRISLKSYFKPLNFSIIWEVMGIG 328

Query: 249 RDIFLRSLCLQAVFSFMTFQGAALGDDIVAANAVLMSFLMMISYGMDGFAYAMEAMVGKA 308
               + S+   +         A +G  ++A N +  S   +I+        A   + G+ 
Sbjct: 329 IPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRR 388

Query: 309 IG----AKDDRQLRTAMISSTFWATMICLLLSLIFLGFGSDLIQMITNIPSVQATAEHYL 364
           +G    A+ + QLR     ST   T I  L +     F   +    T  P V+      L
Sbjct: 389 LGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTA----PFAGVMASFYTQDPQVKHVVV-IL 443

Query: 365 PWLVAMPLIAVW--CFLLDGVFIGATKGKEMRNSMAVSAVAFFA-------IYGFMTHYG 415
            WL A+  + +W   ++L   F GA   ++ R +M VS ++ +        + G M  +G
Sbjct: 444 IWLNAL-FMPIWSASWVLPAGFKGA---RDARYAMWVSMLSMWGCRVVVGYVLGIMLGWG 499

Query: 416 NHALWLAMLSFMALRGFTLGATFYTQWRAGTFL 448
              +W+ M +  A+R       FY +   G +L
Sbjct: 500 VVGVWMGMFADWAVR----AVLFYWRMVTGRWL 528