Pairwise Alignments

Query, 645 a.a., phosphomethylpyrimidine synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 630 a.a., thiamine biosynthesis protein ThiC from Pseudomonas simiae WCS417

 Score =  903 bits (2333), Expect = 0.0
 Identities = 443/624 (70%), Positives = 512/624 (82%), Gaps = 17/624 (2%)

Query: 15  IDTLSVEPYPNSQKSYLLGSRPDIRVPVREITL--SDTLVGGSKDAPIFEPNEPICVYDT 72
           +D+ SV+P+  SQK Y+ G+RPDIRVP+REI+L  + T  GG       E N P+ VYDT
Sbjct: 18  VDSGSVQPFTRSQKIYVQGTRPDIRVPMREISLDVTPTDFGG-------EINAPVTVYDT 70

Query: 73  SGVYTDPSHDIDLYKGLPKLREEWIEERRDTHILPSMSSHFARERLADETLDELRYGHLP 132
           SG YTDP+  ID+ KGL  +R  WIE R DT  LP +SSHF ++RL+D  L  LR+ H+ 
Sbjct: 71  SGPYTDPNVIIDVRKGLADVRSPWIEVRNDTERLPGLSSHFGQQRLSDAELTALRFAHVK 130

Query: 133 RIRRAMGQHRVTQLHYARQGIITPEMEFVAIRENSRRLAHQDPSLL-QQHAGQNFGAHLP 191
             RRA     VTQ+HYAR+GIIT EME+VAIREN +    +   LL QQHAG +FGA +P
Sbjct: 131 NPRRAKAGANVTQMHYARKGIITAEMEYVAIRENMKLEEARATGLLDQQHAGHSFGASVP 190

Query: 192 DLITPEFVRREIAEGRAIIPCNINHPESEPMIIGRNFLVKVNANIGNSSVSSSIEEEVEK 251
            +ITPEFVR EIA GRAIIP NINH E EPMIIGRNFLVK+N NIGNS++ SSIEEEV K
Sbjct: 191 KIITPEFVREEIARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAK 250

Query: 252 LVWATRWGADTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLTWEVM 311
           L W  RWG+DTVMDLSTG++IHETREWI+RNSPVPIGTVP+YQALEKV G AE+LTWE+ 
Sbjct: 251 LTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGAAEDLTWELF 310

Query: 312 RDTLLEQAEQGVDYFTIHAGLLLRYVPMTAKRVTGIVSRGGSIIAKWCLSHHQENFLYTH 371
           RDTL+EQAEQGVDYFTIHAG+LLRYVP+TAKRVTGIVSRGGSI+AKWCL+HH+ENF YTH
Sbjct: 311 RDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFTYTH 370

Query: 372 FREICEICAQYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTQIAWEYDVQVMIEGP 431
           F EICEI   YDV+ SLGDGLRPGSIADAND AQF EL TLGELT+ AW++DVQ MIEGP
Sbjct: 371 FDEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKTAWKHDVQTMIEGP 430

Query: 432 GHVPMHLIKANMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCY 491
           GHVPM LIK NMD+QL+ C EAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCY
Sbjct: 431 GHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCY 490

Query: 492 VTPKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNL 551
           VTPKEHLGLPNK+DVKTG+ITYK+AAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNL
Sbjct: 491 VTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNL 550

Query: 552 ALDPVTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYANNQTLDTTVIDLVM 611
            LDP TAR++HDETLP++S KVAHFCSMCGPKFCSMKI+QEVR+YA NQ ++   +D   
Sbjct: 551 GLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIEAVDVD--- 607

Query: 612 PAESIQLAMQDKSREFLASGAELY 635
               +   + ++++ F   G++LY
Sbjct: 608 ----VAKGLAEQAQRFKQEGSQLY 627