Pairwise Alignments

Query, 190 a.a., DNA topoisomerase from Vibrio cholerae E7946 ATCC 55056

Subject, 873 a.a., DNA topoisomerase I from Pseudomonas simiae WCS417

 Score = 45.1 bits (105), Expect = 4e-09
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)

Query: 21  SSPCPQCGAALQLRHGKHGPFLGCTAYPECDYIKPLHQNDGHI------IKELGVPCPEC 74
           S  C +CG+ +QL+ G+ G F GCT  P C   + L ++          +K   + C + 
Sbjct: 712 SLECDKCGSEMQLKTGRFGKFFGCTN-PTCKNTRKLLKSGDAAPPKMDPVKMPELKCEKV 770

Query: 75  GHELVLRQGRYGMFIGCSHYPQ 96
               +LR G  G+F+  S +P+
Sbjct: 771 NDTYILRDGASGLFLAASQFPK 792



 Score = 43.1 bits (100), Expect = 1e-08
 Identities = 40/152 (26%), Positives = 59/152 (38%), Gaps = 23/152 (15%)

Query: 14  AHEHALQSSPCPQCGAALQLRHGKHGPFLGCTAY-----PECDYIKPLHQNDGHIIKELG 68
           A++  +   PC  CG  +Q+R    G FLGC+ Y       C     L   D     + G
Sbjct: 594 ANQPVMTDIPCQTCGRPMQIRTASTGVFLGCSGYSLPPKERCKATVNLVPGDEIAADDEG 653

Query: 69  VP----------CPEC--GHELVLRQGRYGMFIGCSHYPQC--HHIESMDSPSQEETSPD 114
                       CP C    +  L   ++ + I C + P C  + IE      +    P 
Sbjct: 654 ESESLVLRGKHRCPICSTAMDAYLLDEKHKLHI-CGNNPDCNGYEIEEGTYRIKGYEGPS 712

Query: 115 ILCPECGKGHLIERKSRFGKLFYACDAYPKCK 146
           + C +CG   +  +  RFGK F+ C   P CK
Sbjct: 713 LECDKCG-SEMQLKTGRFGK-FFGC-TNPTCK 741