Pairwise Alignments

Query, 483 a.a., Na+-driven multidrug efflux pump from Sphingobium sp. HT1-2

Subject, 445 a.a., MATE family efflux transporter from Vibrio cholerae E7946 ATCC 55056

 Score = 93.6 bits (231), Expect = 1e-23
 Identities = 88/431 (20%), Positives = 180/431 (41%), Gaps = 17/431 (3%)

Query: 23  FAIPTLASNILQSLNGSINAIWVGRFLGPQALAATANANIIMFLMFSVVFGFGMASTVMI 82
           + IPT+A+ ++  L   ++ I++G ++G + LA    A  ++  +  +    G+ +  + 
Sbjct: 13  YTIPTVAAMLVNGLYQVVDGIFIGHYVGAEGLAGINVAWPVIGTILGIGMLVGVGTGALA 72

Query: 83  AQAVGARDMDAARRAFGSAVGFCFLLAMGVAVAGWFGGPALLHLLATPPEAFDMALTYLR 142
           +   G    D+A+R   + +    LLA  VAV  WF     L         F++ L YL+
Sbjct: 73  SIKQGEGHPDSAKRILATGLMSLLLLAPIVAVILWFMADDFLRWQGAEGRVFELGLQYLQ 132

Query: 143 VIFVAMPASLLSVMMMMGLRGTGDARTPLIFMILSVAIDLVLNPVLILGLGPIPAMGIGG 202
           V+ V    +L S+ M   LR         + M++    ++ L+ + I  L       + G
Sbjct: 133 VLIVGCLFTLGSIAMPFLLRNDHSPNLATLLMVIGALTNIALDYLFIAWL----QWELTG 188

Query: 203 SAAATAAAGFVSLIALVIYTYAKDLPLRLRGAELGYLRPAMDEMRVLSTKGLPMGLQMIV 262
           +A AT  A  V  +  + Y ++    +RL    L     ++ ++         +G+    
Sbjct: 189 AAIATTLAQVVVTLLGLAYFFSARANMRLTRRCLRLEWHSLPKI-------FAIGVSSFF 241

Query: 263 MSTSGLVMIGLVNR-----EGFLVTAAYGAAQQIWTYLQMPAMAMGAAVSAMAAQNIGAG 317
           M   G  M+ L N         ++  AY     I T   +    +   +  +A+ + GA 
Sbjct: 242 MYAYGSTMVALHNTLMIEYGNAVMVGAYAVMGYIVTIYYLTVEGIANGMQPLASYHFGAR 301

Query: 318 RWDRISRITGYGISYLLAITGAMVVVILIFHEALLALFLSHNQAVIDAAWNMQLLASWSF 377
            +D I ++    +   +    A V+V+ +F E  +A+F S +  +I  A     L  ++ 
Sbjct: 302 NYDHIRKLLRLAMGIAVLGGMAFVLVLNLFPEQAIAIFNSSDSELIAGAQMGIKLHLFAM 361

Query: 378 MLFGCTMILFGVMRANGVVVAPLLILVFTLFAVRLGFYYLAYPRIGADALWLSFPVGSAV 437
            L G  ++     ++       + I V  + ++ L F ++     G   +W++ P+ + V
Sbjct: 362 YLDGFLVVSAAYYQSTNRGGKAMFITVGNM-SIMLPFLFILPQFFGLTGVWIALPISNIV 420

Query: 438 SLTLAALVYWQ 448
             T+  ++ W+
Sbjct: 421 LSTVVGIMLWR 431