Pairwise Alignments

Query, 461 a.a., Fumarate hydratase class II (EC 4.2.1.2) from Sphingobium sp. HT1-2

Subject, 461 a.a., class II fumarate hydratase from Vibrio cholerae E7946 ATCC 55056

 Score =  355 bits (912), Expect = e-102
 Identities = 200/457 (43%), Positives = 282/457 (61%), Gaps = 9/457 (1%)

Query: 5   RTETDSIGAIEVPADAYWGAQTQRSIENFPFGATERMPIGIVHAQAIVKQAAARVNAKHG 64
           R E DS+G ++VPADA + AQTQR+++NF   +   MP   + A A +KQAAA  NA+ G
Sbjct: 6   RIEKDSMGEVKVPADALYQAQTQRAVDNFTL-SRYTMPSAFIAALAYIKQAAAMTNAQLG 64

Query: 65  -LDAKIVAGIENAAQQIVSGALDDQFPLVIWQTGSGTQTNMNVNEVIAGYANEQLAGTRG 123
            L+  I   I NA+Q ++ G    QFP+ ++QTGSGT +NMN NEVIA  A+ +L     
Sbjct: 65  HLEGDIAQAIANASQAVIDGQYAKQFPIDVFQTGSGTSSNMNANEVIATLASRELGYA-- 122

Query: 124 GKSPVHPNDHVNMSQSSNDSFPTALHVATVLATRDKLIPALEKLTGALTAKAEGWGHIVK 183
               V PNDHVNM QSSND  PTA+ V+  +    +L+PAL  L+  L  K      +VK
Sbjct: 123 ----VSPNDHVNMGQSSNDVIPTAIQVSAAINIEQQLLPALAHLSQTLADKQSELADVVK 178

Query: 184 IGRTHTQDATPLTLGQEFSGYAAQLVSSKARIEGVLNGNIRKLAIGGTAVGTGLNAPDGW 243
            GRTH  DA P+T  QE  G+ +Q+  +   I   L+  I+ LA GGTAVGTG+NA   +
Sbjct: 179 TGRTHLMDAMPVTFAQELGGWKSQIDHAAQGISHALSP-IKALAQGGTAVGTGINADPRF 237

Query: 244 ADDMTAAISDIAGTSFESAPNKFEQLAAKDGLVFFSGALNTLAVALTKIANDIRFLGSGP 303
           A      +S ++  +F+ + N F  L+++D +V  SG L T AVAL KIAND+R++ SGP
Sbjct: 238 ARIFADNLSQLSHVAFQPSDNFFYNLSSQDCVVGLSGQLKTAAVALMKIANDLRWMNSGP 297

Query: 304 RSGLGELDLPANEPGSSIMPGKVNPTQCESLTMVAAQVIGNHQAVTVGGMQGHFELNVFM 363
            +GLGE++L   +PGSSIMPGKVNP   E++TMVAAQVIGN   +TV G  G+F+LNV +
Sbjct: 298 LAGLGEIELQGLQPGSSIMPGKVNPVIPEAVTMVAAQVIGNDTTITVAGQSGNFQLNVML 357

Query: 364 PLIGANVLRSIHLLSVGMESFADRCVEGMQANEGRIAELVERSLMLVTALAPEIGYDNAA 423
           P+I  N+L SI LL+    + AD+ +   +     + + + ++ +LVTAL P IGY  AA
Sbjct: 358 PVIAHNLLESIELLTNACHALADKAIATFKVRHDNLEKALAKNPILVTALNPVIGYLKAA 417

Query: 424 TIAKHAHKKGLTLKQAGLELGLVDEPTFDRLVRPENM 460
            IAK A+++G  +     E   +D  T + L+ P+ +
Sbjct: 418 DIAKKAYQQGRAILDVAAEETDLDRATLEALLDPKKL 454