Pairwise Alignments

Query, 737 a.a., isoquinoline 1-oxidoreductase from Sinorhizobium meliloti 1021

Subject, 772 a.a., dehydrogenase from Sinorhizobium meliloti 1021

 Score =  103 bits (256), Expect = 4e-26
 Identities = 103/402 (25%), Positives = 165/402 (41%), Gaps = 55/402 (13%)

Query: 207 DWKLIGNDELKRFDSARKANGTEQYTIDVKLPGMLTAVMIHPPLFGAKAKSFDASAARAI 266
           D+ ++G   +KR D+  K  GT +Y  DV LPGML A M    +  A+ +S D S A A+
Sbjct: 15  DFTVVGKS-VKRSDTLEKVTGTARYAGDVALPGMLHAKMKRSNIAHARIRSIDTSKALAL 73

Query: 267 KGVVDVV---ETPRGIAVVGEHMWAAIKGREAVTVE-----WDE---------------- 302
           KGV  V+   + PR +     H  +A   ++   ++     W E                
Sbjct: 74  KGVKAVLTHEDVPRVLHAGSPHPRSASVTKDQYILDDRVRYWGEGVAAVAAVSEEIAERA 133

Query: 303 -----------------TGAEKRGTPELMSTYRDLAGKSPAAFARKDGDTDAAFTSAAKV 345
                              A   G P +     D     P  F  + GD D  F  A  +
Sbjct: 134 VALIEVEYEPLPGLFTIEAASVPGAPPIHENGLDRNQVLPPVFVTR-GDVDRGFAEADLI 192

Query: 346 IEATFEFPYLAHAALEPLNAVARRNDDGTIEIWGGHQLPDVYQNLASEIAGVPVEKVRLN 405
           +E  ++      A +EP   V++ + +G + +W   Q   + +   +E+ GVP+ KVR+ 
Sbjct: 193 LEREYDLGRPTPAYMEPNVCVSQWDGNGKLTMWTSTQSAFMVRGTLAEVLGVPLNKVRVI 252

Query: 406 VMKTGGSFG-RRAVFDGDVVVEAVHVAKALGFRAPVKVQWTREEDTRAGRYRPAYVHRLK 464
           V   GG FG ++ +F  + +     +A+  G   PVK++++R+E    GR R      LK
Sbjct: 253 VDHMGGGFGAKQDLFQNEFL--CALLARQTG--RPVKMEFSRKETFLGGRSRHPGKIWLK 308

Query: 465 AGIDEAGKLVAWSDHIVGQSIMAKTAWDGMVQNGVDPTSVEGANNLPYAIANQTVGLTTT 524
            G  + G++VA    +   S    +   G+   G        A    Y   N  +     
Sbjct: 309 QGFTKDGRIVAREARVTFNSGAYGSHGPGVTNVGT------AALTSLYRCENVRLEGRCI 362

Query: 525 DVRVPVLW-WRSVGSTHTAFAAEAFLDEVAEAAGRDPLEFRL 565
               P+   +R  G   T +A +  +DE AE  G DP EF+L
Sbjct: 363 YTNSPIAGAFRGYGVVQTYYALDLMMDEAAEKLGFDPAEFKL 404



 Score = 67.4 bits (163), Expect = 3e-15
 Identities = 50/135 (37%), Positives = 69/135 (51%), Gaps = 12/135 (8%)

Query: 607 SVVAQIAEVSVDGDG--IKVERVVAAVDCGLAINPDQVRAQVEGGIGFGLSAILGEE--I 662
           S  A  AEV VD +   + V +VV   + G  I+P     Q+EGGI  G+   L E+  I
Sbjct: 620 SFAAHFAEVEVDTETGEVAVLQVVPVHEIGRVIHPIAAAGQIEGGIQQGIGHTLSEDYVI 679

Query: 663 TLTDGKVDQGNF-DMYTPLRIDAMPKVEVHIVASANPP------SGIGEPGVPPIGPAVA 715
            LTDG+    +F D   PL +D MP +   I+ +A  P       G+GE  +  IGPA+A
Sbjct: 680 DLTDGRSLNPSFVDYKMPLSMD-MPSIRTIILETAPDPGGPYGAKGVGEDPIIAIGPAIA 738

Query: 716 NAAFKALGKRIRVMP 730
           NA + A+G R    P
Sbjct: 739 NAIYDAIGVRFHHYP 753



 Score = 37.4 bits (85), Expect = 3e-06
 Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 8/130 (6%)

Query: 69  DGKVTVLSSQFEMGQGSYNGIATLVAEELDSDWSAIDVIGAAGNIKAYGNIAFGGTMQGT 128
           DG VT+++    +G G++  ++ +VAEEL   + A+ V+    +I  +   AF       
Sbjct: 483 DGTVTLITGTAGLGTGAHTALSQIVAEELGVPFEAVSVVQGDTDIVPWDIGAFASHTTYL 542

Query: 129 GGSTSMSTSWERYRRAGAAARAMLVAAAAAEWGVDAAEIAVENGVLSHPSGKSGGFGAFA 188
           GG  +        + A A  R  ++  AA     +   +A+ +G +   +G +       
Sbjct: 543 GGRAA--------QLAAADVRRQVLEHAAPMLKAEPENLAIRDGFVVVTNGSNRSIRLSE 594

Query: 189 AKAATMPVPA 198
           A      +PA
Sbjct: 595 AVGPQRGMPA 604