Pairwise Alignments
Query, 1048 a.a., CzcA family heavy metal efflux protein (RefSeq) from Shewanella amazonensis SB2B
Subject, 1064 a.a., CusA/CzcA family heavy metal efflux RND transporter from Ralstonia solanacearum UW163
Score = 617 bits (1592), Expect = e-180
Identities = 364/1054 (34%), Positives = 591/1054 (56%), Gaps = 30/1054 (2%)
Query: 1 MLDYIIKSSIRQRFMVLVVALMVTLWGITELKRTPLDALPDLSDVQVIIKTSFPGQAPQL 60
M + ++++ I QR++VL+ L +G R +DA+PD+++VQV I T PG +P
Sbjct: 1 MFERLLRAVIAQRWLVLLAVLGAAAYGAYSYTRLSIDAVPDITNVQVQINTPAPGYSPLE 60
Query: 61 VEEQVTYPLSTAMLAVPGAKTVRGFSMFGDSYVYVIFEDGTDIYWARSRVLEYLSQVRTR 120
E+++TYPL TAM +P + R S +G S V VIF++GTDIY+AR V E L + +
Sbjct: 61 TEQRITYPLETAMAGLPKLEQTRSLSRYGLSQVTVIFKEGTDIYFARQLVSERLQAAKEQ 120
Query: 121 LPAGVEPSLGPDASGVGWVYEYALVDRSG-------NLDLSQLKSLQDWYLKLELQSVEG 173
LP GV P +GP A+G+G +Y + + +G + L+ LQDW ++ ++++V G
Sbjct: 121 LPDGVSPGMGPVATGLGEIYLWTVEADAGARKPDGTAYTPADLRELQDWVIRPQIRNVPG 180
Query: 174 VSEVATVGGMEQTYQIVLEPDKLAIYKLDIATIKAAITRANSEAGGSVVEMAEAEYMVRA 233
V+EV T+GG + + + P++LA YKL +A I AA+ R N+ G +E +Y+VRA
Sbjct: 181 VTEVNTIGGFAKEFLVATSPERLASYKLTLADIVAALERNNANVGAGYIERRGEQYLVRA 240
Query: 234 KGYRQTLDDFREIPLGITTGAGTPLLLKDVATIRKGPASRRGIAELDGEGEVVGGIIVMR 293
G + D + I + GTP+ L+DVA I G R G A +G E V G V+
Sbjct: 241 PGQLRDAADIGNVV--IASPNGTPVRLRDVAAIESGSELRTGAATSNGR-EAVLGTAVLL 297
Query: 294 YGENALATIDAVKAKLDELKAGLPDGVEIVPTYDRSQLIQNSVDNLLTKVVEEMLVVGLV 353
GEN+ AV ++ +++ LP GV + YDR+ L+ ++ + ++E ++V V
Sbjct: 298 MGENSRTVAQAVDKRIQDIRRTLPAGVRVETVYDRTVLVDKAIATVKKNLLEGAILVMAV 357
Query: 354 CLLFLLHARSTLVAVFTLPLSILIAFIVMNHMGINANIMSLGGIAIAIGAVVDGAIVMIE 413
LFL + R+ ++ +PLS+L+ F M ++AN+MSLG A+ G +VDGA+V++E
Sbjct: 358 LFLFLGNLRAAVLTALVIPLSMLMTFSGMVSAKVSANLMSLG--ALDFGIIVDGAVVIVE 415
Query: 414 NLHKHLEHFKRQHEREPSTREHWEVVTQASLEVGPALFFSLLIITLSFIPVFALEAQEGR 473
N + L H + R + E +E V QA+ E L + LII + ++P+FAL EG+
Sbjct: 416 NCVRRLAHAQHGLGRPLTRAERFEEVFQAAREARRPLLYGQLIIMVVYLPIFALSGVEGK 475
Query: 474 LFAPLAYTKTFAMAAASVLAITLVPVLMGYFIRGKIPSEEANPISRFLIALYKPALNKVL 533
+F P+A T A+AAA VL++T VP + + G+ +E+ N + + +Y P L + L
Sbjct: 476 MFHPMAITVVLALAAAMVLSVTFVPAAVALGM-GERVAEKENRLMGWARRMYAPLLERAL 534
Query: 534 AFPKLTLLVALLALASVVYPASRMGSEFMPELEEGDLLYMPTALPGISAGKAAEILQQTD 593
A P + L A +A++ + A R+G+EF+P L EGDL +PG ++ E+ Q +
Sbjct: 535 AAPAVVLTFAAVAVSVSLVAAFRLGAEFVPNLNEGDLSIQAMRVPGTGLAQSLEMQMQIE 594
Query: 594 RLIKT-VPEVARVFGKIGRAETATDPAPLTMLETTIMLKPRQEWREG-----INLNDIVD 647
R +K PE+ARVF + G AE ATD P ++ + IML+P ++W G + + ++
Sbjct: 595 RTLKAKFPEIARVFARTGTAEIATDVMPPSISDGYIMLRPERDWPAGPDGRRRDRDQLLA 654
Query: 648 ELQRTVK-VPGLTNAWVQPIKTRIDMLSTGIKTPVGIKITGANVDELQQIGANVEAILAA 706
E++ TV+ +PG + QPI+ R + L +G+++ V +K+ G ++ L++ V A L
Sbjct: 655 EIRATVEALPGNAYEFSQPIQLRFNELISGVRSDVAVKLFGDDMAVLEKQAQAVAAQLNR 714
Query: 707 LPNTRSAYAERAGGGRYIDIAPKLDVASRYGMTLNDIQDVVRYAIGGMNVGESVQGAERY 766
L E+ GG +++I + A+RYG+ + IQD V AIGG + G QG R+
Sbjct: 715 LAGAAEVKIEQTGGLPFLNIDIDREKAARYGLAIGVIQDTVSAAIGGKDAGTVFQGDRRF 774
Query: 767 PINLRYPRELRDSLEKLRALPVITKSGH-YLPLGNLADIQISDGPPMLKSENGRLISWVF 825
I +R P R L LP+ +G Y+PL +A + + GP + E+G+ V
Sbjct: 775 GIVVRLPEAARSDPAALGRLPLALPNGQGYVPLSEVAVLHEATGPNQVSREDGKRRIVVS 834
Query: 826 VDIQGTSIGEYIQTAKSALEAELNLPPRYSYSFAGQYEYMQRVDAKLKQVVPLAIGIIFI 885
+++G I ++Q A+ AL+A++ LP Y ++ GQ+E +Q +L+ VVPLA+ ++F
Sbjct: 835 ANVRGRDIASFVQEAQGALDAQIRLPAGYWMTWGGQFEQLQSATERLRVVVPLALALVFT 894
Query: 886 LLMLTFGSGKQASMIMLSLPFALVGSTWLLYLLDYNLSVAVAVGMIALAGVAAEFGVVML 945
LL + FG+ K ++ +PFAL G L L LS++ AVG IAL+GVA G+VML
Sbjct: 895 LLFMMFGNLKDGLLVFSGIPFALSGGIVALALRGIPLSISAAVGFIALSGVAVLNGLVML 954
Query: 946 VYLNNAIKDRDALGHYHNESDLKAALVEGAVMRIRPKAMTVATIFFGLLPIMWGAGSGNE 1005
++ + + A+ EGA+ R+RP MT G +P+ G+G E
Sbjct: 955 SFIRSL---------REGGKPVDEAVREGALTRLRPVLMTALVASLGFVPMALATGTGAE 1005
Query: 1006 VMQKIAAPMVGGMVTAPLLSLFVLPALYLLVYRK 1039
V + +A ++GG++++ L+L VLP LY L YR+
Sbjct: 1006 VQRPLATVVIGGILSSTALTLLVLPVLYRLAYRR 1039
Score = 42.7 bits (99), Expect = 1e-07
Identities = 110/559 (19%), Positives = 222/559 (39%), Gaps = 83/559 (14%)
Query: 524 LYKPALNKVLAFPKLTLLVALLALASVVYPASRMGSEFMPELEEGDLLYMPTALPGISAG 583
+++ L V+A L LL L A A Y +R+ + +P++ + + T PG S
Sbjct: 1 MFERLLRAVIAQRWLVLLAVLGAAAYGAYSYTRLSIDAVPDITNVQV-QINTPAPGYSP- 58
Query: 584 KAAEILQQTDRLIKTVPEVARVFGKIGRAETATDPAPLTMLETTIMLKPRQEWREGINL- 642
L+ R+ T P + G + + E + + + T++ K EG ++
Sbjct: 59 -----LETEQRI--TYPLETAMAG-LPKLEQTRSLSRYGLSQVTVIFK------EGTDIY 104
Query: 643 --NDIVDELQRTVK--VPGLTNAWVQPIKTRIDML-------STGIKTPVGIKITGANVD 691
+V E + K +P + + P+ T + + G + P G T A++
Sbjct: 105 FARQLVSERLQAAKEQLPDGVSPGMGPVATGLGEIYLWTVEADAGARKPDGTAYTPADLR 164
Query: 692 ELQQIGANVEAILAALPNTRSAYAERAGGG--RYIDIAPKLDVASRYGMTLNDIQDVVRY 749
ELQ I + N GG + +A + + Y +TL DI +
Sbjct: 165 ELQDW-----VIRPQIRNVPGVTEVNTIGGFAKEFLVATSPERLASYKLTLADIVAALER 219
Query: 750 AIGGMNVGESVQGAERYPINLRYPRELRDSLEKLRALPVITKSGHYLPLGNLADIQ---- 805
+ G + E+Y + R P +LRD+ + + + + + +G + L ++A I+
Sbjct: 220 NNANVGAGYIERRGEQYLV--RAPGQLRDAAD-IGNVVIASPNGTPVRLRDVAAIESGSE 276
Query: 806 ------ISDGPP-------MLKSENGRLISWVFVDIQGTSIGEYIQTAKSALEAELNLPP 852
S+G +L EN R ++ ++ + IQ + L A + +
Sbjct: 277 LRTGAATSNGREAVLGTAVLLMGENSRTVA--------QAVDKRIQDIRRTLPAGVRVET 328
Query: 853 RYSYSFAGQYEYMQRVDAKLKQVVPLAIGIIFILLMLTFGSGKQASMIMLSLPFALVGST 912
Y + + + A +K+ + ++ +L L G+ + A + L +P ++
Sbjct: 329 VYDRTVL-----VDKAIATVKKNLLEGAILVMAVLFLFLGNLRAAVLTALVIPLSM---- 379
Query: 913 WLLYLLDYNLSVAVAVGMIALAGVAAEFGVVM---LVYLNNAIKD----RDALGHYHNES 965
L+ ++ V+ V ++ A +FG+++ +V + N ++ + LG +
Sbjct: 380 ----LMTFSGMVSAKVSANLMSLGALDFGIIVDGAVVIVENCVRRLAHAQHGLGRPLTRA 435
Query: 966 DLKAALVEGAVMRIRPKAMTVATIFFGLLPIMWGAGSGNEVMQKIAAPMVGGMVTAPLLS 1025
+ + + A RP I LPI +G ++ +A +V + A +LS
Sbjct: 436 ERFEEVFQAAREARRPLLYGQLIIMVVYLPIFALSGVEGKMFHPMAITVVLALAAAMVLS 495
Query: 1026 LFVLPALYLLVYRKRFAAK 1044
+ +PA L +R A K
Sbjct: 496 VTFVPAAVALGMGERVAEK 514