Pairwise Alignments
Query, 1048 a.a., CzcA family heavy metal efflux protein (RefSeq) from Shewanella amazonensis SB2B
Subject, 1064 a.a., Cation efflux system protein CzcA from Alteromonas macleodii MIT1002
Score = 640 bits (1651), Expect = 0.0
Identities = 369/1064 (34%), Positives = 598/1064 (56%), Gaps = 43/1064 (4%)
Query: 1 MLDYIIKSSIRQRFMVLVVALMVTLWGITELKRTPLDALPDLSDVQVIIKTSFPGQAPQL 60
M + I+ ++ R +V + + +T+ + R LDA PD+++VQV + T PG A +
Sbjct: 1 MFNRIVDWAVTNRLLVAIALITLTVSAFFIIPRLNLDAFPDVTNVQVSVNTEAPGLAAEE 60
Query: 61 VEEQVTYPLSTAMLAVPGAKTVRGFSMFGDSYVYVIFEDGTDIYWARSRVLEYLSQVRTR 120
VE+ +TYP+ M A+P + VR S G S V V+F++GTDIY+AR V E L +
Sbjct: 61 VEQLITYPIEAVMYALPDVEEVRSISKTGLSGVTVVFKEGTDIYFARQLVFERLQAAKEL 120
Query: 121 LPAGV-EPSLGPDASGVGWVYEYALVDRSGN-LDLSQLKSLQDWYLKLELQSVEGVSEVA 178
+P GV P +GP+ SG+G VY+Y LV G+ D +L+SL DW +KL L EGV++V
Sbjct: 121 IPEGVGTPEMGPNTSGLGQVYQYLLVAEPGSGFDAMELRSLNDWVVKLLLIPAEGVTDVL 180
Query: 179 TVGGMEQTYQIVLEPDKLAIYKLDIATIKAAITRANSEAGGSVVEMAEAEYMVRAKGY-- 236
+ GG + YQ+ L P KL Y L I AA+ R N+ GG + + + ++R G+
Sbjct: 181 SFGGEVRQYQVDLNPSKLLSYDLTQDDIMAALERNNTNVGGWYMNRGQEQLVIRGTGWLD 240
Query: 237 --RQTLDDFREIPLGITTGAGTPLLLKDVATIRKGPASRRGIAEL-----DGE----GEV 285
+Q L+ R++PL T GT + + DVA + G R+G + DG+ GEV
Sbjct: 241 HGKQGLEQIRQVPL--KTVDGTTITVSDVAKVNLGSEIRQGAVTMTRRTSDGKVETLGEV 298
Query: 286 VGGIIVMRYGENALATIDAVKAKLDELKAGLPDGVEIVPTYDRSQLIQNSVDNLLTKVVE 345
V GI++ R G N +TID V A+++ + LP+GV+ YD++ L+ +VD ++ ++
Sbjct: 299 VSGIVLKRLGANTKSTIDGVNARIERINQALPEGVKFEAYYDQADLVTQAVDTVVNALLL 358
Query: 346 EMLVVGLVCLLFLLHARSTLVAVFTLPLSILIAFIVMNHMGINANIMSLGGIAIAIGAVV 405
+ + ++ LFL++ R+TL+ + ++P+SI IA +VM G++AN+MSLGGIA+AIG +V
Sbjct: 359 AFVFIVVILALFLMNLRATLLVLISIPISIGIALMVMAWFGLSANLMSLGGIAVAIGMLV 418
Query: 406 DGAIVMIENLHKHLEHFKRQHEREPSTREHWEV---------------VTQASLEVGPAL 450
DG++VM+EN+ KHL H H+++ T + + +A EV +
Sbjct: 419 DGSVVMVENMFKHLTHPDATHDKDRQTMVQDDPDPVDAAHDSHGIALRLQEAGREVARPI 478
Query: 451 FFSLLIITLSFIPVFALEAQEGRLFAPLAYTKTFAMAAASVLAITLVPVLMGYFIRGKIP 510
FF+ II + F+P+F+ E E +LF P+A + +M +A V+A+ +VP L Y R I
Sbjct: 479 FFATAIILVVFMPLFSFEGVEAKLFQPMAISIMLSMLSALVVALIIVPALATYLFRKGIR 538
Query: 511 SEEANPISRFLIALYKPALNKVLAFPKLTLLVALLALASVVYPASRMGSEFMPELEEGDL 570
E+ + + L LY+ L+ ++ K+ + +A+ + + R+G+EF+PELEEG +
Sbjct: 539 PRESF-VLKPLDKLYRKGLSWAMSHSKVVVGIAVTLVVAAALVIPRLGTEFVPELEEGTV 597
Query: 571 LYMPTALPGISAGKAAEILQQTDRLIKTVPEVARVFGKIGRAETATDPAPLTMLETTIML 630
T P S A E+ + + ++ PEV +IGRAE DP P+ +E I L
Sbjct: 598 NLRVTLAPSSSLDTALEVAPKLEAMLMEFPEVTYALSRIGRAEIGGDPEPVNNIEIYIGL 657
Query: 631 KPRQEWREGINLNDIVDELQRTVKV-PGLTNAWVQPIKTRIDMLSTGIKTPVGIKITGAN 689
KP EW N ++ +++ ++ PGL + QPI TR+D L +G+K + IK+ G +
Sbjct: 658 KPVPEWTSADNRYELQSLMEQKLEQHPGLLFNFSQPIATRVDELLSGVKAQLAIKLFGKD 717
Query: 690 VDELQQIGANVEAILAALPNTRSAYAERAGGGRYIDIAPKLDVASRYGMTLNDIQDVVRY 749
+D L + G +EA++ + TR E+ G + + P SRYG+ + D+ +VVR
Sbjct: 718 LDVLAEKGQAIEAVVKKIDGTRDVAMEQIVGEAQLVVKPNRRALSRYGLDVADVMEVVRN 777
Query: 750 AIGGMNVGESVQGAERYPINLRYPRELRDSLEKLRALPVITKSGHYLPLGNLADIQISDG 809
+GG + G+ + G ERY I +R R E + L + SG ++ LG++A + I+ G
Sbjct: 778 GLGGASAGQIINGNERYDIYVRLDERFRQDRETIADLRLQAPSGAWVRLGDVASVNIASG 837
Query: 810 PPMLKSENGRLISWVFVDIQGTSIGEYIQTAKSALEAELNLPPRYSYSFAGQYEYMQRVD 869
PP ++ ++ + V ++QG +G + ++A+ +++LP YS GQ+E QR
Sbjct: 838 PPQVRRDDVQRRVVVQANVQGRDMGSVVADIRAAIAEQVDLPTGYSVDIGGQFENQQRAQ 897
Query: 870 AKLKQVVPLAIGIIFILLMLTFGSGKQASMIMLSLPFALVGSTWLLYLLDYNLSVAVAVG 929
+L VVPL++ +I +LL F S QA +I++++P A++G + L+L LSV +VG
Sbjct: 898 KRLSLVVPLSLALIALLLYFAFASVGQAMLILVNVPLAVIGGVFSLWLSGQYLSVPSSVG 957
Query: 930 MIALAGVAAEFGVVMLVYLNNAIKDRDALGHYHNESDLKAALVEGAVMRIRPKAMTVATI 989
I L GVA GVVM+ +N IKD + A +GAV R+RP MT T
Sbjct: 958 FITLFGVAVLNGVVMVESINQRIKD---------GLPVSEAAFDGAVSRLRPVLMTAVTS 1008
Query: 990 FFGLLPIMWGAGSGNEVMQKIAAPMVGGMVTAPLLSLFVLPALY 1033
GL+P++ G G E+ + +A+ +VGG++TA L+LFVLP L+
Sbjct: 1009 ALGLIPMLLSNGVGAEIQKPLASVIVGGLITATFLTLFVLPVLF 1052
Score = 52.8 bits (125), Expect = 1e-10
Identities = 74/359 (20%), Positives = 151/359 (42%), Gaps = 47/359 (13%)
Query: 168 LQSVEGVSEVATVGGMEQTY---QIVLEPDKLAI--YKLDIATIKAAITRANSEAGGSVV 222
++ ++G +VA MEQ Q+V++P++ A+ Y LD+A + + A +
Sbjct: 732 VKKIDGTRDVA----MEQIVGEAQLVVKPNRRALSRYGLDVADVMEVVRNGLGGASAGQI 787
Query: 223 EMAEAEYMVRAK---GYRQTLDDFREIPLGITTGAGTPLLLKDVATI---------RKGP 270
Y + + +RQ + ++ L +GA + L DVA++ R+
Sbjct: 788 INGNERYDIYVRLDERFRQDRETIADLRLQAPSGAW--VRLGDVASVNIASGPPQVRRDD 845
Query: 271 ASRRGIAELDGEGEVVGGIIVMRYGENALATIDAVKAKLDELKAGLPDGVEIVPTYDRSQ 330
RR + + + +G +G ++ A I A A+ +L G V+I ++ Q
Sbjct: 846 VQRRVVVQANVQGRDMGSVV---------ADIRAAIAEQVDLPTGY--SVDIGGQFENQQ 894
Query: 331 LIQNSVDNLLTKVVEEMLVVGLVCLLFLLHARSTLVAVFTLPLSILIAFIVMNHMGINAN 390
Q + L + L+ L+ F ++ L+ V +PL+++ + G +
Sbjct: 895 RAQKRLS--LVVPLSLALIALLLYFAFASVGQAMLILV-NVPLAVIGGVFSLWLSGQYLS 951
Query: 391 IMSLGGIAIAIGAVVDGAIVMIENLHKHLEHFKRQHEREPSTREHWEVVTQASLEVGPAL 450
+ S G G V +VM+E++++ ++ + P + ++ A + P L
Sbjct: 952 VPSSVGFITLFGVAVLNGVVMVESINQRIK------DGLPVSEAAFD---GAVSRLRPVL 1002
Query: 451 FFSLLIITLSFIPVFALEAQEGRLFAPLAYTKTFAMAAASVLAITLVPVLMGYFIRGKI 509
+ + L IP+ + PLA + A+ L + ++PVL +F +GK+
Sbjct: 1003 M-TAVTSALGLIPMLLSNGVGAEIQKPLASVIVGGLITATFLTLFVLPVLFAWFSKGKL 1060
Score = 47.0 bits (110), Expect = 7e-09
Identities = 64/300 (21%), Positives = 122/300 (40%), Gaps = 44/300 (14%)
Query: 777 RDSLEKLRALPVITKSGHYLPLGNLADIQI---------------SDGPPMLKSEN-GRL 820
+ LE++R +P+ T G + + ++A + + SDG K E G +
Sbjct: 243 KQGLEQIRQVPLKTVDGTTITVSDVAKVNLGSEIRQGAVTMTRRTSDG----KVETLGEV 298
Query: 821 ISWVFVDIQGTSIGEYIQTAKSALEAELNLPPRYSYSFAGQYEYMQRVDAKLKQVVP--- 877
+S + + G + I + +E +N F Y+ V + VV
Sbjct: 299 VSGIVLKRLGANTKSTIDGVNARIE-RINQALPEGVKFEAYYDQADLVTQAVDTVVNALL 357
Query: 878 LAIGIIFILLMLTFGSGKQASMIMLSLPF----ALVGSTWLLYLLDYNL----SVAVAVG 929
LA I ++L L + + ++++S+P AL+ W + L NL +AVA+G
Sbjct: 358 LAFVFIVVILALFLMNLRATLLVLISIPISIGIALMVMAW--FGLSANLMSLGGIAVAIG 415
Query: 930 MIALAGVAAEFGVVMLVYLNNAIKDRDA----------LGHYHNESDLKAALVEGAVMRI 979
M+ V + + +A D+D + H+ + L E
Sbjct: 416 MLVDGSVVMVENMFKHLTHPDATHDKDRQTMVQDDPDPVDAAHDSHGIALRLQEAGREVA 475
Query: 980 RPKAMTVATIFFGLLPIMWGAGSGNEVMQKIAAPMVGGMVTAPLLSLFVLPALYLLVYRK 1039
RP A I +P+ G ++ Q +A ++ M++A +++L ++PAL ++RK
Sbjct: 476 RPIFFATAIILVVFMPLFSFEGVEAKLFQPMAISIMLSMLSALVVALIIVPALATYLFRK 535