Pairwise Alignments

Query, 872 a.a., DNA topoisomerase I (RefSeq) from Shewanella amazonensis SB2B

Subject, 869 a.a., DNA topoisomerase I from Pseudomonas putida KT2440

 Score = 1188 bits (3073), Expect = 0.0
 Identities = 580/873 (66%), Positives = 711/873 (81%), Gaps = 6/873 (0%)

Query: 1   MGKSLVIVESPAKAKTINKYLGKEFIVKSSVGHIRDLPTSSAAEGKASTKSAAEVRKMNP 60
           MGKSLVIVESPAKAKTINKYLG +++VKSS+GHIRDLPTS +A   AS + AA+  K   
Sbjct: 1   MGKSLVIVESPAKAKTINKYLGNQYVVKSSIGHIRDLPTSGSAS--ASKEPAAKRGKAAG 58

Query: 61  EEKAKYKAQKDKQALVARMGVDPEHGWQANYQVLPGKEKVVKELQSLASSADQIYLATDL 120
           E  A    +K ++ LVARMGVDP+HGW+A Y++LPGKEKV++EL+ LA  AD IYLATDL
Sbjct: 59  EAPALSPKEKARRQLVARMGVDPDHGWKAKYEILPGKEKVIEELRRLAKDADTIYLATDL 118

Query: 121 DREGEAIAWHLQEVIGGDESRYKRVVFNEITKGAIQEAFSRPTDLNTNMVNAQQARRFLD 180
           DREGEAIAWHL+E IGGD++RYKRVVFNEITK AIQEAFS+P +L+ + VNAQQARRFLD
Sbjct: 119 DREGEAIAWHLREAIGGDDTRYKRVVFNEITKKAIQEAFSQPGELDIDRVNAQQARRFLD 178

Query: 181 RVVGFMVSPLLWKKVARGLSAGRVQSVAVRLVVEREAEIKAFVPEEFWDVHATLSTPAAA 240
           RVVG+MVSPLLW K+ARGLSAGRVQSVAV+LVVERE EI+AF+PEE+W++HA L T   A
Sbjct: 179 RVVGYMVSPLLWAKIARGLSAGRVQSVAVKLVVEREREIRAFIPEEYWEIHADLGTAKNA 238

Query: 241 ELVMEVSRYRNEAFEPVTQSEAMAAVNALEKAAFTVTDREDKATSSKPSAPFITSTLQQA 300
           ++  EV+R + EAF+P+ +++AMAA+  L+ ++++V  RED+ TSSKPSAPFITSTLQQA
Sbjct: 239 KVRFEVAREKGEAFKPLNEAQAMAALEKLKASSYSVVKREDRPTSSKPSAPFITSTLQQA 298

Query: 301 ASTRLGFGVKKTMMLAQRLYEAGHITYMRTDSTNLSQEALENVRAHIEKEFGSKYLPESP 360
           AS RLGFGVKKTMM+AQRLYEAG+ITYMRTDSTNLS +AL+  R++IE+EFG +YLPE+P
Sbjct: 299 ASNRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSADALDMARSYIEREFGKQYLPEAP 358

Query: 361 IRYGSKEGAQEAHEAIRPSNVKVESATLIDMERDAQRLYELIWRQFVACQMTPAVYDATR 420
           + YGSKEGAQEAHEAIRPS+V      L  MERDA+RLYELIWRQF+ACQM PA Y +T 
Sbjct: 359 LVYGSKEGAQEAHEAIRPSDVNTHPTKLSGMERDAERLYELIWRQFLACQMPPAQYLSTS 418

Query: 421 ITAKAGDYELKASGRILKFDGWTRVQPALKKKNEEDNTLPDVQVGDMLSLKALDPKQHFT 480
           +T  AGD+EL+A GRILKFDG+TRV P   K  E+D  LP++  G+ L L  +DP QHFT
Sbjct: 419 VTVAAGDFELRAKGRILKFDGYTRVLPQQSKPGEDD-VLPEMVQGEALKLIQIDPSQHFT 477

Query: 481 KPPARYSEASLVKELEKRGIGRPSTYAAIISTIQDRGYVKVENRRFYAEKMGEIVTERLV 540
           KPPAR++EASLVKE+EKRGIGRPSTYAAIISTIQDRGYV + NRRFY+EKMG+IVTERL 
Sbjct: 478 KPPARFTEASLVKEMEKRGIGRPSTYAAIISTIQDRGYVTLHNRRFYSEKMGDIVTERLS 537

Query: 541 ESFSELMNYDFTAGMEQTLDDVAKGDKDWKGVLDGFYSGFTAKLEKAEAEPDAGGMRPNQ 600
           ESFS LM+Y FTA ME+ LDDVA+G++DWK VLD FY  F+ KL+ AE+  D  GMR NQ
Sbjct: 538 ESFSNLMDYGFTADMEENLDDVAQGERDWKNVLDEFYGDFSKKLQTAESSED--GMRANQ 595

Query: 601 MVLTDIPCPTCGRQMGIRTGTTGVFLGCSGYALPPKERCKTTLNLTPGEEAISDSSEDAE 660
             +T+IPC  CGR M IRT +TGVFLGCSGY+LPPKERCK T+NL PG+E  +D   ++E
Sbjct: 596 PTMTNIPCKECGRPMMIRTASTGVFLGCSGYSLPPKERCKATVNLVPGDEIAADDEGESE 655

Query: 661 TDALRAMHRCGKCGMAMDSYLLDETRKLHVCGNNPECDGYEVEKGAFKLKGYEGPIIECD 720
           +  L   HRC  C  AMD+YLLDE  KLH+CGNNP+C GYE+E+G +++KGYEGP +ECD
Sbjct: 656 SRVLLGKHRCPICATAMDAYLLDEKHKLHICGNNPDCVGYEIEEGNYRIKGYEGPSLECD 715

Query: 721 RCGSDMELKNGRFGKYFGCTNESCKNTRKLLKNGEAAPPKEDPIHLPELKCTKSDAYFVL 780
           +CGS+M+LK GRFGK+FGCTN +CKNTRKLLK+GEAAPPK D + +PELKC K D  +VL
Sbjct: 716 KCGSEMQLKTGRFGKFFGCTNPACKNTRKLLKSGEAAPPKMDKVDMPELKCEKVDDTYVL 775

Query: 781 RDGAAGIFLAASTFPRSRETRAPLVEELKKYREALWPKYQYLADAPVEDAEGNKALVKFS 840
           RDGA+G+FLAAS FP++RETRAPLV E+  ++  + PKY +L DAP +D +G  A++++S
Sbjct: 776 RDGASGLFLAASQFPKNRETRAPLVLEIVPHKHEIDPKYHFLCDAPQKDPDGRPAVIRYS 835

Query: 841 RKTKEQYVATEVNGKATGWSAHFKDGKW-VESK 872
           RKTKEQYV +EV+GK TGW A +    W VE K
Sbjct: 836 RKTKEQYVQSEVDGKPTGWKAFYDGNAWKVEDK 868