Pairwise Alignments

Query, 817 a.a., penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase from Pseudomonas putida KT2440

Subject, 835 a.a., penicillin-binding protein 1A from Vibrio cholerae E7946 ATCC 55056

 Score =  625 bits (1613), Expect = 0.0
 Identities = 346/815 (42%), Positives = 482/815 (59%), Gaps = 60/815 (7%)

Query: 14  AVICALVLGVS---GAFLYLSPSLPSVESLRSIQLQIPLRVYSSDGKLIAEFGEMRRSPI 70
           ++IC ++LGV+   G + Y+   LP V +LR +QLQ P++V+S DGKLIA+FGE RR P+
Sbjct: 21  SLIC-IILGVTTIFGFYFYVKSDLPDVATLRDVQLQTPMQVFSQDGKLIAQFGEKRRIPL 79

Query: 71  RFAEIPPQFIQALLSAEDDNFLNHYGVDPSSLMRAATQLVKTGHIQTGGSTITMQVAKNF 130
           +  E+P + I+A+++ ED  +  HYG DP  + RAA  ++ +G    G STIT Q+A+NF
Sbjct: 80  KLEEMPKELIEAVIATEDSRYYEHYGFDPIGITRAAFAVLASGSASQGASTITQQLARNF 139

Query: 131 FLTSERSFSRKTNEILLALQIERELTKDEILELYVNKIYLGNRAYGIDAAAQVYYGKSIR 190
           FL++E+   RK  EI +A+ IE+ L+K EILELY+NKIYLG R+YG+ AAAQ Y+GK ++
Sbjct: 140 FLSNEKKVMRKVKEIFIAIHIEQLLSKQEILELYLNKIYLGYRSYGVGAAAQAYFGKEVK 199

Query: 191 DVSLAQMAMIAGLPKAPSRFNPLANPVRAKERRDWILGRMYKLGKIDQASYEAALAEPLN 250
           D++L ++A+IAGLPKAPS  NP+ +  RA  RR+ +L RM     I +A Y+AA AEP+ 
Sbjct: 200 DLTLGEIALIAGLPKAPSTMNPIYSVERATNRRNVVLQRMLDEKYITKAEYDAARAEPVL 259

Query: 251 ASYHVPTPEVNAPYIAEMARAEMVGRYGSD-AYTEGFRVTTTVPSDMQEMANKAVLKGLS 309
             YH    E+NAPY+AE+ARA MV RYG + AYT G  V TTV S +Q  AN+A +  L 
Sbjct: 260 PKYHGAEIELNAPYVAEIARAWMVERYGEEAAYTSGMNVYTTVDSKLQRAANQAAINNLL 319

Query: 310 DYDERHGYRGPEARFPGRTQAAW-----LQELGKQRTLGGLEPAIVTQVEHTGLKVLTRD 364
            YDERHGYRG E       Q AW      + L  + T G + PA V  VE    +V  + 
Sbjct: 320 AYDERHGYRGAEKELWQVNQPAWSSTQLSEYLSNEPTYGDMFPAAVLSVEEKSAQVWVKS 379

Query: 365 GQEAQVAWDTMKWARPFINNNAQGRSPQSPADVAQVGDLVRLQ-RLDDGTL---KFSQVP 420
                +AW+ M WAR FIN++ QG  P+S  +    G  + ++ R  DG +   K +QVP
Sbjct: 380 YGVQTIAWEDMNWARRFINDDRQGPLPKSANEFLAAGQQIWVRPRTQDGAITAWKLTQVP 439

Query: 421 VAQSALVTLDPNNGAIRALVGGFSFEQSNYNRAVQAKRQPGSSFKPFIYSAALDSGYTAS 480
            A +A V ++P NGA+ ALVGGF+F  + +NRA Q+ RQ GSS KPFIYSAAL+ G T +
Sbjct: 440 NANTAFVAMNPENGAVTALVGGFNFVHNKFNRATQSVRQVGSSIKPFIYSAALNKGLTLA 499

Query: 481 SLVNDAPIVFVDESVDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQAMGVDRTID 540
           +L+NDAPI   DES    WRPKN   T+ GP R+R  L +S+N++++R+L+ +G+D T +
Sbjct: 500 TLINDAPINQWDESQGTAWRPKNSPPTYTGPTRLRIGLAQSKNVMAVRVLREVGLDETRE 559

Query: 541 YIAKFGFNKQDLPRNLSLALGTATLTPMEIATGWSTFANGGYKITPYLIERIESRSGETL 600
           Y+ +FGF    LPR+ ++ALG  +LTP+++A G+S FAN GY + P+ I R+E+  G   
Sbjct: 560 YLTRFGFKLDQLPRSETIALGAGSLTPVQMAQGFSVFANNGYFVEPFYISRVENPFGNIE 619

Query: 601 FTANPARVPQGAQDQAGLAAPEQPISTAAMPGEAPSAFSQVAAASQAPAVAEQIIDGRTT 660
           F+A P  V                        E  S   + A    A   A ++I  +  
Sbjct: 620 FSAEPKVV---------------------CHRECSSELDEFAEQDAASPYAPKVISEQNA 658

Query: 661 YILTSML-----------QDVIKRGTGRRALALGRTDLAGKTGTTNESKDAWFSGYNADY 709
           ++   ML            D    GTG RA AL R D+ GKTGTTN+SKDAW++GY    
Sbjct: 659 FLTREMLYSNIWGGGEWSSDTGWNGTGWRAQALKRRDIGGKTGTTNDSKDAWYNGYAPGI 718

Query: 710 VTTVWVGF-DQPETLGR-------------REYGGTAALPIWMNFMGAALKDKPAHAPAE 755
           V   WVGF D    LG+              E GG  ALP W+ FM  AL+D P    A 
Sbjct: 719 VGVAWVGFDDHSRNLGKTAPNRNIEDDVSGAESGGKTALPAWVEFMSLALQDVPVQQKAV 778

Query: 756 PEGILSLRVDPVSGRAASPSTPNAYFELFKAEDSP 790
           P  I  +R+D  +G   +    ++ FE F+A   P
Sbjct: 779 PNNIARVRIDRDTGLLTNKLDSSSMFEYFEAGTEP 813