Pairwise Alignments

Query, 1030 a.a., RND efflux transporter from Pseudomonas putida KT2440

Subject, 1084 a.a., acriflavin resistance protein (RefSeq) from Shewanella loihica PV-4

 Score =  268 bits (684), Expect = 2e-75
 Identities = 263/1075 (24%), Positives = 466/1075 (43%), Gaps = 105/1075 (9%)

Query: 17   SITLFLIVLIAFAGTLAFFKLGRAEDPPFTVKQMTIITAWPGATAQEMQDLVAEPLEKRM 76
            +IT  L +L    G  A     + E+P   V    I   +PGAT  E++ LV +P+E+ +
Sbjct: 31   AITPLLALLGLLLGLFAVMVTPKEEEPQIDVTFADIYIPFPGATPSEVEHLVTQPMEEVI 90

Query: 77   QELRWYDRTETYTRPGLAFTMVSLQDKTPPSA----VQEEFYQARKKAGDQA-----KLM 127
             +++  D   ++++P  A  +   +   P +     +  + Y  + K   QA     ++ 
Sbjct: 91   SQIKGIDTLYSFSQPDGALIIAIFEVGIPRNEAIVKLYNQVYSNKDKVASQAGVGEPQIK 150

Query: 128  PAGVIGPMLNDEFSDVTFAVYALKAKGEPQRQLVRDAETLRQQLLHVPGVKKVNIIGEQA 187
            P G+      D+   V+  +++ K K +   QL   A+ L  +L  +PG +++  +G   
Sbjct: 151  PRGI------DDVPIVSLTLWS-KDKAQSAEQLTHIAKGLESELKRIPGTREIYSVGSHE 203

Query: 188  ERIFVSFSHDRLATLGITPQDIFSALDNQNALSPSGSVETQGPQVVVRVDGAFDQLAKIR 247
              + V     +++  G+T  DI  +L + N +S   S+     ++ V+  G F +  +  
Sbjct: 204  ISLNVRIDPAKMSFYGLTYDDINRSLSSNNHVSMPVSLVQDNQEIKVQT-GQFLKSKQEV 262

Query: 248  ETPVVA-------QGRPLKLSDVADVERGYEDPATFLVRNDGE---PALLLGIVMREGWN 297
            E  VVA       Q  P+ L D+A +    + P       D     PA+ + I  + G N
Sbjct: 263  EQLVVAVYQDESGQSAPVYLGDIAKISLNSDIPTQHAWHGDKSAIYPAVTIAIGKQPGEN 322

Query: 298  GLDLGKALEAETAKI-NEGMPLGMTLSKVTDQAVNITSSVDEFMIKFFVALLVVMLVCFL 356
             +D+   +     KI N  +P  + ++   +         +  ++K   A   V+++ FL
Sbjct: 323  AVDIANVILERLDKIDNILVPDDVNITVSRNYGKTAGDKANTLILKLVFATSAVVILVFL 382

Query: 357  SMGWRVGVVVAAAVPLTLAIVFVVMAATGKNFDRITLGSLILALGLLVDDAIIAIEMMVV 416
            +MG R  VVV  A+ +TLAI      A G   +RI+L +LI ++G+LVDDAI+ +E +  
Sbjct: 383  TMGLRESVVVGIAIIITLAITLFASWAWGFTLNRISLFALIFSIGILVDDAIVVVENIHR 442

Query: 417  KMEEG-YDRIKASAYAWSHTAAPMLSGTLVTAIGFMPNGFAQSTAGEYTSNMFWIVGIAL 475
             M  G    ++    A      P +  T       MP  F     G Y S +     + +
Sbjct: 443  HMALGKRSFVELIPVAVDEVGGPTILATFTVIAALMPMAFVSGLMGPYMSPIPINASMGM 502

Query: 476  IASWVVAVAFTPYLGVKLLPRIKTIEGGHAAIYNTRHYNRFRALLGWVIAHK-------W 528
            + S  +A   TP+L  KLL   +   G      + R    F  L+   +  K        
Sbjct: 503  LISLAIAFIVTPWLATKLLKGHQHQGGDGEHDVDDRMLRLFTRLISPFVRGKQAGKARIG 562

Query: 529  LVAGTVVSTFVAAVLGMG-LVKKQFFPTSDRPEVLVELQMPYGTSIEQTNATAIKVESWL 587
            L A   +   +A  L +G LV  +  P  ++ E  V L MP GT +EQT      +   L
Sbjct: 563  LGAAIALLIMIAVSLPVGQLVVLKMLPFDNKSEFQVMLDMPEGTPVEQTQRVLKALAMEL 622

Query: 588  RQQEEAKIVTTYIGQGPP--------RFFLAMAPELPDPSFAKIVVLTENQGAREALKHR 639
             + EE      Y G   P         +FL  + EL D     I V   ++G R+   H 
Sbjct: 623  DKVEEVDNYQLYAGTAAPMNFNGLVRHYFLRQSQELGD-----IQVNLVDKGDRDRDSHS 677

Query: 640  LREAASEGLAPGAQ-----VRVTQLVFGPYSPYPVAYRVMGPDASQLRQIAARVQSVLQA 694
            +       L   A+     V+V ++  GP    P+   V GP+A      A  +Q +   
Sbjct: 678  IASEVRRALQATAKQYHANVKVVEVPPGPPVWSPILAEVYGPNAEMRETAANALQQLFHD 737

Query: 695  SPMMKTVNTDWGPLVPTLHFSLNQDRLQSVGLTSASVSQQLQFLLTGVPITSVREDIRSV 754
            +  +  ++         ++    Q + Q V +  A  S      L GVP +++  D+ + 
Sbjct: 738  TQDVVDID---------IYLPAAQQKWQ-VNIDRAKAS------LMGVPYSNI-VDLVAT 780

Query: 755  QVVGRAAGQI-------------------RLDPAQIENFTLVGSNGQRVPVSQIGDVSIR 795
             V G+A   +                   ++D  Q+ N  L  ++G  VPVS++  +  R
Sbjct: 781  SVGGKAVSYLHKPNQKSPVPIKLQLEEGAKVDLEQVLNLRLTNASGNSVPVSELITIHKR 840

Query: 796  MEDPILRRRDRTPTMTVRGDIAEGLQPP-----DVSTAIWKD-----LQPIVTQLPAG-- 843
              D  + R++  P + V  D+A  L  P     +++ +I ++      Q  V Q P+G  
Sbjct: 841  AIDAPIIRKNMIPMIMVVADMAGPLDSPLYGMFEIAGSINQEGGLGFDQHYVNQ-PSGLD 899

Query: 844  -YKIEMAGSIEESAKASQAIVPLLPIMIALTLLIIILQVRSISAMVMVFLTSPLGLIGVV 902
               +   G  + + +  + +     + +    L+++ Q RS S  +++    PL +IGV+
Sbjct: 900  SIAVLWDGEWKITYETFRDMGIAYGVGMIAIYLLVVGQFRSYSVPLIIMAPIPLTIIGVM 959

Query: 903  PVLLLFGQPFGINALVGLIALSGILMRNTLILIGQIDHNQLEGLAPFDAVVEATVQRARP 962
            P   L G  F   +++G+IAL+GI++RN+++L+  I+     G+    AV+ +   RA+P
Sbjct: 960  PGHALLGAQFTATSMIGMIALAGIIVRNSILLVDFINQETAAGVPFEQAVIHSGAVRAKP 1019

Query: 963  VLLTALAAILAFIPLTHSVFWGTLAYTLIGGTFVGTIMTLVFLPAMYSIWFKIRP 1017
            ++LT LAA++  + +     +  LA +LI G  V T++TLV +P +Y    + RP
Sbjct: 1020 IMLTGLAAMIGALFILDDPIFNGLAISLIFGILVSTLLTLVVIPVLYYAVMRHRP 1074