Pairwise Alignments

Query, 1042 a.a., Multidrug efflux RND transporter MexD from Pseudomonas putida KT2440

Subject, 1045 a.a., The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family from Pseudomonas stutzeri RCH2

 Score = 1002 bits (2590), Expect = 0.0
 Identities = 520/1045 (49%), Positives = 711/1045 (68%), Gaps = 5/1045 (0%)

Query: 1    MSRFFIHRPNFAWVVALFISLAGLLVIPSLPVAQYPNVAPPQISITASYPGASAKVMVES 60
            MSRFFI RP FAWV+AL I LAG L I  LPV QYP++A P + I+ SYPGASA+ + ++
Sbjct: 1    MSRFFIDRPIFAWVIALVIMLAGGLSILKLPVNQYPSIAAPAVGISVSYPGASAQTVQDT 60

Query: 61   VTSIIEQSLNGAKGLLYYESTNNSNGVAEVMVTFEPGTDPDMAQVDVQNRLKQAEARMPQ 120
            V  +IEQ LNG  GL Y  S +NS+G   + VTF+ GT+PD+AQV VQN+L+ A   +PQ
Sbjct: 61   VVQVIEQQLNGIDGLRYISSESNSDGSMTITVTFDQGTNPDIAQVQVQNKLQLATPLLPQ 120

Query: 121  AVLTQGLKVEQASSGFLLIYALTSTAGNRGDTTALADYAARNINNELLRVPGVGKLQFFA 180
             V  QG++V +A   FL++  L ST G+  D   LA+Y   N+ + + R  GVG  Q F 
Sbjct: 121  EVQQQGIRVTKAVRNFLIVIGLVSTDGSL-DQRDLANYIVANMQDPISRTKGVGDFQVFG 179

Query: 181  SEAAMRVWVDPQKLVGYGLSIDDINSAIRGQNVQVPAGSFGSTPGASEQELTATLAVQGT 240
            ++ AMR+W+DP KL  + ++  D+++AI+ QNVQ+ +G  G  P    Q+L AT+  +  
Sbjct: 180  AQYAMRIWLDPAKLNSFSMTPVDVSTAIQAQNVQISSGQLGGLPALPGQQLNATVIGKTR 239

Query: 241  LDTPEAFAGIVLRANPDGSSVRLGDVARMAIGSENYNLSARLNGHPAVAGAVQLAPGANA 300
            L TPE F  I+L+ N DGS VRLGDVAR+ +G E Y +SA  NG PA   A++LA GANA
Sbjct: 240  LQTPEQFRNILLKVNSDGSQVRLGDVARVELGGETYAVSAHFNGKPAAGLALKLATGANA 299

Query: 301  IQTATLVKERLAELSQFFPEGVEYSVPYDTSRFVDVAIEKVIHTLIEAMVLVFLVMFLFL 360
            + T   V++ + EL  FFP GVE   PYDT+  +  +I  V+HTL+EA VLVFLVM+LFL
Sbjct: 300  LDTVEGVRKTIEELKPFFPPGVEVVYPYDTTPVISASITGVMHTLLEAFVLVFLVMYLFL 359

Query: 361  QNVRYTLVPSIVVPVCLLGTLMIMKLLGFSVNMMTMFGMVLAIGILVDDAIVVVENVERL 420
            QN R TLVP++ VPV LLGT  ++ + GFS+N +TMF M+LAIG+LVDDAIVVVENVER+
Sbjct: 360  QNFRATLVPTLAVPVVLLGTFGVLAVFGFSINTLTMFAMILAIGLLVDDAIVVVENVERV 419

Query: 421  MAEEGLSPVEATIKAMGQVSGAIIGITLVLAAVFLPLAFMSGSVGVIYQQFSVSLAVSIL 480
            M EEGLSP+EAT K+MGQ+ GA+IGI +VL+AV LP+AF  GS GVIY+QFS+++  +++
Sbjct: 420  MREEGLSPLEATRKSMGQIQGALIGIGVVLSAVLLPMAFFGGSTGVIYRQFSITIVSAMV 479

Query: 481  FSGFLALTFTPALCATLLKPVPHG-HHEKAGFFGAFNRGFARVTERYSLLNSELVARAGR 539
             S  +AL FTPALCATLLKP+    HHEK GFFG FNR F R    Y      ++ R   
Sbjct: 480  LSVLMALIFTPALCATLLKPIDKDDHHEKRGFFGWFNRTFERSVNGYERGVKAVLKRKAP 539

Query: 540  WMLAYVGILVVLGYSYLRLPEAFVPAEDLGYSVVDVQLPPGASRVRTDHTAEALEKFLMS 599
            ++L YV I+ V+   + R+P AF+P ED G     V  P G++  RT  + +A+  +L+ 
Sbjct: 540  FLLLYVLIVGVMVVLFTRIPSAFLPEEDQGVLFAQVMTPSGSTAERTQQSIDAMRSYLLE 599

Query: 600  R--DAVANSFIVSGFSFSGQGDNAALAFPTFKDWSQR-DKAQSAEAETAAINAQFAANGD 656
               D V + F V+GFSF+G+G ++ +AF   K WS+R +K  S  A        FA+  D
Sbjct: 600  EEGDIVRSVFTVTGFSFAGRGQSSGIAFIGLKPWSERTNKEDSVFALAQRAQQHFASFRD 659

Query: 657  GAITAVMPPPIDGLGNSGGFALRLMDRGGLGREALLAARDQLLARANGNPVILYAMMEGL 716
              + A  PP +  LGN+ GF   L DR G+G++ L  ARD+ +  A+ +PV+       L
Sbjct: 660  AQVFAFAPPAVMELGNATGFNFFLQDRAGVGQQVLQQARDKFMQLASQSPVLTRVRPNTL 719

Query: 717  AEAPQLRLHIDREKARALGVSFEAINSTLATAFGSAVINDFTNAGRQQRVVVQAEQGERM 776
             + PQ ++ ID EKAR LG+S   INSTL+ A+G   +NDF + GR ++V +Q     RM
Sbjct: 720  RDEPQYQVLIDDEKARVLGISLAEINSTLSIAWGGRYVNDFIDRGRVKKVYLQGVADARM 779

Query: 777  TPESVLRLYAPNANGEQVPFSAFVTTQWEEGPVQLVRYNGYPSIRIAGDASPGHSTGQAM 836
             PE + + Y  N  GE VPFSAF + +W  G  +L RYNG  +I + G+ +PG+S+G AM
Sbjct: 780  NPEDLAKWYVRNDAGEMVPFSAFASGEWTYGSPKLSRYNGVSAIEMLGEPAPGYSSGDAM 839

Query: 837  AEMERLVSELPPGIGYAWTGLSYQEKVSSGQAASLFALAILVVFLLLVALYESWAIPLTV 896
            AE+ER+V++LPPG+GY+WTG SY+E+++  Q  +L+AL++LVVFL L ALYESW+IP +V
Sbjct: 840  AEVERIVAQLPPGVGYSWTGQSYEERLAGSQTLALYALSLLVVFLCLAALYESWSIPFSV 899

Query: 897  MLIVPIGALGAVWAVTLTGMPNDVYFKVGLITIIGLAAKNAILIVEFAKELWEKGYSLCD 956
            ML+VP+G +GA+    L G+ N+V+F+VGL+T IGL+A+NAILIVEFAK L E+G S  D
Sbjct: 900  MLVVPLGIVGALAFTMLRGLSNEVFFQVGLVTTIGLSARNAILIVEFAKALHEQGMSYAD 959

Query: 957  AAIEAARLRFRPIVMTSMAFILGVVPLAIASGAGAASQRAIGTGVIGGMLSATLLGVVFV 1016
            AA++A R+R RPI+MTS+AFILGVVPLA+ASGAGA S+ AIGTGVIGGML+A +L + ++
Sbjct: 960  AALQACRMRLRPIIMTSLAFILGVVPLAVASGAGAGSKHAIGTGVIGGMLTAAVLAIFWI 1019

Query: 1017 PVCFVWVLTLLKRKPSPVQQAVEEA 1041
            P+ +V + T   R     Q A EE+
Sbjct: 1020 PLFYVMICTFFDRTKPANQAAKEES 1044