Pairwise Alignments

Query, 436 a.a., folypolyglutamate synthase/dihydrofolate synthase from Pseudomonas putida KT2440

Subject, 421 a.a., bifunctional tetrahydrofolate synthase/dihydrofolate synthase from Vibrio cholerae E7946 ATCC 55056

 Score =  327 bits (837), Expect = 6e-94
 Identities = 183/420 (43%), Positives = 248/420 (59%), Gaps = 15/420 (3%)

Query: 7   LGEWLAYLEQLHPSAIDMGLERSQKVLARLALGKLAPRVVTVTGTNGKGSTCAFVASLLR 66
           L  WL YL  +H SAID+GLER Q V  +  L K AP V+TV GTNGKGSTCA + ++L 
Sbjct: 13  LAVWLDYLAHIHTSAIDLGLERVQAVAQKAKLTKPAPTVITVAGTNGKGSTCALMEAILL 72

Query: 67  AQGLKVGVYSSPHLLRYNERVVIDGQEASDERLCEAFAAVEAARGDISLTYFEMGTLAAF 126
             G  VGVYSSPHL+RYNERV I+GQ+ +DE   +AFA +E  RGDISL+ FE GTLAA 
Sbjct: 73  QAGYSVGVYSSPHLIRYNERVRINGQDLADEMHTQAFAHIEQERGDISLSLFEFGTLAAL 132

Query: 127 WLFYQSQLDAVVLEVGLGGRLDTVNVVDADFALVTSIGVDHVDYLGDTRELVAFEKAGIF 186
           +LF Q ++D ++LEVGLGGRLD  NVVD D +++TS+ +DH D+LG+   ++ +EKAGIF
Sbjct: 133 YLFEQQKVDVLLLEVGLGGRLDATNVVDHDVSVITSLALDHTDWLGNDIAVIGYEKAGIF 192

Query: 187 RPGKPALCGDLDPPGPLLDKAAELAAPLFLRGREFDLASAEG-CWSWRGTAADGAQVELR 245
           R GKPA+CG   PP  +   A ++ A L     +F         W+WR       + EL 
Sbjct: 193 RSGKPAICGQPKPPATVAAHADDIGAKLHQVEIQFSYEKTSATTWNWR-----SGRFELT 247

Query: 246 DLPLLDLPMENATLALQAFLLMGLPWNAAQVRQALLDTRITGRLDLRNVNWQGKPVALLL 305
           DLP+  LP+ NA  AL A    GL  +   +   L + ++ GR+ + +         ++L
Sbjct: 248 DLPIPSLPLPNAATALMALGCSGLAISDINIVDGLRNAQLAGRMQVIS-----HQPTIVL 302

Query: 306 DVGHNPHAAQYLARRLAARPLKGRRLAVFGLLADKDLEGVIAPLQGLIDDWAVAPLDTPR 365
           DV HNPH+A YL ++L  R  +     VFG+L DKD+   +  L   +  W  A L  PR
Sbjct: 303 DVAHNPHSAHYLVQQLTQRYPERTIHLVFGMLHDKDIASTVVELSPAVTHWYPASLSGPR 362

Query: 366 SRPAAELASSLANLGATVKSYVSVDAALEGQCAQATADDQILLFGSFFCVAQALE-WLER 424
           +  AA+L   L    A +  Y +  +A E    QA A D I++ GSF  V + LE W +R
Sbjct: 363 AATAAQLCQYLP---ADITQYANPVSAFEAALTQAGAQDVIVVAGSFHTVGEVLEHWQKR 419