Pairwise Alignments
Query, 1540 a.a., Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) from Hydrogenophaga sp. GW460-11-11-14-LB1
Subject, 1538 a.a., Phenolpthiocerol synthesis type-I polyketide synthase PpsB from Mycobacterium tuberculosis H37Rv
Score = 521 bits (1342), Expect = e-151
Identities = 476/1559 (30%), Positives = 699/1559 (44%), Gaps = 161/1559 (10%)
Query: 9 AHAMAIVGMAGRFPGASD-LDAFWRNIREGVEALEPFSEADLQEAGV----DPALSGQPQ 63
A +A+VG+ RFPG D ++FW + G A+ AD +A DP G+
Sbjct: 33 AEPVAVVGIGCRFPGDVDGPESFWDFLVAGRNAISTVP-ADRWDAEAFYHPDPLTPGR-M 90
Query: 64 YVRKGTVLENADHFDAGFFGMSPREAQVIDPQQRIFLECAWEALEHAGYAPGAIAQA-VG 122
+ G + + FDA FFG++PREA +DPQQR+ LE AWEALEHAG P ++
Sbjct: 91 TTKWGGFVPDVAGFDAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGIPPDSLGGTRTA 150
Query: 123 VYAGASMNTYLLSQILRDPALAASVGGYQLMLGNDKDFLCTRVSYKLDLHGPSMTLQTAC 182
V G N Y S + P + G GN R+SY L L GP++ + TAC
Sbjct: 151 VMMGVYFNEYQ-SMLAASPQNVDAYSG----TGNAHSITVGRISYLLGLRGPAVAVDTAC 205
Query: 183 STSLVAVQVACRALERHECDIALAGGVSVNFPQRGGYLFQEGMILSPDGHCRPFDADAKG 242
S+SLVAV +AC++L E D+ALAGGVS+ +LSP G C FDA A G
Sbjct: 206 SSSLVAVHLACQSLRLRETDLALAGGVSITLRPETQIAISAWGLLSPQGRCAAFDAAADG 265
Query: 243 TRPGAGAGIVVLKRLADALADGDTIHAVIRGAAINNDGAGKAGYTAPSVDGQVEAIATAQ 302
G GAG+VVLKRL DA+ DGD + AV+RG+A+N DG G TAP+ Q + IA A
Sbjct: 266 FVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVNQDGRSN-GVTAPNTAAQCDVIADAL 324
Query: 303 MLADVDPRSIGYLEAHGTATPLGDPIEIAALRQVFEAGTADQGFCRLGSLKANLGHLDAA 362
DV P S+ Y+EAHGT T LGDPIE AL + G C LG++K N+GHL+AA
Sbjct: 325 RSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAATYGHG---GDACALGAVKTNIGHLEAA 381
Query: 363 AGVAGLIKTVLALQHRELPPLVNFRQANPQLNLDRSPFTASAQAAPWPAQAGPRRAGVSS 422
AG+AG IK LA+Q +PP ++F Q NP ++ + F Q +PWP GPRRA VSS
Sbjct: 382 AGIAGFIKATLAVQRATIPPNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEGPRRAAVSS 441
Query: 423 FGIGGTNAHVVLEEAPAIERVENAGQP---QLLVLSARSEAALEAATQRLRDHLTG-HAD 478
FG+GGTNAHV++E+ + V G+ LV++ ++ + A Q L D + G A+
Sbjct: 442 FGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTLVVTGKTAQRMAATAQVLADWMEGPGAE 501
Query: 479 LDLRDVAWTLQEGRRAFPHRRTLVAASTADAVA---ALGAPKRAPVHTARHEGGERP-VA 534
+ + DVA T+ R T+VA A A+A AL A + AP + +G P
Sbjct: 502 VAVADVAHTVNHHRARQATFGTVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGTV 561
Query: 535 FLFSGQGSQFAGMGADLYEQHAVYRDAIDRCAELLREPMGRDLRELLFAPAGDLTINETR 594
F++SG+GSQ+AGMG L + A+ + E G LR+++ + I +
Sbjct: 562 FVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVGIEQ-- 619
Query: 595 YAQPALFVTEYALAMLWQSWGVRPAAMLGHSIGEYVAAHLAGVMSLADALALVAARGQLM 654
Q L + L LW+S+GV+P ++GHS+GE AA +AG ++ A+ L + A R +LM
Sbjct: 620 -IQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRARLM 678
Query: 655 QSMA-PGGMAAVQLSASELQKWLAT-PAGTLEIAAVNAPNLCAISGPHEALAACLQQLKE 712
++ GGMA + L A+ + +A P T+ I N+P I+GP E + + +++
Sbjct: 679 APLSGQGGMALLGLDAAATEALIADYPQVTVGI--YNSPRQTVIAGPTEQIDELIARVRA 736
Query: 713 QGIDAQPLHTSHAFHSSMMEGVLAPFTALVEKVALAAPGVPYVSNVTGLWITPAQATSPA 772
Q A ++ A H+ M+ L P A+ ++A P P + ++ + T P
Sbjct: 737 QNRFASRVNIEVAPHNPAMD-ALQP--AMRSELADLTPRTPTIGIISTTYAD--LHTQPI 791
Query: 773 YYAEH----LRRAVLFEAGVRTL--AADPSLHLLEVGPGRSLATLAGMALGVEGVRRTS- 825
+ AEH +R V F+ + + AD + H L T A +A +E R +
Sbjct: 792 FDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQA-IADTLEDAHRPTK 850
Query: 826 -----LSMGH-ARDARSASQAMLEAASRLWLAGVSLDWAGLHGPVRPRRVPLPTYPFERK 879
LS+G RDA + + L+ A ++ H P +PT P++
Sbjct: 851 SAAKYLSIGTLQRDADDT----VTFRTNLYTADIAHPPHTCHPP--EPHPTIPTTPWQHT 904
Query: 880 RHAVDPVAPKAAPP------KAVVPVAEAAVQRPVDDWFWEPSWQRAGALPTGLAPVTEA 933
H + P A P K VV + R ++DW + +W A+ P T A
Sbjct: 905 HHWIATTHPSTAAPEDPGSNKVVVNGQSTSESRALEDWCHQLAWPIRPAVSAD-PPSTAA 963
Query: 934 PGRWLVFRRDDAASQALVAALAAQGIEVVSVTAGSGFRPVSATHYEVAPDSQADHDQLFS 993
WLV A L LA A DS+ D +
Sbjct: 964 ---WLV-----VADNELCHELAR------------------------AADSRVDSLSPPA 991
Query: 994 ALGAAPLACVLHAWNTGDDAPQTLDAALPPGR-------RQAFDALICLARAL--GGVKR 1044
+ A +L A D+ L A PG Q F A LA A+
Sbjct: 992 LAAGSDPAALLDALRGVDN---VLYAPPVPGELLDIESAYQVFHATRRLAAAMVASSATA 1048
Query: 1045 AQPLPVLVLSSDREPVLGTEAVRPERALLLGPALLLPLDVPGVHCRAIDLAGSEWRPDAA 1104
P + +++ + +P+ + P A+L G L L+ P + IDL D+
Sbjct: 1049 ISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDL------DDSM 1102
Query: 1105 PRLAASLRAEVARPEPDG--VVAYRGRHRWTPTLMPRRLGADAGPLPLREGGTYLVTGGA 1162
P A A DG V YR R P L R L P+ L + LV G
Sbjct: 1103 PAELAVRHVLTAAHGTDGEDQVVYRSGARHVPRLQRRTL--PGKPVTLNADASQLVIGAT 1160
Query: 1163 GGIGLTLGQWLARHVRAARLVLVSRSAWPDRAQWDALLAAKDTPAPQKARITALREMEAA 1222
G IG L + LAR + A +V ++R D L + A
Sbjct: 1161 GNIGPHLIRQLAR-MGAKTIVAMARKP----GALDELTQC----------------LAAT 1199
Query: 1223 GAEVLLCSGDVADEAQMQAVVAMARARFGAVHGVVHAAGALGTGTVFEKTAQGIEAVLRP 1282
G +++ + D D A MQ + + G+ AA A + E T + + RP
Sbjct: 1200 GTDLIAVAADATDPAAMQTLFDRFGTELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRP 1259
Query: 1283 KLEGTLVLDRVLAGNGLDFFMMCSSISTAFGSAGMADYSAANAFQDAFAKSGLARS-SAR 1341
KL+ +L R + + F++ SS+S GS +A Y+A +AF D+FA G R+
Sbjct: 1260 KLDALALLHRRSLKSPVRHFVLFSSVSGLLGSRWLAHYTATSAFLDSFA--GARRTMGLP 1317
Query: 1342 VLAVGWDSWRDVGFSAAQGADPSHAALRYAIRPEEGADAFGRALASGLPHVYVTRQVMPD 1401
V W W+ + A D + + ++P A G P V V
Sbjct: 1318 ATVVDWGLWKSL---ADVQKDATQISAESGLQPMADEVAIGALPLVMNPDAAVATVV--- 1371
Query: 1402 MLRDVEALKAWLRQSGA---AAQSKPAAAEPGVAAPVDVQALAPNEIEAR-------IGA 1451
+ D L A R GA PA + G +L E R +GA
Sbjct: 1372 VAADWPLLAAAYRTRGALRIVDDLLPAPEDVGKGESEFRTSLRSCPAEKRRDMLFDHVGA 1431
Query: 1452 IWSELLGV---DDIGLDDDFFALGGHSLMATRIIARIEEQFGARLSLRDLFEGPSIRQL 1507
+ + ++G+ + + FF LG SLM+ + + E G L +F+ P++ L
Sbjct: 1432 LAATVMGMPPTEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSL 1490