Pairwise Alignments

Query, 479 a.a., 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Hydrogenophaga sp. GW460-11-11-14-LB1

Subject, 488 a.a., NAD-dependent succinate-semialdehyde dehydrogenase from Vibrio cholerae E7946 ATCC 55056

 Score =  331 bits (848), Expect = 4e-95
 Identities = 186/462 (40%), Positives = 265/462 (57%), Gaps = 4/462 (0%)

Query: 9   FIQGQWRDAQAGETLAVFNPATGKEIGRVAHARQADLDLALAAAQKGFETWRDTPAIERA 68
           FI GQW   +      V NP  G  IG V     A +  A+A AQ     W   PA  +A
Sbjct: 19  FINGQWILGEPQARQTVTNPFDGSLIGSVPLLSAAQVQEAIAGAQAAQILWCQQPAENKA 78

Query: 69  KVMRAAAGLMRERAGAIARLLTQEQGKPLAEAKGEAMAAADILEWFADEGLRVYGRIVPS 128
           K++R    L+ +   ++A+LLT EQGKPLAEA+GE   AA  +EW+A+E  R YG ++PS
Sbjct: 79  KILRRWYELIEQHHESLAKLLTIEQGKPLAEARGEIHYAASFVEWYAEEAKRAYGELIPS 138

Query: 129 RGNLAMRQMVLKDPVGPVAAFTPWNFPINQVVRKLAAALATGCSMIVKAPEETPAAPAEL 188
               A R MV + PVG VAA TPWNFP   + RK A A A GC++++K   +TP     L
Sbjct: 139 HKPDA-RIMVSRQPVGVVAAITPWNFPAAMITRKCAPAFAAGCAVVLKPAPDTPFTALAL 197

Query: 189 VRAFADAGLPAGVLGLVYGTPSEISSYLIAHPVIRKITFTGSTPVGKQLAAMAGQHMKRV 248
                 AG+P G+L +V G   EI   L     +RK++FTGST VGK L A +  ++K++
Sbjct: 198 ADLAQQAGIPDGLLQVVTGDAIEIGRVLTESKTVRKLSFTGSTGVGKLLMAQSANNVKKL 257

Query: 249 TMELGGHAPVIVAEDADVALAVKTAGGAKFRNAGQVCISPTRFLVHESIAKEFSAALVKH 308
           ++ELGG+AP IV EDAD+  A+     AKFRNAGQ C+   R  VH+++  +F+A LV  
Sbjct: 258 SLELGGNAPFIVFEDADINAAIDGVMVAKFRNAGQTCVCANRIYVHDAVYDQFAAKLVDR 317

Query: 309 AAGLAVGDGTTEGTQMGPLANPRRVTAMAEFTKDAVERGATLATGGERIGDEGN-FWRPT 367
            + L VG G   G  +GPL N   V  +     DA  +GA +  G   + + G+  ++P 
Sbjct: 318 VSRLNVGYGLDAGVNIGPLINDAAVAKVTSHIVDAQSKGAKVMFGA--LPEAGSRLFQPH 375

Query: 368 ILTDVPLDARVFNDEPFGPMAAVRSFNTLDEAIAEANRLPYGLAGYAFTRSLKNADLLAR 427
           +LT+V  + RV ++E FGP+AA+  F++  E I  AN    GLA Y +T+SL+ A  ++ 
Sbjct: 376 VLTEVTDEMRVADEETFGPLAALFRFSSEQEVIERANATDSGLAAYCYTQSLRRAWHMSE 435

Query: 428 RVDVGMLWVNMPAMPSAEMPFGGIKDSGYGSEGGPEAMEAYL 469
            ++ G++ +N   + +   PFGGIK+SG G EG    +E YL
Sbjct: 436 ALEAGIVGINEGLISTTLAPFGGIKESGLGREGAKHGLEEYL 477