Pairwise Alignments

Query, 276 a.a., 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) from Hydrogenophaga sp. GW460-11-11-14-LB1

Subject, 314 a.a., methylenetetrahydrofolate reductase from Caulobacter crescentus NA1000

 Score =  183 bits (465), Expect = 4e-51
 Identities = 100/280 (35%), Positives = 152/280 (54%), Gaps = 11/280 (3%)

Query: 5   ISLEFFPTKTPEGAVKLRAVRQQLYALKPEFCSVTFGAGGSTQDGTLQAVTEIMGE-GCP 63
           +S EFFP KTP+    L     +L  L P F SVT+GAGGST++ T + V  I+ E    
Sbjct: 25  VSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTYGAGGSTRERTHRTVKRILDETSLK 84

Query: 64  AAPHLSCIGQSSQSIRERLAAYTAAGIRRIVALRGDLPSGYGAGGE--------FRYASD 115
            A HL+C+G S + + E +  Y   G+R IV+LRGD P G G  G         +  A++
Sbjct: 85  PAAHLTCVGASREEVDEVIREYWETGVRHIVSLRGDPPPGEGGIGGVYVPRADGYANATE 144

Query: 116 LVAFIRQETGDRFHLEVAAYPETHPQAKSPQADLEAFAAKVKAGADSGITQYFFNADAYF 175
           L   +R      F + V  YPE HP++ S + D++    KV AGA  GI+Q+FF+ DA+ 
Sbjct: 145 LTKAVRAIAP--FEVLVGVYPEKHPESPSLEHDIDVLKQKVDAGATLGISQFFFDLDAFL 202

Query: 176 HFRDEMQRLGVDVPVVPGIMPITSSTQLMRFSDACGAEIPRWIRMRLQAFGDDTASIKSF 235
            F D+++  G+ +P+VPGIMP+T+   L + + AC   IP W+        +D  + +  
Sbjct: 203 RFVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTAIPSWLGNLFDGLENDAETRRLI 262

Query: 236 GLDVVTDLCERLRSGGVPGLHFYTMNQSAATTDIVQRLGL 275
              V  ++C +L+  G    HFYT+N++     I + LG+
Sbjct: 263 ACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVLGV 302