Pairwise Alignments

Query, 710 a.a., guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SpoT from Phaeobacter inhibens DSM 17395

Subject, 746 a.a., Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I from Variovorax sp. SCN45

 Score =  333 bits (854), Expect = 2e-95
 Identities = 225/718 (31%), Positives = 352/718 (49%), Gaps = 52/718 (7%)

Query: 23  IADAYAFGEQMHDGQFRHSGEPYFTHPVAVAAILTEQRLDDATIITALLHDTIEDTKASY 82
           +A A AF E +   +   +GE    H  AVAAI+ +    +A    + L    +      
Sbjct: 38  LARARAFAEPLIADETLDTGENTLAHADAVAAIVAKMGGSEAMQAASYLVYACQHLNRPQ 97

Query: 83  DEISTRFGDEVAMLVDGVTKLTNLQLSSRETKQA----------ENFRKLFMAMSKDLRV 132
           + I+  FGD  A L    TKL  +Q  +R   Q           EN RK+ +A S+DLRV
Sbjct: 98  EVIAKVFGDNFAALAVETTKLVRVQEQARSAAQGHHIEGAGAQTENVRKMLLAFSRDLRV 157

Query: 133 ILVKLADRLHNMRTIKAMRPDKQAQKARETMDIYAPLAGRMGMQWMREELEDLAFRVLNP 192
           ++++LA RL  +R   A +       ARE++ ++APLA R+G+  ++ E+EDL+FR L P
Sbjct: 158 VMLRLASRLQTLRHAAASKQPAPEGVARESLQVFAPLANRLGIWQVKWEIEDLSFRFLEP 217

Query: 193 EGRQSIIRRFVTLQRETGDVIHRITGDMRAELEKTGIEAEVFGRAKKPYSIWRKMQEKDQ 252
           E  + I R     + E    + ++   +  EL+  G++A V GR K  YSI +KM+ K  
Sbjct: 218 ETYKLIARLLDEKRIEREGHVEQLRSQLERELQNEGVKATVQGRPKNIYSIVKKMRGKSL 277

Query: 253 GFSRLSDIYGFRIITASEEDCYRALGAIHQRWRAVPGRFKDYISQPKSNGYRSIHAT--- 309
            F+++ DI   R++ +  +DCY AL  +H  ++ +   F DYI++PK NGY+S+H     
Sbjct: 278 DFAQVFDILALRVVVSDVKDCYAALAWVHSHFQPIDEEFDDYIARPKPNGYQSLHTVVRE 337

Query: 310 -VSGRDGKRVEVQIRTRQMHDVAETGVAAHWSYRD-------GVRSENPFAVDPAKWIAS 361
            V G+ GK +E+QIRT +MHD AE GVAAHW+Y++       GV +   +       IA 
Sbjct: 338 LVDGKPGKPIEIQIRTEEMHDHAEHGVAAHWAYKEAGHKGYAGVWASGEYDAK----IAV 393

Query: 362 LTEQFDAEEDHDEFLEAVKLEMYSDQVFCFTPKGDVIKLPKGATPIDYAYAIHTRIGHAC 421
           L +    E D    L+   L  + D+++  TP   +++LP+GATP+D+AY +HT +GH C
Sbjct: 394 LRQLLAWERDLSGGLQGQGL--FDDRIYVLTPDAAIVELPQGATPVDFAYTVHTTLGHRC 451

Query: 422 VGAKVDAIRVPLWTRLRNGQSVEIITAEGQTPQVSWLD----IATTGKARTAIRRALREA 477
            GA+VD   VPL T L NGQ+VEII A+   P   WL+       + +AR  +R      
Sbjct: 452 RGARVDGAMVPLNTPLSNGQTVEIIAAKEGGPSRDWLNAELGYLASHRARAKVRAWFNAQ 511

Query: 478 DRARFVKLGHELARSAFEHVGRKATDKALETAARALRVSTVDELLARLGAAVLTAHDVVQ 537
                V  G E      +  G+ A    LE  A  L   + D L   +G    +  ++  
Sbjct: 512 ITHETVARGREAVEKLLQREGKTAV--RLEDLASQLGFKSADHLFEVVGKDEFSLRNIET 569

Query: 538 AVY-PELAADDSDEVSPRRA------------VIGLEPGQSFERAPCCQPLPGERIIGIT 584
            +  PE A    D V  ++A            V+G+    + + A CC+P P + I G  
Sbjct: 570 LLRPPEPAPGPDDGVLIKKARGSEKSGKGGVLVVGVSSLMT-QLAKCCKPAPPDSIRGFV 628

Query: 585 YRGRGVVVHAADCDALGEVEDQP-ERWVDLHW---HSGTHPAVYGVTLELTIGNDAGVLG 640
            RG GV VH +DC     +  +  ER +D+ W     G    VY V + +   +  G+L 
Sbjct: 629 TRGHGVSVHRSDCSNFRTMASKDNERVIDVEWGAPKKGAEAPVYAVDVAVEAADRQGLLR 688

Query: 641 RICTLIGEKKANISDLEFVDRKPDFYRLMINVELRDVEQLHSLMLMLEAESDVAAVAR 698
            I  +   +K N+  ++    K   + +   VE+ D  +L  ++ ++ A   V +  R
Sbjct: 689 DISDVFAREKMNVIGVQTQSIKGTAW-MTFTVEIADAARLTQVLGVVTAVIGVRSARR 745